Posted by admin on Jul 1, 2012 in |
Vismia guianensis is a plant species of high occurrence in the Amazon and northeastern Brazil, which has been studied lately, because of its antimicrobial and anticancer properties.In order to make an herbal medicine, National Agency for Sanitary Surveillance of Brazil, recommends the production of a drug and plant extracts analysis report indicating: method, specifications and results obtained. The drug was characterized by particle size, amount of water and the total ash content; and plant extract through its density, pH and dry residue. The quantification of total anthraquinones and method validation was done by UV-VIS spectroscopy. The drug in this study produced a coarse powder whose determination of water is within the acceptable limits and the total ash content was 1.64%. The extractive solution showed a low pH, density of 0.89 mg/mL and 9.5% on yields from solids. HPLC found that the EtOAc fraction of the plant extract is consisted of phenolic compounds and anthraquinones. And the method of quantification of total anthraquinones, using emodin as external standard, was validated...
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Posted by admin on Jul 1, 2012 in |
There is a continuous and urgent need to discover new antimicrobial compounds with diverse chemical structures and novel mechanisms of action because there has been an alarming increase in the incidence of new and re-emerging infectious diseases. In recent years, drug resistance to human pathogenic bacteria has been commonly reported from all over the world. In the present scenario of emergence of multiple drug resistance to human pathogenic organisms, this has necessitated a search for new antimicrobial substances from other sources including plants. In the present study aqueous- ethanol extract of ten plants each belonging to different families was evaluated for antibacterial activity against medically important bacteria viz. S. aureus (MTCC 3160), B. subtilis (MTCC441), E. coli (MTCC40), K. pneumoniae (MTCC3384), P.mirabilis (MTCC425), P.aeruginosa (MTCC741). The in vitro anti-bacterial activity was performed by agar disc diffusion and agar well diffusion method. P. mirabilis was the most resistant bacterium while S. aureus was the most susceptible bacteria. Amongst the plant species studied, Terminalia chebula showed best antibacterial...
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Posted by admin on Jul 1, 2012 in |
The use of herbal drugs for the prevention and treatment of various health ailments has been in practice from time immemorial. Acacia arabica has been reported to be effective against a variety of disease including diabetes, skin disease and most concerning with cancer. The fresh plants parts of Acacia arabica is considered as astringent, demulcent, aphrodisiac, anthelmintic, antimicrobial, antidiarrhoeal, with good nutritional value in Indian traditional medicine system. This article briefly reviews the ethanobotanical as well as medicinal uses of Acacia arabica with plant description. This is an attempt to compile and document information on different aspect of Acacia arabica and its potential use. More studies are needed before the pharmacological properties of Acacia arabica can be utilized in...
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Posted by admin on Jul 1, 2012 in |
Chalcones are 1, 3-diphenyl-2-propene-1-one, consist of two aromatic rings linked by a three carbon α, β-unsaturated carbonyl system. The chemistry of chalcones has generated intensive scientific studies throughout the world. Especially interest has been focused on the synthesis and biodynamic activities of chalcones. These are considered to be precursors of flavonoids and isoflavonoids. The aim of this review is to summarize chalcones and their diverse pharmacological activities like anticancer, antimicrobial, analgesic and antiviral activities...
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Posted by admin on Jun 1, 2012 in |
Phytochemical screening and antibacterial activity of aqueous and methanolic root extracts of Stachytarpheta indica Vahl. was assessed. Phytochemical analysis revealed the presence of flavonoids, terpenoides, tannins and reducing sugars. The antibacterial properties of both the aqueous and methanolic extracts were studied against clinically important bacteria viz., Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa and Enterobacter aerogens by disc diffusion method. The aqueous extract showed significant activity against all the presently investigated species of bacteria which is comparable with standard antibiotic streptomycin. At the concentrations of 50-100µg /disc, aqueous extract showed significant zone of inhibition against E. coli, (14 mm), B. cereus (13 mm), P. aeruginosa, (17 mm), and E. aerogens (7 mm). Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) have been determined. The MIC values observed was 20, 30, 5 and 25µg/ml (for aqueous extract) and 40, 35, 20 and 30µg/ml (for methanolic extract) against E. coli, B. cereus, P. aeruginosa, and E. aerogens respectively. Further isolation of active compound responsible for the activity could be the potential...
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