Posted by admin on Aug 1, 2011 in |
Solid dispersions is an efficient means of improving the dissolution rate and hence the bioavailability of a range of poorly soluble drugs. This article reviews the various types of solid dispersion, preparation techniques for solid dispersion and compiles some of the recent technologies. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of carrier and methods of physicochemical characterization, along with nature of drugs in solid dispersions are also discussed. Finally, limited commercialization of solid dispersions and recent revival has been...
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Posted by admin on Aug 1, 2011 in |
Many plants are essential in human health care, both in self-medication and in national services. India has a great wealth of various naturally occurring plant drugs which have great potential pharmacological activities. A number of medicinal plants are used as rejuvenators as well as for treating various disease conditions. Cedrus deodara, the common cedar is an important plant belonging to the family pinaceae. C. deodara has been proven to have great pharmacological potential with a great utility and usage as folklore medicine. This review summarized the plant characteristics with chemical composition and their pharmacological activities. This is the first article reported in this review form about C. Deodar which is benefits for science students who involved in modern health...
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Posted by admin on Aug 1, 2011 in |
Pregnancy is a state of double danger i.e. any drug that a pregnant woman takes can easily cross placenta and can produce a teratogenic effects on fetus. It can interfere with normal embryonic or fetal development and induce abnormal post natal structure or function. Teratogens alter the genetic function of fetus. This review provides practitioners with summary of information regarding teratology risks for drugs, chemical exposure during...
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Posted by admin on Aug 1, 2011 in |
The present article is a descriptive study of the performances of ethosomes and proniosomes as specialized delivery systems for transdermal drug delivery system. Vesicular systems, such as ethosomes and proniosomes are used in cosmetic and pharmaceutical products to encapsulate ingredients, to protect ingredients from degradation, to increase bioavailability, and to improve cosmetic performance. A review of literature is presented here and a sincere attempt has been made to highlight the properties and characteristics of proniosomes and ethosomes in transdermal drug delivery and cosmetic/cosmeceuticals applications. Interaction studies between proniosomes and ethosomes components and skin is also discussed along with the formulation aspects of proniosomes and ethosomes formulation. Our aim is to introduce and explore proniosome and ethosomes as a carrier system for various applications of drugs and cosmeceuticals. The goal of this study is to investigate the efficiency of transcellular delivery of drugs with the help of ethosomes and...
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Posted by admin on Aug 1, 2011 in |
Melatonin, a pineal hormone is known to regulate rhythmic behavior of mammals. Its ubiquitous presence, established recently has brought into focus several health-promoting benefits of this molecule. However, till date, melatonin has been less utilized from its nutraceutical and functional point of view. This paper reviews the chemistry, chemical synthesis, metabolism of melatonin; its sources including its bioavailability from the same, its role in mammals and in plants and the analytical techniques for quantitative analysis of the same. The nutraceutical potential of melatonin and its functional properties have been elaborated. Melatonin’s function as a direct free radical scavenger endows it the potency to act as strong antioxidants- a property which needs to be further researched upon to establish its efficacy in food...
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