Posted by admin on Nov 1, 2010 in |
Cancer is a genetic disease. The main causes of cancer are alterations of DNA, mutations, damage etc. Any herbs which may be a plant or a part of the plant that are used to maintain the health are called Herbal supplements or Phytomedicines. Plant extracts are generally prepared by boiling the herb in water. The goals of these herbal medicines include prevention and protection against cancer. The traditional plants like Eleutherococcus senticosis, Astralagaus membranaceous, and medicinal mushrooms are used in cancer treatment. The other herbs used in other parts of the world are Valeriana, Garlic, Curcumin etc. These herbal medicines along with benefits also include some adverse effects. This review summarizes the role of some pharmaceutically important herbal medicines used in treating...
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Posted by admin on Oct 1, 2010 in |
The Western Ghats of Kerala is famous for its medicinal plant wealth and the tradition of indigenous system of therapy, specifically the Ayurveda. Dasapushpam constitute a group of ten potential herbs which are culturally and medicinally significant to the people of Kerala in India. They are a group of ten herbs with which the ladies decorate their hairs and dance the Thiruvathira Kali on the day of Thiruvathira in the Malayalam month of Dhanu. These plants are therapeutically very active for various diseases and ailments. Many of them are traditionally used from time immemorial. Some of them are scientifically validated for various bioactivities. Still there are lots of possibilities for potential pharmacological activities from these herbs, yet to be explored. This article would give an insight of these ten sacred plants and their properties to further popularise these...
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Posted by admin on Oct 1, 2010 in |
The objective of the project is to develop a comprehensive database of Nuclear Receptor (NR) Superfamily-Ligand. Nuclear Receptor Superfamily represents one of the most important families of drug targets in pharmaceutical development. Nuclear Receptor) Superfamily-Ligand is a novel public NR-related chemical genomic database that is primarily focused on the correlation of information between NRs and their ligands. It provides correlation data between NRs and their ligands, along with chemical information on ligands, as well as access information to the various web databases regarding NRs. These data are connected with each other in a relational database, allowing users in the field of NR-related drug discovery to easily retrieve such information from either biological or chemical starting points. NR Superfamily-ligand database includes structure similarity search functions for the NRs and for their ligands. Thus database can provide correlation maps linking the searched homologous NRs (or ligands) with their ligands; we can gain more detailed knowledge about their interactions and improve drug design efforts by focusing on inferred candidates for NR-specific drugs....
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Posted by admin on Oct 1, 2010 in |
Aseptic processing is a widely used technology in the field of pharmaceutical, biotech, and medical device industries for the preparation of sterile materials. The term aseptic processing as it is applied in the pharmaceutical industry refers to the assembly of sterilized components and product in a specialized clean environment. Aseptic processes are some of the most difficult processes to conduct in the pharmaceutical industry. Because of the nature of aseptic processes, sterile products produced aseptically present a significantly higher risk to the patient than terminally sterilized products. Because of the high level of risk, an effective quality risk management program is necessary to protect the patient. An effective risk-management program aids in the careful control of the process, reducing the risk of contamination as well as wasted effort in controlling insignificant...
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Posted by admin on Oct 1, 2010 in |
Over the past two decades, intranasal drug delivery has shown tremendous promise for systemic delivery of therapeutic agents, although the potential of the nose as a route of administration has been known since ancient time. Psychotropic and hallucinogenic agents have been used as snuff in many parts of the world for hundreds of years. Because of rich vasculature and highly permeable structure, nasal route could be used as an alternative to parenteral routes of delivery. Nasal route circumvents hepatic first pass metabolism and gut wall enzyme mediated degradation. Nasal route is easily accessible for self-administration without the help of health professionals, and no needle stick hazards are associated with nasal administration. Other advantages of nasal drug delivery systems include rapid onset of action, reduced risk of overdose and improved patient compliance. However, there are several disadvantages of nasal route of administration including impermeability of nasal mucosa to lipophillic and high molecular weight drugs, mucotoxicity associated with long term use of formulation, requirement of expensive delivery device, and dose...
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