Posted by admin on Jun 1, 2014 in |
Nanotechnology plays an important role in advanced biology and medicine research particularly in the development of potential site-specific delivery systems with lower drug toxicity and greater efficiency. In terms of nanopharmaceutics, gelatin was already considered as interesting biodegradable base material in the early days of particle development. The interest was based on the facts that gelatin has been known for its low immunogenicity for many years and is administered intravenously since it is an ingredient of various registered blood substitutes. One advantage offered by the amino acid side-chains of the gelatin matrix molecule is the option of multiple further modifications. Therefore, gelatin nanoparticles can be used as a great carrier for the drugs delivery intravenously with few surface...
Read More
Posted by admin on Jun 1, 2014 in |
Withania somnifera belongs to the Solanaceaefamily, commonly known as Ashwagandha, Indian ginseng or Winter cherry. It is an important commercial medicinal crop, considered as similar to Panax ginseng in Chinese medicine. Different parts of this plant are used in traditional medicine for the treatment of various ailments. It provides defense against diseases, adverse environmental factors and helps to retard the aging process. Ashwagandha exhibits a wide range of therapeutic properties by tuning the endocrine, cardiopulmonary, central nervous system and sexual behavior without any toxicity. The root has been used most frequently for therapeutic uses and is a constituent of over 200 formulations in Ayurveda, Siddha and Unani medicines. There are several reports to establish its immunomodulatory, anti-inflammatory, antistress, memory enhancing, antiparkinsonian, hypolipidemic, antibacterial, cardiovascular, antioxidant, antitumor and adaptogenic properties. These properties stem from the characteristic bioactive phytochemicals such as alkaloids and phytosterols present in the plant. This review presents a detailed survey on various traditional uses, phytochemical composition and pharmacological properties of Withania...
Read More
Posted by admin on Jun 1, 2014 in |
Cassia fistula Linn. (Family: Caesalpinaceae), commonly known ‘Sonali’ or ‘Bandarlati’, has been used in different traditional system of medicines for various ailments since ancient times. Cassia fistula grows throughout in Bangladesh and in many other Asian countries such as India, China, Hong Kong, Philippines, Malaysia, Indonesia, and Thailand. This article aims to provide a comprehensive review on the phytochemical and pharmacological aspects of Cassia fistula. In traditional medicine, it has been used in the treatment of diabetes, hematemesis, leucoderma, pruritis, intestinal disorder and as antipyretics, analgesic and laxative. The fruits, stem bark, and leaves of this plant contain a variety of biologically active compounds such as anthraquinones, flavonoids, flavon-3-ol derivatives, alkaloid, glycosides, tannin, saponin, terpenoids, reducing sugar and steroids those have various medicinal properties. The fruit and stem bark extract shows various activities like antipyretic, anti-inflammatory, antioxidant, antidiabetic, hypolipidemic, hepato-protective, antimicrobial, antitumor, antiulcer etc. The article reviews the various activities of the...
Read More
Posted by admin on Jun 1, 2014 in |
An ideal wound Dressing need to be redefined based on the nature of wound and wound classifications. Since generations, wound have been defined as self-healing process, but chronic wounds and other wound requires handling and care from different parameters like moist conditions, biocompatibility, microbial infection to mention a few. Traditional methods have been continuously worked upon to deliver better products. Starting from simple gauze dressings in 1900’s to bioactive dressings till today have been worked upon. Bioactive dressings based on different materials sodium alginate, chitosan, hydrocolloid, iodine has been covered in this review. Based on wounds different classifications of type of wounds, correlation of wounds with wound dressing have also been focussed upon. This has led to development of interactive dressings which are further developed as per wound requirement viz. semipermeable and hydrogel dressings. Efforts are in process to develop superabsorbing and bioactive material for critical wound care. The conventional primary and secondary dressings have been replaced by composite dressings composed by 4 to 5 layers with super absorbing...
Read More
Posted by admin on May 1, 2014 in |
This overview firstly highlights biology of endophytic microbes from medicinal plants as well as their chemistry with emphasis on the important merging of microbiology and natural products chemistry and its role in improving our current knowledge of endophytic associations in medicinal plants. Secondary metabolites of medicinal plants-derived endophytes reported in recent years are grouped according to their bioactive properties including antitumor, antimicrobial, growth-promoting, antioxidant, antithrombotic, insecticide and other functions. New insights on distributing characteristics and biodiversity of these endophytes including bacteria, actinomycetes and fungi are also presented. It suggested that endophytic microbe from medicinal plant is a treasure trove of bioactive natural products with a good and potential application prospect in pharmacy and...
Read More
