Posted by admin on Aug 31, 2022 in |
COVID-19 is a disease caused by SARS-CoV-2 that can trigger respiratory tract infection. Due to its tendency to affect the upper respiratory tract (sinuses, nose and throat) or lower respiratory tract (windpipe and lungs), this disease is life-threatening and affects a large number of populations. This virus’s unique and complex nature enhances the scope to look into the direction of herbal plants and their constituents for its prevention and treatment. The herbal remedies can have preventive as well as therapeutic actions. This review focuses on various aspects of using herbal medicines for COVID-19, as herbal constituents may also have adverse effects. Various studies revealed that some medicinal plants show life-threatening adverse effects, so selecting plants, and their related studies should be appropriate and strategic. This article includes various factors that should be considered before herbal drug use in COVID-19 patients. These are clinical trials, safety, molecular mechanism, and self-medication, which have been elaborated. This article also discusses the targets of covid-19 and different coronavirus strains. As before, treatment diagnosis...
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Posted by admin on Aug 31, 2022 in |
3D printing is an emerging technological advancement that could be applied in several medical fields, the educational arena, and preoperative planning. 3D printing technology, also known as additive manufacturing, is significant as it is cost-effective compared to traditional cadaveric models. The purpose of writing the current review on 3D printing techniques was to compile the recent literature with a special focus on the methods, principles, and fabrication mechanisms to generate 3D printed models. The novel technology is reliable and appropriate for analyzing congenital heart diseases, but 3D printing has limitations and potential bias about subjectivity in the modernization of treatment for congestive heart diseases. 3D models can serve as a summary of diagnosis and a reliable tool for the choice of disease treatment. Albeit, high-resolution 3D printing methods are still in the initial stage of development with limitations, they demonstrate a huge potential to manufacture multi-functional materials. The present review briefly explains the applications, limitations, and regulatory challenges to be overcome in the fabrication of 3D printed...
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Posted by admin on Aug 31, 2022 in |
December 2019 has become one of the most surprising days in the whole world in light of the flare-up of a most infectious sickness brought about by novel Covid or Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2). This study is conducted to assess the benefits of the use of home remedies to prevent the cause of Covid-19 and evaluate the assessment of dietary changes and physical activity in the prevention of Covid-19. A questionnaire-based online survey is conducted using Google forms consisting of multiple-choice questions about home remedies, lifestyle and dietary changes made by the people during this pandemic. These home remedies included using different types of herbal preparations, steam inhalation, physical exercise and OTC medications for prophylaxis. Questions likewise included about being infected by Coronavirus-19(during first wave or second) and their recovery period, additionally collected their viewpoint for changes made, for example how much they are useful in the prevention of the attack and whenever encountered any undesirable impacts. Total responses were 210, among which 121(57.6%) responses...
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Posted by admin on Aug 31, 2022 in |
The purpose of the current research was to formulate and evaluate patient-friendly allopurinol solid dispersion based fast-dissolving tablets using a sublimation technique in order to accomplish rapid drug dissolution. In the present study, an effort was made to fasten the release of allopurinol from oral tablet dosage form by the conversion of the drug into solid dispersion form followed by further incorporation of allopurinol solid dispersions with superdisintegrants and camphor/ammonium bicarbonate as the subliming agents. The prepared fast-dissolving tablets of allopurinol solid dispersion were analyzed for pre-compression and post-compression parameters. Based on the results obtained for in-vitro drug release studies, it was observed that the formulation F8 showed a fast release profile of about 99.51% in 30 min and a disintegration time 40 sec in comparison with other formulations. The initial dissolution rate was 34.25% / 10 min for the best formulation, F8. FT-IR studies disclosed that there were no interactions between drugs and excipients. The current investigation revealed the potential for the rapid dissolution of allopurinol solid dispersion...
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Posted by admin on Aug 31, 2022 in |
The aim of the research work was to determine and compare the efficacy and pharmacoeconomics of Atorvastatin and Rosuvastatin. The cohort, observational, and prospective studies were conducted at KMC multispeciality hospital, Trichy. The hyperlipidemic patient was treated with Atorvastain (10 mg) and Rosuvastatin (5 mg) every day over a period of six months. Contemplating the inclusion and exclusion criteria, 104 patients were selected for the study. From the selected 104 patients, 52 patients were treated with Atorvastatin (Group- A) and Rosuvastatin (Group- B). The therapeutic effect of both drugs was compared. The level of Total cholesterol (TC), Triglyceride (TG), Low-density lipoprotein (LDL), and High-density lipoprotein (HDL) were estimated. Rosuvastatin-treated patient’s reports showed a significant reduction in total cholesterol, triglyceride, and low-density lipid-protein, and increased the high-density lipoprotein during the therapy compared to Atorvastatin treated patient’s group. The results revealed that Rosuvastatin is more effective than Atorvastatin and Rosuvastain is cost effective than...
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