Posted by admin on Jan 31, 2023 in |
Introduction: Gold preparations are highly prized and often utilized for their tonic and revitalizing effects in Indian systems of medicine. Gold has both preventive and curative medicinal properties. The Kashyap Samhita, under the name Swarnaprashana, describes the usage of gold internally in children via the oral route. After birth, it is indicated in Lehan karma (supplementary feeding to improve nutrition, immunity and intelligence) and Jatkarma (newborn care). Now a day Swarnaprashana in children is getting huge publicity, and many trials are being conducted to evidence its use in children. Material and Methods: This review is in a narrative format and consists of all publications relevant to Swarnaprashana or Swarnabinduprashana, Suvarnabindu prashan, Suvarnavachayog, or Swarnavachayog that the authors identified through a systematic search of major computerized medical databases; no statistical pooling of results or evaluation of the quality of the studies was performed due to the widely different methods employed by each study. Result and Discussion: The present review of the studies proves the role of Swarnaprashana in enhancing cognition...
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Posted by admin on Jan 31, 2023 in |
A novel, rapid, isocratic, reversed-phase HPLC method was developed to simultaneously determine betamethasone dipropionate, miconazole nitrate and chlorocresol in a topical dosage form. The separation was performed on the C18 prontosil (250 x 4.6mm x 5µ) column. The mobile phase used for this study consists of acetonitrile and phosphate buffer of pH 2 in the ratio of 70:30 v/v, respectively. The flow rate was set as 1 ml per minute. This method used a UV detector with a wavelength of 235 nm. The retention time of chlorocresol, miconazole nitrate, and betamethasone dipropionate was 4.30 min, 5.13min, and 6.49 min, respectively. Linearity was observed for betamethasone dipropionate, miconazole nitrate, and chlorocresol in the concentration range of 1 to 3 µg/ml, 40 to 120 µg/ml and 2 to 6 µg/ml, respectively. The novel, rapid, reversed-phase HPLC method can be used in the regular analysis of any drug or combination in the pharmaceutical dosage...
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Posted by admin on Jan 31, 2023 in |
The present study estimated the antidiabetic activity of methanolic extract of plant fruits of plant Withania coagulans L. Dunal. Withania coagulans (family Solanaceae) is commonly known as “Paneer ke phool” in Hindi and “Indian cheese maker” or “Vegetable rennet” in English, distributed in drier parts of India. The primary aim of this study was to confirm antidiabetic action of Withania coagulans by using the in-vitro method of glucose uptake by yeast cells using methanolic fruit extract of the sample. It is reported that the Withanolides are responsible for its anti-hyperglycemic activity, which has been standardized by the TLC method using 50% Sulphuric acid and dragendroff’s reagents as a spraying agent in this study. The current research found that Withania coagulans methanolic fruit extract improved glucose absorption in yeast cells by 0–90% at various glucose concentrations (5, 10, and 25 mM). Metformin was used as a standard reference. At all glucose concentrations, the highest concentration of WCME (5 mg/ml WCME) demonstrated maximum activity and showed the greatest increase (81.83 percent)...
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Posted by admin on Jan 31, 2023 in |
Cardiovascular disease (CVD) is the sixth most common human disease that causes about 17.3 million deaths yearly. Advancement in nanomedicine enables the usage of nanomaterials for treating cardiac disorders. Among these, Cerium Oxide (CeO2) nanoparticle is gaining attention due to their irreversible oxidative states (Ce3+ and Ce4+), which provide them with many unique, physiologically important traits like antioxidant property, Anti-inflammatory property, free radicle scavenging potential etc. All these features make CeO2 an excellent agent for treating many cardiac related disorders. We have used the search engines PubMed and Google scholar to identify the relevant papers in last 5 years on this topic. Some old classical articles were also identified, and the review was written based on these relevant papers. Cerium nanoparticles (CeNPs) are being used in the therapy of CVD mainly for reducing oxidative stress, inflammation, and damage caused by free radicals. CeO2 can also protect endothelial cells (ECs) from apoptosis. It can be used as a wound-healing agent during cardiac surgeries. This is because of its potential to...
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Posted by admin on Jan 31, 2023 in |
The oyster mushroom (Pleurotus ostreatus) is a culinary mushroom. Mushrooms are considered a potential source of many essential nutrients and therapeutic bioactive compounds. Pleurotus ostreatus is a macro fungus that belongs to the class Basidiomycetes and the family Pleurotaceae, known as the oyster mushroom. It is the most important commercially cultivated mushroom in the world. Mushroom contains rich nutrients such as proteins, carbohydrates, vitamins, amino acids, lipids and fibers. It is used as food and medicine. Mushroom contains more bioactive compounds such as peptides, polysaccharides, liposaccharides, glycoprotein, lectin, triterpenoid, fatty acids, essential amino acids and nucleosides. They are used traditionally as a medicine for different diseases. These mushrooms have been reported to be antioxidant, anticancer, antimicrobial, anti- inflammatory, antidiabetic, antihypertensive, antihypercholesterolemic, antiatherogenic, anti-hyperglycemic and immunomodulating. This review gives information on the traditional uses, chemical composition and nutritional benefits of oyster mushrooms. These studies reveal that Pleurotus ostreatus is a source of medicinally active compounds with various pharmacological effects. These studies will be helpful to create interest in Pleurotus ostreatus...
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