Posted by admin on Apr 1, 2012 in |
The main objective of this review is to provide advance information for the drug discovery research from the divine herb Kalanchoe pinnata, which contains a wide range of active compounds, including alkaloids, triterpenes, glycosides, flavonoids, steroids, bufadienolides, lipids and organic acids. The pharmacological studies are reviewed and discussed, focussing on activities as immunomodulator, CNS depressant, analgesic, antimicrobial, anti-inflammatory, antiallergic, antianaphylactic, antileishmanial, antitumorous, antiulcerous, antibacterial, antifungal, antihistamine, antiviral, febrifuge, gastroprotective, immunosuppressive, insecticidal, muscle relaxant, sedative, anticancer. Now it becomes endangered plant which needs to be conserved as well as explored for its significant green...
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Posted by admin on Mar 1, 2012 in |
The present study was carried out to illustrate the relative evaluation of phytochemical constituents and antimicrobial activity of leaves of Eclipta alba and Aphanamixis polystachya and bark of Premna integrifolia in two different solvents. A preliminary phytochemical analysis was done and concluded that the presence of alkaloids, tannins, flavonoids and glycoside in both extracts of the above plants. The antimicrobial activity was tested using disc diffusion method against eight pathogenic bacteria using Kanamycin as antibiotic standards. The outcome showed that the antibacterial activity was effective in chloroform and ethyl acetate fractions of tested extracts. The MIC was determined in two different solvents of both extracts and observed that chloroform and ethyl acetate possess minimum inhibition in both extracts. From the current investigation, it can be concluded that Eclipta alba, Aphanamixis polystachya and Premna integrifolia crudeextracts have quite effective antimicrobial activity and potent phytochemical constituents....
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Posted by admin on Feb 1, 2012 in |
Crude ethanol and methanol extracts from dried and fresh leaves of Simarouba glauca were tested for their inhibitory activity against two food borne pathogenic microorganisms (Staphylococcus aeureus and Escherichia coli) and two food spoilage microorganism (Bacillus subtilis and Pseudomonas aeurogenosa). Screening for antimicrobial activity using well diffusion assay showed the inhibition against entire tested microorganisms. On the other hand the maximum zone of inhibition was recorded of fresh leaves methanol extract (FLM) about 11 mm against Escherichia coli and the lowest zone of inhibition was recorded of fresh leaves methanol extract (FLM) about 2 mm against Bacillus subtilis. Minimum inhibitory concentrations (MIC’s) of extracts were determined using agar dilution method on the same test microorganisms. Fresh leaves methanol (FLM) extract gave MIC value ranging from 160 to 10,240 parts per million (ppm). Result showed that the Bacillus subtilis was the most sensitive...
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Posted by admin on Jan 1, 2012 in |
Chromolaena odorata or siam weed is regarded as one of the most harmful weeds present on earth. Many efforts are being made for the control of this weed. But, none of them have provided any significant success. It has been utilized in the traditional medicinal systems for its curative properties for centuries. Some of the current studies have revealed its medicinal properties which have lead to an enhanced image of this plant as a medicinal herb. It showed anti-inflammatory, anti pyretic, analgesic, antimicrobial, cytotoxic and many other relevant medicinal properties in an appreciable...
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Posted by admin on Dec 1, 2011 in |
Neonatal sepsis is one of the commonest cause of neonatal mortality in the developing world which can be classified into early onset sepsis (EOS) which occurs in the first 7 days of life and late onset sepsis (LOS) which occurs ≥7 days of life. E. coli has been reported to be one of the significant and most common nosocomial pathogen which may cause septicemia, pneumonia and meningitis in the newborn. Most of the antibiotics which have been used extensively as life saving are rendered useless because of the emergence of resistant strains of bacterias. Therefore for determining the prevalence and antimicrobial susceptibility pattern of E. coli which is responsible for EOS and LOS and to establish the relationship with birth weight, a total of 229 blood samples were obtained from the neonates admitted to neonatal intensive care unit (NICU) who showed the clinical signs and symptoms of neonatal sepsis and sent for culture and sensitivity. Out of these 229, 102 showed the positive culture, among which early onset sepsis...
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