Posted by admin on Jan 31, 2020 in |
Capparis moonii wight is a large woody climber or shrub (locally known as Rudanti) having Rasayana (rejuvenating) actions and it is being used in respiratory diseases like cough, bronchial asthma and pulmonary tuberculosis by ayurvedic physicians. It is one of the drugs which have references for its use from centuries but still not much explored in this contemporary era. The review aims to provide a critical and comprehensive evaluation, from the ancient times to our days, of the ethnological, botanical, chemical and pharmacological aspects of Capparis moonii, with a vision for promoting further pharmaceutical research to explore its complete potential as a therapeutic agent. This study was performed by reviewing in extensive details the studies on historical significance and ethnopharmacological applications of Capparis moonii by using classical ayurvedic texts, international scientific databases, books, etc. In addition, the plant taxonomy was validated using certified databases such as Medicinal Plant Names Services (MPNS) and the plant list. A detailed comparative analysis of the available sources for Capparis moonii wight confirmed that...
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Posted by admin on Dec 31, 2019 in |
The fungus candida with over 355 species is an anamorphic yeast. It consists of over 20 human pathogenic species which are the cause of candidiasis. Candidiasis encompasses infections that range from superficial, such as oral thrush and vaginitis, to systematic and potentially life-threatening diseases. Candida species are opportunistic human pathogens which despite treatment with antifungal drugs can cause fatal infections in immune-compromised and immune-deficient patients. C. albicans, C. glabrata, C. tropicalis and C. parapsilosis, together account for about 95% of identifiable Candida infections. C. albicans, considered to be the most serious cause of candidiasis, is a diploid, polymorphic yeast producing three morphologic forms: yeast cells, pseudohyphae, and true hyphae. This phenotypic switching plays a vital role in virulence. Since invasive yeast infections are associated with high levels of morbidity and mortality so rapid and accurate identification can contribute to successful therapy, earlier resolution of infections and subsequent reduction of moribund outcomes. CHROM agar candida, a type of chromogenic medium, based on species-specific enzyme activity, has been found to be...
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Posted by admin on Dec 31, 2019 in |
Phytase catalyzes the formation and release of inorganic phosphate from phytic acid. A few monogastric animals that lack phytase is incapable of digesting phytate obtained from plants and gets excreted, which results in the accumulation of phosphorus in the form of phytate in the environment which has a detrimental effect. In order to combat this problem, researchers have focused on production and purification of phytase from different microbial sources, which converts phytate to useful form of phosphorous that facilitates plant growth. This review paper summaries the various methods adopted for isolation, production, and purification of phytases from various...
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Posted by admin on Dec 31, 2019 in |
Bacteria predominantly remain in a self-produced polymeric matrix, adherent to an inert or living surface. This microenvironment community of bacteria is known as biofilm. Commonly visualized as a slimy layer, a number of unique features distinguish biofilms from their planktonic counterparts. Formation of biofilms depends on the extracellular signals, mechanical, biochemical, environmental conditions and genetic factors in bacteria. The attachment of biofilms is an intriguing process which is regulated by several characteristics such as substratum, cell surface, and growth medium. These biofilms cause various infections and are of at most importance when concerned about public health. One of the challenges faced during antibacterial drug development is to create compounds to counter-attack the biofilm infections. In this study, antibiofilm activities of five essential oils (EUGENOL; CINNAMALDEHYDE; PIPERIDINE; LIMONENE) were discussed. This review consisting of explicit evidence proved that plants are indeed a wonderful source to provide naturally occurring compounds for development of therapeutic and preventive agents against infections caused by...
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Posted by admin on Dec 31, 2019 in |
Depression is a common heterogeneous, debilitating and life-threatening mood disorder affecting different segments of the community. Several chemical and synthetic medicines as standard are being employed to treat depression and may lead to complete recovery in only 50% of clinically depressed patients but causes many adverse effects. Thus, scientists are increasing their interest in research towards the utility of medicinal plants for antidepressant activity. Several medicinal plants and its derived medicinal products have been reported to exert antidepressant action in different animal models by the combined effect of their phytoconstituents. In the brain, the alteration in level of various endogenous molecules likes noradrenaline (NA), acetylcholine (Ach), serotonin (5-HT), dopamine, glucocorticoid, γ-aminobutyric acid (GABA), corticotrophin-releasing hormone (CRH) and hippocampal volume are responsible for depression. Therefore, most medicinal plants through synaptic regulation of serotonin, noradrenaline, and dopamine, overcome the altered level of monoamines in the brain and also reinforcing antioxidant defense mechanism, regulate hypothalamic-pituitary-adrenal axis activity and reducing inflammatory mediators. So, herbal medicines are widely used in contrast to allopathic or...
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