Posted by admin on Feb 29, 2024 in |
Nowadays, many clinical studies have provided reliable results on the effects of several herbal medicines on many diseases such as kidney problems. The objective of this study is to evaluate in-vitro the antiurolithiatic activity of polyphenols, flavonoids, and alkaloids fractions of the leaves of the species Ziziphus lotus. The quantification of the polyphenol and flavonoid fractions was carried out by spectrophotometric methods; on the other hand, the alkaloid fraction is quantified gravimetrically. The antiurolithiatic activity of the fractions is studied by the use of the turbidimetric and gravimetric techniques. The polyphenol content varies between 1198,696 ± 99,848 and 15270,751 ± 290,419 (μg GAE)/g). While flavonoids range from 97,340 ± 8,437 to 1745,864 ± 8,690 (μgQE/g). On the other hand, the alkaloid fraction represents 1. 26%. The polyphenols fraction showed a higher inhibition 89.80 ± 0.69 than the two other fractions which represent the values 84.17 ± 1.11 and 78.90 ± 1.40, respectively. The polyphenols fraction (AF: 86.66 ± 1.43) and flavonoids (DMF: 80.85 ± 2.03) show an increasing evolution...
Read More
Posted by admin on Feb 29, 2024 in |
Production of nanoparticles using plants is a new area of interest. Plum fruit extract was used for the biosynthesis of zinc oxide nanoparticles. Green synthesis of zinc oxide nanoparticles are considered as a eco-friendly methodusing materials from plants and other natural sources without using anyharmful chemicals. Plum fruit has many medicinal values such as antioxidant activity, cardiovascular activity, anti-inflammatory and antimicrobial effect. Present paper discuss about the green synthesis of zinc oxide nanoparticles using Prunus domestica (plum) fruit extract, Its characterization by analytical studies, antimicrobial and antioxidant studies. Plum fruit extract also subjected to phytochemical screening. The active constituents present in Plum were identified as alkaloids, glycosides, phenolics, flavonoids, proteins and carbohydrates. Nano particles were characterized by UV-Visible Spectroscopy, FT-IR and SEM studies. In the UV visible spectrometer absorption peak was observed at 362 nm, which is specific for zinc oxide nanoparticles. Synthesized zinc oxide nanoparticles were subjected to FT-IR analysis to detect the various characteristic functional group associated with the synthesized nanoparticles. The peaks indicate the characteristics functional group...
Read More
Posted by admin on Feb 29, 2024 in |
Introduction: Carcinoma cervix is the major health problem with increased morbidity and mortality. Around 60% of cases are diagnosed at an advanced stage, making the treatment more complex. Pap smear can able to detect precancerous and cancer of cervix along with infection and inflammatory pathologies making the clinician in timely and appropriate management. Objective: This study aims at detecting the prevalence of current trends of nonneoplastic and neoplastic lesions of cervix in patients who attending our tertiary care centre. Materials and Methods: This is a prospective study done in Srinivasan medical college and Hospital for a period of 6 months in patients who attended gynaecology department. Smears were made and stained with Pap stain after fixation in ethyl alcohol. Reporting was done based on the Bethesda system 2014. Results: Out of 500 cases, 495 cases (99%) were satisfactory for evaluation. Of these, 470 (94%) cases were negative for intraepithelial lesion/malignancy and 24 cases (4.8%) shown epithelial cell abnormalities. Nonspecific inflammation contributed 30.6% cases, infections like Bacterial vaginosis were seen...
Read More
Posted by admin on Feb 29, 2024 in |
Plants have been an important source of medicine with qualities for thousands of years. The therapeutic effects in the plants are due to the chemical compounds there in. Cynodon dactylon (L) Pers commonly known as Bermuda grass belongs to the family Poaceae. In ethnomedicinal practices, the plant Cynodon dactylon used in the treatment of various diseases and has pharmacological actions. Its health and nutritional benefits are well documented but very little about its bioactive compounds. The present study was carried to identify the phyto-constituents present in the methanolic extract of Cynodon dactylon (L.) Pers by GC-MS analysis to ascertain its usage by the local community as a plant possessing medicinal properties. In total 68compounds were identified. The major constituents were furfural (2.33%), 3-aminopyrazine 1-oxide levoglucosenone (1.39%) tetetrapentacontane (2.47%), 9-octadecanoic acid (2.27%), n- hexadecanoic acid (7.5%), Neophytadiene (1.30%) and benzene propanoic acid (1.91%). The above findings supported the traditional use of Cynodon dactylon in various...
Read More
Posted by admin on Feb 29, 2024 in |
Background: Neurological assessment of traumatic brain injury patients is of prime importance as it affects the therapeutic and prognostic decisions. GCS (Glasgow Coma Scale), a well recognised and often used scoring system in such cases has some drawbacks. We compared FOUR score (Full Outline of Unresponsiveness) with GCS with an objective to test its validity as an alternative to assess the severity of traumatic brain injury. Methods: This was a descriptive study, conducted on 70 patients admitted to the neurosurgical ICU of a tertiary hospital of a Medical college in Karnataka, India. In these patients, FOUR score and GCS were assessed at the time of presentation and serially thereafter up to a week. The predictive value and the correlation between full outline of unresponsiveness score and Glasgow Coma Scale was studied. Results: Most of the patients presenting with traumatic brain injury were males (84%) and belonged to younger age group of 18 to 30 years (48.6%). A statistically significant correlation was found between Full outline of unresponsiveness score and...
Read More
