Posted by admin on Jan 31, 2022 in |
Cubosomes are very stable nanoparticles, which consist of cavernous or honeycombed structures. Cubosomes are formed from some amphiphilic lipids and stabilized by a polymer. They are known as bicontinuous cubic phase liquid crystals. The bicontinuous word refers to the two continuous but non-intersecting aqueous regions by a lipid bilayer. Cubosomes are self-assembled liquid crystalline particles of a specific ratio of water and surfactant. Self-assembled cubosomes act like an active drug delivery system. They are having rheology like a solid. Cubosomes are thermodynamically stable, and their dispersions are biocompatible as well as bio-adhesive. Cubosomes are administrable in various ways, like parenteral, oral, mucosal, transdermal, etc., for the treatment of skin, hair, or any other body tissues. Cubosomes could encapsulate the amphiphilic, hydrophilic, and also hydrophobic substances. Nevertheless, some researchers have been identifying the scope of cubosomes as delivery systems. They have different drug loading modalities and having high internal surface areas. Controlled release and targeting of bioactive agents are other abilities of cubosomes. They are also applicable as membrane bioreactors,...
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Posted by admin on Jan 31, 2022 in |
The ubiquitous compound 4-Hydroxy-3-methoxy cinnamic acid, also known as ferulic acid, constitute. A bioactive ingredient of many food that may offer a potential therapeutic effects useful in the treatment of cancer, diabetes, lung and cardiovascular disease. It is also effective against the disorders relative to oxidative stress, including certain neurodegenerative diseases. Ferulic acid is widely distributed in plants in either free or conjugated forms. Overall the pharmaceutical potential of ferulic acid can be attributed to its ability in scavenging free radicals. In recent years, it is also known to inhibit HNG-CoA reductase and activate glucokinase, thus contributing to the reduction of hypercholesterolemia and hyperglycemia. This review discusses the different properties of ferulic acid, establishing a relationship to several biological activities. FA is also used in a substantial amount in the food and cosmetic industries. So also, in recent years, it has been used as a cross-linking agent to manufacture edible food films. The review also discusses compound distribution, metabolism, and physiological role uses in the production of...
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Posted by admin on Jan 31, 2022 in |
Diabetes Mellitus, a chronic metabolic disorder, is prevalent all over the world nowadays. As a result, it is estimated that it can become an epidemic in some parts of the world soon. The number of affected people could be as double as that of the currently affected patients till the next decade. In order to fulfill the increasing demands of newer, safer, and more effective medications for treatment, prevention, diagnosis, and mitigation of this condition, companies all over the world are trying to introduce new medications in the market. Before entering the market, any new drug undergoes several clinical trials and tests to check and ensure its safety and efficacy. All the associated Adverse Drug Reactions are supervised and monitored by Pharmacovigilance Centers. This ensures that the patients receive safe and effective treatment with minimum or no undesired effects. A brief overview of commonly used hypoglycemic agents and their associated ADRs obtained from publishing data is elucidated in this...
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Posted by admin on Jan 31, 2022 in |
In the recent advancement of the food and pharmaceutical industry, the encapsulation process has gained interest in the production of functional food and the sustained release of drugs to the target site. The designing and the fabrication of micro or nanocapsule has become the active field of research over the few decades. Encapsulation increases the shelf life of the bioactive materials, increases their stability and protects the bio-actives from the harsh environment. Therefore, the encapsulation process has a great potentiality in the development of functional food and drugs. Many bioactive materials, oils, probiotics, and drugs are encapsulated in a microcapsule made up of varieties of polymeric and non-polymeric substances. Successful encapsulation of materials depends on the choice of the wall materials and the correct techniques adopted for the formation of the microsphere. In this review, an attempt has been made to discuss the different materials and the techniques used in the encapsulation process with reference to the food and pharmaceutical...
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Posted by admin on Jan 31, 2022 in |
Although the human eye has multiple physical and chemical barriers to save itself from foreign materials, there are certain times when an attack on the ocular surface may lead to trauma and/or growth of microbial flora, which can be proved lethal if left untreated. However, certain allopathic treatments and therapies are available; still, there is an increased need for herbal medicines because they have lesser side effects and effective therapeutic value. This review paper identifies different types of ocular infections, how to differentiate between them through signs and symptoms, and different types of herbs used for ocular...
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