Posted by admin on Jul 1, 2010 in |
Herbalism is a traditional medicine practice based on the utilization of plants and plant extracts. In herbalism ‘Valerian’ is a boon medicine for several ailments. Valerian (Valerian officinalis) is a naturally occurring Ayurvedic medicine widely grown in the temperate zones of Europe, North America and Asia and is a safe herbal supplement indicated in various ailments, chief being for the symptoms associated with difficulty in sleeping. It improves subjective experiences of sleep when taken nightly over one- to two-week periods. Although the adverse effect profile and tolerability of this herb are excellent, long-term safety studies are lacking. Due to the this limitations and inconsistent results in currently published clinical trials, further research is needed to clarify the efficacy and side effect profile of valerian, especially in regard to long-term therapy. In present investigation, the medicinally important herbal drug Valerian is reviewed for various taxonomical aspects including botanical authenticity, historical backgrounds, description, existing common names, medicinally important species, going through cultivation, commerce, regulation to phytochemical description, pharmacodynamics, pharmacokinetics, adverse drug...
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Posted by admin on Jun 1, 2010 in |
Cordyceps militaris is an important medicinal mushroom useful for the extraction of several bio-metabolites for natural drugs to revitalize the various physiological systems of the body from the ancient era. The constituents of C. militaris are now using widely in the modern pharmaceutical industries. The active principles of C. militaris are beneficial to act principally as pro-sexual, anti-cancer, immunomodulatory, and anti-oxidant agent, let alone its others beneficial activities for most of the systems of the body. In addition, it has lots of clinical applications. The prospects of this novel mushroom could be used not only for modern medicinal manufacturers, but also for the community people for the betterment of their health. The present review highlights the importance of this medicinal mushroom C. militaris, also aiming to draw necessary attention of the researchers as a frontier...
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Posted by admin on Jun 1, 2010 in |
Paracetamol is an important anti-inflammatory and analgesic drug widely used in biological disorders. One of major problems with this drugs is its low solubility thus dissolution rate in biological fluid, which results into poor bioavailability after oral administration. In this study polyvinyl pyrrolidone (PVP) is used to enhance bioavailability of paracetamol. Paracetamol and PVP are used in 1:1 and 1:2 ratios to study the effect of PVP in dissolution profile of drug. Dissolution study showed a linear increase in paracetamol release with increase in polymer concentration. Two different batches of granules are also evaluated for their micromeritics properties and flow behavior. The micromeritics properties and dissolution profile showed a evident that PVP can be used to improve dissolution behavior of...
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Posted by admin on Jun 1, 2010 in |
Barberries are a large group of evergreen shrubs, found in Lalitpur, Allahabad, Bhopal and Haldwani etc. It is an evergreen shrub. Commonly, its fruits are called as berries. This plant is generally use in case of diabetes and mouth ulcer, as a traditional use. Type 2 diabetes mellitus (formerly called NIDDM, type II or adult-onset) is characterized by insulin resistance in peripheral tissue and an insulin secretory defect of the β- cell. This is the most common form of diabetes mellitus and is highly associated with a family history of...
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Posted by admin on Jun 1, 2010 in |
Psoralia corylifolia commonly known as Babchi, Bavachi in Hindi, is a well known herb in Indian system of medicine to treat various disorders including diabetes mellitus without any scientific evidences. Therefore this study was designed to investigate in vivo hypoglycemic and antidiabetic potential of methanolic extract of seeds of Psoralia corylifolia in glucose loaded animals and alloxan induced diabetic animals. In both the models Psoralia corylifolia reduced the blood glucose level when compared to diabetic control group and exert a significant hypoglycemic and antidiabetic activity. However the potency of the herb was less than that of standard drug metformin. Psoralia corylifolia methanolic extract also reversed the body weight in normal and alloxan induced diabetic animals. The results of this study revealed the presence of a significant antidiabetic potential of methanolic extract of Psoralia corylifolia in alloxan induced diabetic rats. On the basis of this further research work is needed to investigate exact mechanism of action and also to isolate the active constituent/s responsible for the...
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