Posted by admin on Nov 30, 2021 in |
This study aims to valorizeten medicinal plants traditionally used for oral care in Benin by producing scientific data on their toxicities, antimicrobial activities, and chemical properties. The ten medicinal plants (Zanthoxylum zanthoxyloides, Vitellaria paradoxa, Prosopis africana, Dialium guineense, Pseudocedrela kotschyi, Parkia biglobosa, Azadirachta indica, Diospyros mespiliformis, Anogeissus leiocarpa and Bridelia ferruginea) were identified following an ethnobotanical survey conducted in Benin. With the exception of the hydroethanolic extract of Z. zanthoxyloides, all extracts have an LC50 greater than 0.1 mg/mL, indicating that these plants are non-cytotoxic. Of the ten extracts tested, only the hydroethanolic extract of Z. zanthoxyloides stem has no activity on the bacterial strains used. The results of the antibacterial test show that the largest diameter of inhibition was obtained in the extract of A. leiocarpa on Escherichia coli ATCC 25922, a reference strain with 25.67mm. The highest levels of total flavonoids (FVT) and total polypenols (TPP) are recorded respectively in P. kotschyi (145.86±0.7 EC/gMS) and D. guineense (70.194±0.220 EGA/g Ms). The antiradical powers of the extracts with...
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Posted by admin on Nov 30, 2021 in |
The purpose of the present study was to examine the influences of roasting and the effects of roasting temperature and duration on the chemical composition of cinnamon bark oil and to extend our knowledge concerning the changes in antioxidant activity, antimicrobial activity, physical properties such as colour, refractive index, density and contents of cinnamaldehyde and other components of cinnamon bark oil. Roasted Cinnamon barks were extracted using (40-60 ºC b.p) petroleum ether. Roasting increased the oil content of the cinnamon bark significantly (P<0.05). Maximum oil yield was observed at 100°c for 10 min (10.78 ± 0.03). Analysis of the extracted aromatic oils demonstrated a significant increase in antioxidant activity, total phenolic content, antimicrobial activity, density and also a significant decrease in refractive index and colour values for roasting periods of 10 to 30 min. An increase in the amounts of cinnamaldehyde of the roasted cinnamon bark oils was also found at 1800c for 10 min. However, during roasting 8-Allyl-8-methyl-3-Oxabicyclo [4.2.0] Oct-5-ene was generated. The results obtained lead to conclude...
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Posted by admin on Oct 31, 2021 in |
Antimicrobial activity of the various species of Hibiscus like Hibiscus sabdariff, Hibiscus rosa-sinensis, Hibiscus trionum, Hibiscus cannabinus, Hibiscus mutabilis against various pathogens like Staphylococcus aureus, E. coli, Bacillus subtilis, Streptococcus species, Salmonella typhimurium, Klebsiella pneumonia, Pseudomonas aeruginosa, Serratia marcescens, were studied with the help of agar well diffusion method. The solvent extracts like Methanol, Ethanol, Chloroform, Acetone, Diethyl ether of all the samples were used to measure the antimicrobial activity by using Muller-Hinton agar plates which showed the highest zone of inhibition against Staphylococcus aureus, Pseudomonas aeruginosa. In Hibiscus sabdariff, Methanol, Chloroform, and Acetone extract showed the highest zone of inhibition against Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella pneumonia. In Hibiscus rosa-sinensis, Methanol and Acetone showed the highest zone of inhibition against Streptococcus species, Pseudomonas aeruginosa and Klebsiella pneumonia. Chloroform showed the highest zone of inhibition against Streptococcus species. In Hibiscus surattensis, Chloroform showed the highest zone of inhibition against E. coli. Methanol, Chloroform, and Acetone showed the highest zone of inhibition against Serratia marcescens. All the pathogens were...
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Posted by admin on Sep 30, 2021 in |
The present study investigates the isolation and identification of Multi-Drug Resistant bacteria from Hospital Effluent and the determination of Antimicrobial activity of Terminalia bellerica (Roxb.) against the isolated Multi Drug-Resistant Bacteria. Hospital effluent was collected and screened for the presence of Drug resistance phenotype against five different antibiotics, and the isolated bacterium was identified by 16s rRNA sequencing. Terminalia bellerica Roxb., Baheda has established antimicrobial activity against Gram-negative and Gram-positive bacteria hence the above plant was selected for the present investigation. Ethanolic extract of Terminalia bellerica outer coat, fruit, and the seed was tested for antimicrobial activity against the isolated Multi Drug-Resistant Bacteria, and the MIC90 value was determined. Ethanolic extract of T. bellerica outer coat having the highest zone of inhibition was further fractionated, and four individual fractions, F1 (water), F2 (50% ethanol and water), F3 (ethanol), and F4 (acetone) were tested for antimicrobial activity against isolated Multi Drug-Resistant Bacteria. Staphylococcus saprophyticus, which was isolated from Hospital effluent and identified by 16 s-rRNA sequencing, was found to be...
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Posted by admin on Sep 30, 2021 in |
Natural phenolic acids alkyl esters viz methyl, ethyl, propyl was synthesized and characterized by spectral means FTIR, 1HNMR, and 13CNMR. All the synthesized esters were examined for their antimicrobial potential, preservative efficacy and antioxidant potential. Among the synthesized ester derivative caffeic acid and gallic acid, derivatives were displayed excellent antioxidant and antimicrobial potential. They were further evaluated their preservative efficacy according to USP 2004 protocol for preservative effectiveness testing. Caffeic acid propyl ester and gallic acid ethyl ester exhibited promising preservative potential better than existing preservative agents. From the study, we can conclude that these caffeic and gallic acid derivatives can be used as lead compounds to further explore their application as preservative agents in pharmaceuticals and in the food...
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