Posted by admin on Apr 30, 2022 in |
Balashosha is a disease caused by nutritional deficiencies in which the body gets slowly emaciated. This condition is very much similar to malnutrition. It reduces the baby’s growth and increases the chances of having a low birth weight and later suffering from childhood infections and mortality. In Ayurveda, Balashosha is described as Apatarpana janya vyadhi and due to Rasavaha Shrotodusti, where Kaphadosha plays an important role in the pathogenesis. Aim: Aim of this article is to evaluate the efficacy of Chaturjatadi Sambharak in the management of Malnutrition (Balashosha). Materials and Methods: A literature review was conducted with the help of many important Ayurvedic and Modern textbooks, Research papers, Journals to collect information on the content of Chaturjatadi Sambharak, an Ayurveda drug indicated for Ajeerna(indigestion), Shvasa (dyspnoea), Kasa (cough), Sarvarognashaka (cures every disease), Balya (Strength promoting), Angavardhaka (Anabolic/growth-promoting) and Pushtikaraka (promoting nutrition) in children. Conclusion: This literary review article provides evidence regarding the immunomodulatory, antimicrobial, Antioxidant activity along with Deepana (appetizer), Pachana (digestive), Krimihara (antihelminthic), Brimhana (anabolic/ growth-promoting), and Rasayana...
Read More
Posted by admin on Mar 31, 2022 in |
The present investigation screening and characterization of α-amylase and antimicrobial compound producing filamentous fungi is used for extensive commercial applications in various sectors and is highly demanded in the Biotech industry. The results reveal that out of the carbon substrates alone, sugarcane bagasse with a combination of Tween-80 was found to yield maximum α-amylase (151.76 IU) under solid-state fermentation by different species of fungal species such as KRV_001Chaetomium oryzae, KRV_002 Penicillium citrinum, KRV_003 Aspergillus flavus, KRV_004 Penicillium notatum, KRV_005 Alternaria longipes and KRV_006 Trichoderma polysporum. Among them, KRV_001 Chaetomium oryzae, KRV_002 Penicillium citrinum, KRV_005 Alternaria longipes were maximum expressed α-amylase based on the plate assay by different pH, temperature and different substrate using amylase activity, SDS-PAGE, Antimicrobial activity has been done in Methanol extract exhibited antibacterial activity against S. aureus MTCC96 whereas the water extract displayed antibacterial activity. The organism produces volatile and water-soluble antibiotics and shows significant inhibition as the potential value of KRV_001Chaetomium oryzae and little less activity of KRV_006 Trichoderma polysporum among the isolates was...
Read More
Posted by admin on Feb 28, 2022 in |
Irrational use of medicines is a major problem worldwide. In surgical patients, a greater number of drugs are prescribed So, evaluating prescribing patterns of various medications in surgical inpatients would enable identifying the presence of irrational use, thereby paving a way to rational prescribing. A prospective observational study was conducted in a secondary care hospital for six months. The general surgery, gynecology and orthopedic wards were included in the study. Descriptive statistics were used to assess drug utilization patterns and measure drug use indicators. A total of 97 patients admitted to the orthopedic, general surgery, and gynecology wards were enrolled in the study. The most commonly prescribed medications were Operation theatre (OT) medications, analgesics, Gastrointestinal tract(GIT) related medicines, antimicrobial agents (AMA), and their percentage use was 29.47%, 16.44%, 16.24%, 12.03%, respectively. Based on WHO core prescribing indicators, the average number of drugs per encounter was 15.4, the drugs prescribed from WHO-EML (World Health Organization- Essential Medicines List) were 29.87%, and the total number of prescriptions with injection was 95.8%....
Read More
Posted by admin on Feb 28, 2022 in |
The current study investigated and compared the antibacterial activity of common kitchen spices; Ginger, Turmeric, Bay leaf, and Coriander, against Escherichia coli, Staphylococcus aureus, Salmonella Typhi, and Pseudomonas aeruginosa. The antibacterial activity of different spices was calculated by the agar well cup plate method. The concentrations, 75%, 50%, and 25%, were made for all the test spices by diluting the concentrated extract with appropriate volumes of sterile distilled water. Ginger and turmeric are effective against all four pathogens. Ginger reported maximum activity against Escherichia coli with 14.5 zones of inhibition at 100% concentration. Bay leaf showed comparatively good antibacterial activity at higher concentrations and possessed maximum antibacterial activity against Salmonella Typhi with 15.4 zones of inhibition at 100% concentration. Coriander unveils comparatively good antibacterial activity against Escherichia coli and Staphylococcus Aureus at higher concentrations. It exhibits maximum antibacterial activity against Pseudomonas aeruginosa with an 18.7 mm zone of inhibition at 100% concentration. Coriander didn’t reveal activity against Salmonella Typhi at any concentration. The results of the present study are...
Read More
Posted by admin on Jan 31, 2022 in |
Recurrent aphthous Stomatitis (RAS) is a painful ulcerous condition that was conservatively treated using topical corticosteroids, immuno-suppressants, thalidomide with some potential risks and reactions. Considering this, herbal extracts are found to be a better alternative with very minimum side effects. Punica granatum (pomegranate) extract is one such flavonoid-containing food supplement with excellent antimicrobial, anti-inflammatory, and antioxidant properties used in preventing and treating RAS. The aim of the study is to assess the efficacy of Punica granatum extract in treating RAS. Materials And Method: Systematic review of randomized, clinical studies were searched using Pubmed, Scopus, Cochrane, Medline, Science direct, Lilacs, and Grey Literature. Research articles were collected using both electronic and manual search methods with a final record of nineteen. Several articles were scrutinized, redundant information was discarded, and based on the study pattern, interventions, outcomes, eight records were taken for consideration. Results: Four studies were refined in the systematic review with randomized, clinical studies meeting all criteria. These three were statistically significant and the other did not clearly state...
Read More
