Posted by admin on Jan 31, 2023 in |
Compounds with heterocyclic moiety are important for life and are abundant in nature. Heterocyclic compounds have a crucial part in the metabolism of all biological cells. Humanity relies heavily on nitrogen-based heterocyclic compounds. Benzimidazole, in particular, is a vital component of the entire nitrogen-based heterocyclic chemical family, not just physiologically but also industrially. Because once benzene, as well as imidazole, get merged around each other, a heterocyclic benzimidazole compound forms. Benzimidazole incorporates two nitrogens like a heteroatom. Benzimidazole analogues are often more powerful, medicinally significant chemicals with a wide range of biological activities. Benzimidazole analogues have been proven to be beneficial in several fields. The medicinal characteristics of benzimidazole analogue are diverse, including anticancer, antidiabetic, antihypertensive, and antimicrobial properties. Because of the medications’ uses in the treatment of microbe-related infections and other biological activities, stronger and more significant pharmaceuticals are being developed. These compounds have been found to be efficient against various bacteria in pharmacological tests. The antimicrobial property of several benzimidazole compounds is summarised in this...
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Posted by admin on Jan 31, 2023 in |
Neuropathic pain is a chronic illness that originates when abnormal functioning in the nervous system is observed or if the nervous system, including peripheral nerves, spinal cords, and brain, is damaged or not working properly, and originating pain. Therefore, it can be said that neuropathic pain is a chronic illness that directly impacts a large number of patients, society, and healthcare systems all over the world. The prevalence of neuropathic pain is believed to be 7-8% in the general population, and it is supposed to rise in the future. The impact of neuropathic pain on older persons is significant. The medical practitioner faces a problem in reducing neuropathic pain symptoms and improving the patient’s quality of life. Older people are easily and badly affected by neuropathic pain and are more susceptible to specific adverse effects. Neuropathic pain is different from nociceptive pain, and there is a requirement for a different treatment strategy for neuropathic pain management. The present review article is based on a detailed literature survey on etiology,...
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Posted by admin on Jan 31, 2023 in |
Introduction: Gold preparations are highly prized and often utilized for their tonic and revitalizing effects in Indian systems of medicine. Gold has both preventive and curative medicinal properties. The Kashyap Samhita, under the name Swarnaprashana, describes the usage of gold internally in children via the oral route. After birth, it is indicated in Lehan karma (supplementary feeding to improve nutrition, immunity and intelligence) and Jatkarma (newborn care). Now a day Swarnaprashana in children is getting huge publicity, and many trials are being conducted to evidence its use in children. Material and Methods: This review is in a narrative format and consists of all publications relevant to Swarnaprashana or Swarnabinduprashana, Suvarnabindu prashan, Suvarnavachayog, or Swarnavachayog that the authors identified through a systematic search of major computerized medical databases; no statistical pooling of results or evaluation of the quality of the studies was performed due to the widely different methods employed by each study. Result and Discussion: The present review of the studies proves the role of Swarnaprashana in enhancing cognition...
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Posted by admin on Jan 31, 2023 in |
Cardiovascular disease (CVD) is the sixth most common human disease that causes about 17.3 million deaths yearly. Advancement in nanomedicine enables the usage of nanomaterials for treating cardiac disorders. Among these, Cerium Oxide (CeO2) nanoparticle is gaining attention due to their irreversible oxidative states (Ce3+ and Ce4+), which provide them with many unique, physiologically important traits like antioxidant property, Anti-inflammatory property, free radicle scavenging potential etc. All these features make CeO2 an excellent agent for treating many cardiac related disorders. We have used the search engines PubMed and Google scholar to identify the relevant papers in last 5 years on this topic. Some old classical articles were also identified, and the review was written based on these relevant papers. Cerium nanoparticles (CeNPs) are being used in the therapy of CVD mainly for reducing oxidative stress, inflammation, and damage caused by free radicals. CeO2 can also protect endothelial cells (ECs) from apoptosis. It can be used as a wound-healing agent during cardiac surgeries. This is because of its potential to...
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Posted by admin on Jan 31, 2023 in |
The review briefs the information mainly about migraine disease. It tells about genes that are responsible for migraine. Alternating Hemiplegia in Childhood, Cortical spreading depression, Monogenic Migraine, Hemicrania Ophthalmoplegia, Hemicrania Alia Definite, Hemicrania, Complicated Migraine, Status Migrinous these are types of migraine, sign and symptoms also included. The history gives all the information of scientists researching the migraine disease. Ketone bodies like D-β-hydroxybutyrate, Acetoacetate, and Acetone treat migraine. Oxidative stress and Deoxyribonucleic acid damage in patients with migraine and different channel information are given. The researcher observed new mammalian TRP channels: Canonical, Vanilloid, Melastatin, Polycystic kidney illness, Mucolipin, and Ankyrin. 31P Spectroscopy is a theory in which the quality of exemplary headache is brought about by vasospasm-initiated cerebral ischemia and the migraine by the expanded cerebral bloodstream from the resulting cerebral acidosis. The important part is a dietary antioxidant, and plant antioxidants are used for migraine...
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