Posted by admin on Sep 30, 2023 in |
Nanotechnology has found its way into most science fields at a tiny scale. Particle of this size and molecules were found to work differently and got diverse applications. Novel drug delivery system leads to the development of Nanocarriers, including Nanoparticles, Nanospheres, Nano capsules, Nano emulsion, liposomes, and Niosomes. The major area for research is to design Nanoparticles that can efficiently manage particle size, surface properties, and drug release. For this to get characterizations of Nanoparticles, it is critical to control their desired in-vitro and in-vivo behavior. Nanoparticles are characterized by their size, surface morphology, and surface charge, using highly advanced microscopic techniques. Colloidal stability is ascertained through zeta potential. Nanoparticles are also characterized by polymer and drug interaction. In-vivo characterization for binding and internalization of targeted carriers to the specific cell and bio distribution study of targeted Nanoparticles could also be confirmed using confocal microscopy. This review covers all the aspects related to the characterization of the pharmaceutical...
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Posted by admin on Sep 30, 2023 in |
In this advanced technological world, the computer has become an indispensable piece of equipment in both office and home. Visual and ocular problems have recently been reported as the most frequently occurring health problem among computer users. Prolonged exposure to radiofrequency radiation affects eyesight and indirectly affects the whole body function. The herbal supplements that improve eye vision are more effective for all age groups and those involved in jobs that cause strain over the eye. Computer Vision Syndrome (CVS) is caused by extensive computer use that reduces eye blinking rate. CVS comprises symptoms like dry eye disease, strain, redness, and irritation. Sight promoters relieve strain, and energize eyes to keep it healthy. They protect and enhance the vision. In Siddha, many herbs and day-to-day disciplines are advised to maintain good vision. This review article discusses the herbs and other disciplines to be followed that will be helpful in the prevention and management of...
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Posted by admin on Sep 30, 2023 in |
Parkinson’s disease (PD) is a common neurodegenerative disorder that affects approximately 2% of the population aged over 65. Dopamine precursor L-3,4-dihydroxyphenylalanine (L-DOPA) is the main treatment to provide symptomatic relief for Parkinson’s disease (PD). However, with long-term administration of L-DOPA, as many as 95% of patients develop several complications. Medicinal plants (MP) and their active components have been used throughout the worldfor the management and treatment of several diseases such as PD. The World Health Organization (WHO) estimates that 80% of population in developing countries, particularly in Africa, use traditional medicine due to financial constraints. Thus, the use of medicinal plants represents the therapeutic response for populations who have difficulty accessing modern drugs and a source of income. Several MP have been administered over a long period, and they have been proven to cure PD. Therefore, this review provides a summary of recent advance of MPand their bioactive compounds involved in the treatment of PD from the year 2018up to...
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Posted by admin on Aug 31, 2023 in |
Thrombosis is one of the major causes of death and disability worldwide. Cancer patients are commonly thrombophilia or prothrombotic since they have abnormalities in all three factors of Virchow’s triad, which lead to thromboembolism. Venous thrombosis (VT) is a chronic disorder that has the potential to be fatal and cause considerable complications. Venous thromboembolism (VTE) may potentially be the first indication of an undetected cancer in individuals. The rate of VTE and the risk of complications are much higher in the cancer patient groups. Arterial thrombosis is more likely to form when the plaque on the wall of the arteries consists a significant quantity of lipids covered by a layer of connective tissue. Thrombus formation in arteries may result in a heart attack or stroke. The hemostasis phase (liquid blood quickly hardens and forms a clot following injury to the blood vessel wall) spirals out of control. As a result, many blood clots form in the blood vessels that provide blood to various organs. Patients display paradoxically both excessive...
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Posted by admin on Aug 31, 2023 in |
Oral route is the easiest and most convenient route for drug administration more than 40% of new chemical entities exhibit poor aqueous solubility, resulting in unsatisfactory oral drug delivery. Self-nano-emulsifying drug-delivery systems (SNEDDSs) are one of the emerging strategies developed to tackle the issues associated with their oral delivery. SNEDDSs are composed of an oil phase, surfactant, and cosurfactant or cosolvent. SNEDDSs characteristics, their ability to dissolve a drug, and in-vivo considerations are determinant factors in the choice of SNEDDSs excipients. SNEDDS is a proven method for enhancing solubility and bioavailability of lipophilic compounds. Considering the ease of large-scale production and the robustness of SNEDDS, several formulations techniques are commercially available. The review provides exhaustive insight about the potential of SNEDDS in improving bioavailability of poorly soluble...
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