Posted by admin on Jan 31, 2022 in |
Although the human eye has multiple physical and chemical barriers to save itself from foreign materials, there are certain times when an attack on the ocular surface may lead to trauma and/or growth of microbial flora, which can be proved lethal if left untreated. However, certain allopathic treatments and therapies are available; still, there is an increased need for herbal medicines because they have lesser side effects and effective therapeutic value. This review paper identifies different types of ocular infections, how to differentiate between them through signs and symptoms, and different types of herbs used for ocular...
Read More
Posted by admin on Jan 31, 2022 in |
Human Immunodeficiency Virus or HIV is generally known, is a unique type of virus (retrovirus). HIV is a slow virus that causes acquired immunodeficiency syndrome, a human condition in which the progressive failure of the immune system allows opportunistic infections and life-threatening cancers to spread. Retroviruses are a single positive susceptible RNA virus with a DNA mediator and binding parasite targeting a host cell. Retroviruses have risen to prominence in human pathology through their recent association with leukemia and acquired immunodeficiency syndrome (AIDS). This virus infects species of vertebrates ranging from fish to primates and can cause various types of malignancies, homeopathy, immune diseases, and neurodegenerative diseases. Since the Peyton Rous experimented more than 70 years ago, animal retroviruses have served as models for viral carcinogenesis, with oncogenes being discovered for the first time. The central goals of retrovirology today are the treatment and prevention of human and non-human diseases and the use of this virus in research. Recent studies have shown that retroviruses can be used in several...
Read More
Posted by admin on Jan 31, 2022 in |
Medicinal plants and their investigation towards the phytoconstituents is much interested in today’s research. The plant Achyranthes aspera Linn. is one of the most use full drugs in Siddha and Ayurvedha medicines for treating various diseases in different formulations. Here the aim of this study is to evaluate the pharmacognostic parameters and identify the phytoconstituents. A preliminary phytochemical study helps identify the phytoconstituent present in different extracts, and Column Chromatography was used to isolate the phytoconstituent principle present in the methanol extract. The structure of the isolated compound was elucidated by Spectroscopic methods like UV spectroscopy, IR spectroscopy, NMR spectroscopy, MASS spectroscopy. A yellow crystalline compound was isolated from the methanol extract of Achyranthes aspera Linn. in the fraction of Chloroform: Ethyleacetae in (80:20) ratio. From the spectroscopic method, the structure of the isolated compound was elucidated, and the proposed structure may be (E)-2-(E)-tetracos-21-enoyloxy) ethyl pentacos-22-enoate. The antimicrobial activity of the methanol and aqueous extract of Achyranthes aspera Linn. has also been screened towards bacterial and fungal organisms like...
Read More
Posted by admin on Jan 31, 2022 in |
The water extract of Ocimum gratissimum, L Lamiaceae, used in traditional medicine and local food spice, was evaluated for its ocular effect using three ocular parameters, pupil diameter (PD), corneal reflex (CR) and pupillary light reflex (PLR). The phytochemical tests were performed on the pulverized leaves, which were used to ascertain the distribution pattern of some possible bioactive agents responsible for the presumed activity of Ocimum gratissimum. It was also tested for the presence of the following: glycosides, carbohydrates, alkaloids, saponins, flavonoids, tannins and proteins, and the results show the presence of fats and oil, reducing sugar and terpenes> tannins> cyanogenic glycosides> alkaloid and steroidal aglycone, while there were no traces of anthraquinones and flavonoids. The Ocimum gratissimum water extracts caused dilatation of the pupil (3.13%), a mydriatic effect, while the corneal reflex was not abolished, showing a lack of local anesthetic property. However, the pupillary light reflex was present throughout the...
Read More
Posted by admin on Jan 31, 2022 in |
The objective of the present work is to develop and standardize the UV-Spectrophotometric method for the assessment of Bilastine in bulk and pharmaceutical dosage forms. On account of not much work being reported on the drug Bilastine and also it is a new second-generation anti-histamine molecule. Hence it is necessary in this context to relook into the older methods and further research for new methods to decide on the efficacy, cost, and selectivity of the method. The λmax of bilastine was found at 282.5 nm. Beer’s law was obeyed in the concentration range of 10-50 mg/ml. The limit of detection and limit of quantification were found to2.94 mg/ml and 8.92 mg/ml respectively. Recovery of Bilastine in tablet formulation was observed in the range of 96-105%. All the precision, repeatability, and reproducibility studies were performed, and the % RSD was found to be less than 2%. The % degradation of Bilastine by acidic, basic, oxidation, thermal and photolytic degradation was found to be 6.04, 6.97, 10.68, 9.05, 6.5%, respectively. The...
Read More
