Posted by admin on Mar 1, 2016 in |
Plants have been one of the important sources of medicines since the beginning of human civilization. There is a growing demand for plant based medicines, health products, pharmaceuticals, food supplements, cosmetics etc. A review of chemical constituents present in various parts of Tinospora cordifolia and their pharmacological actions is given in the present article. Tinospora cordifolia, is a commonly used shrub in Ayurvedic medicine. Although the review articles on this plant are already published, this review article is presented to comply all the updated information on its phytochemical and pharmacological activities, which were performed by widely different methods. The notable medicinal properties are anti-diabetic, anti-spasmodic, anti-malarial, anti-inflammatory, anti-arthritic, anti-oxidant, anti-allergic, anti-stress, anti-leprotic, hepatoprotective, immunmodulatory & anti-neoplastic...
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Posted by admin on Mar 1, 2016 in |
The northeast region of India, considered as ‘hot spot’ of biodiversity, having unique ecological environment with hot and high-humidity conditions, has given rise to the world’s hottest chilli, ‘Bhut jolokia or Bih jolokia’, which is at least two times hotter than Red Savina Habanero in terms of Scoville heat units (SHU). The Assamese word “bhut” refers to the typical large pod size of the plant, while the term “bih” means “poison” indicating the high hotness in the fruits of the plant. It is extensively grown in North Eastern region of India, predominantly in the states of Assam, Nagaland, Manipur and Mizoram since ancient time. The main pungency principle of Bhut jolokia (Capsicum chinense Jacq.) is capsaicin (8-methyl-N-vanillyl-6-nonenamide) and its analogs collectively known as capsaicinoids synthesized in the epidermal cells of placenta of the fruit, and possesses anti-inflammatory and antioxidant activities. This review gives an update mainly on the pharmacological activities of Bhut jolokia (Capsicum Chinense Jaqc.), benefits and toxicity of...
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Posted by admin on Jan 31, 2016 in |
Pulsatile drug delivery systems (PDDS) have attracted attraction because of their multiple release system. Pulsatile drug delivery systems are the new approach to overcome patient non-compliance over commercially used dosage forms. These techniques also help in treating the disorders based on circadian paradigm and the drugs are rapidly released according to the lag time decided by the carrier medium. This review covers different techniques of pulsatile drug delivery system and their marketed products. Biological rhythms play a pivot role in tolerance of any medicine given for the treatment of any disorder. This system enables the active drug for target action and inflated bioavailability with increased pharmacokinetics as well as pharmacodynamics profile of active moiety. The present review state diseases wherein pulsatile drug delivery systems are promising include asthma, peptic ulcers, cardiovascular ailments, arthritis and attention deficit syndrome in children and hypercholesterolemia. The author attracts attention of pulsatile drug delivery technique in Medical and for establishment in Pharmaceutical field...
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Posted by admin on Jan 31, 2016 in |
Fluoroquinolones are the most commonly prescribed synthetic antibacterial agents having improved pharmacokinetic properties and broad spectrum of activity. Due to their broad clinical activity they are the most promising drug for antibacterial chemotherapy. The current study focused on the application of similar chromatographic system for the analysis of a number of fluoroquinolones from bulk, pharmaceutical formulations and biological matrices. We have also summarized how a single chromatographic system can be used for the quantification of a number of fluoroquinoloes from their respective marketed formulation. A detailed systemic survey of the sample preparation techniques, the chromatographic conditions and detection of the respective fluoroquinolones has been presented in this study. In the course of this discussion the advantages and applicability of the high performance liquid chromatographic techniques are also...
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Posted by admin on Jan 31, 2016 in |
The abnormal growth of White Blood Cell in the bloods and bone marrow is called as Leukaemia. Leukaemia is the 11th most common cancer worldwide. Leukaemia is not a new disease for Ayurveda, which is mentioned under the heading of Raktarbud respectively. The mutations of any carcinogens are the first causative factor of abnormal growth of cancerous cell including Leukaemia. Accordingly to Ayurveda mithya aahar-vihar is a cause of Rakta Arbud. There are so many carcinogenic agent like Benzene and Pesticide are found in diet, which cause Leukaemia. Anaemia and bleeding tendency along with its complication, Splenomegaly, Hepatomegaly these are some clinical features of Rakta Arbud mentioned in Ayurveda, which is similar to Leukaemia. Trividhparikshan mentioned in Ayurveda a unique method which will help to diagnose the patients of any disease including Leukaemia. Though there is, no basic line of treatment of Leukaemia has found in Ayurveda. Some Raktarbudnashak herbs like Lochnera rosea, Semecarpusana cardium, Urginea indica, podophyllum hexeandrum and Commiphora mukul has mentioned. Certain poly herbal and herbomineral...
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