Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
FERULIC ACID: A NATURAL ESSENTIAL COMPOUND HAVING POTENTIAL INDUSTRIAL AND MEDICINAL PROPERTIES
The ubiquitous compound 4-Hydroxy-3-methoxy cinnamic acid, also known as ferulic acid, constitute. A bioactive ingredient of many food that may offer a potential therapeutic effects useful in the treatment of cancer, diabetes, lung and cardiovascular disease. It is also effective against the disorders relative to oxidative stress, including certain neurodegenerative diseases. Ferulic acid is widel...
1946
1364
COMPREHENSIVE REVIEW ON ORPHAN DRUG REGULATIONS IN THE USA, EU, JAPAN, AND AUSTRALIA: POSSIBLE RECOMMENDATIONS TO SPECIFIC CHALLENGES
Orphan drugs are medicinal products intended to diagnose, prevent, or treat life-threatening or debilitating rare diseases. In some parts of the world, a rare disease is also addressed as an orphan disease due to its poor diagnosis mechanism, low prevalence, and limited treatment options. The United States, Japan, Australia, and the European Union have adopted policies promoting orphan drugs devel...
2740
1617
FORMULATION AND EVALUATION OF SUSTAINED-RELEASE TABLET HAVING GENISTEIN
Genistein is phytoestrogens that function on estrogen receptors through a receptor-dependent mechanism. Genistein is commonly used to alleviate menopause symptoms, lower breast cancer risk, protect against prostate problems, improve bone health and lower the risk of heart disease. This research aims to create Genistein oral tablets with a long release time. In a rotary tableting machine, tablets w...
2126
1095
DEVELOPMENT OF NATEGLINIDE MODIFIED RELEASE DOSAGE FORM USING ELEMENTARY OSMOTIC PUMP (EOP) AND PUSH-PULL OSMOTIC PUMP (PPOP) METHODS
Objective: The aim of the study was to develop osmotic tablets of nateglinide by two methods, namely elementary osmotic pump (EOP) and push-pull osmotic pump (PPOP) method for controlled drug release. Methods: Initially, pre-compression parameters were studies for the tablet blend in both EOP and PPOP methods. The tablets were prepared by the wet granulation method in both methods. The prepared t...
1792
876
PATTERN OF ANTIDEPRESSANT PRESCRIPTION IN PATIENTS SUFFERING FROM DEPRESSIVE DISORDER IN A TERTIARY CARE HOSPITAL
Background: Depression is becoming an important health problem worldwide because of its relatively high lifetime prevalence, significant disability, suffering, dysfunction, and economic burden caused by it. Objectives: The present study was conducted with the objective to determine the prescribing pattern of antidepressant drugs in patients suffering from depression disorder in the psychiatric out...
1976
1131
FORMULATION AND EVALUATION OF CANDESARTAN CILEXETIL LOADED SOLID LIPID NANOPARTICLES WITH IMPROVED BIOAVAILABILITY
In this present work, BCS class II Candesartan celexitil, as an angiotensin receptor blocker used mainly for the treatment of high blood pressure and congestive heart failure, was successfully loaded in the solid lipid nanoparticles (SLNs) by using hot high-speed homogenization method. The SLN formulations were prepared and optimized by Box Benhken design study. The SLN was characterized by Nanoph...
1952
969
CORRELATION OF ANTIOXIDANT, ANTIBACTERIAL AND PHYTOCHEMICALS OF LEAVES AND ROOTS EXTRACTS OF CLERODENDRUM INFORTUNATUM
The leaves and roots extracts of Clerodendrum infortunatum was evaluated for its potential antioxidant and antibacterial properties. The correlation studies with phytochemicals were performed, which has not been widely reported yet. Clerodendrum infortunatum leaves and roots were screened for the presence of phytochemicals and were found positive for carbohydrates, saponins, alkaloids, tannins, ph...
1930
1222
DESIGN SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NOVEL BENZHYDRYL PIPERAZINE DERIVATIVES AS A NEW CLASS OF ANTI-CONVULSANT AGENTS
A novel series 3(a–d) 1-(4-benzhydryl piperazin-1-yl)-3-(di substituted) propan-1-one &1-(4-benzhydrylpiperazin-1-yl)-3-(piperidin-1-yl) propan-1-one (3e) & 1-(4-benzhydrylpiperazin-1-yl)-3-morpholinopropan-1-one (3f) compounds have been synthesized and screened for its anticonvulsant and neurotoxic activity, After i.p. injection to rat at doses of 30, 100, and 300 mg/kg body weight. Syn...
1888
1343
NANOTHERAPEUTIC APPROACHES, PHYTOCHEMISTRY AND PHARMACOLOGICAL PROSPECTS OF PLANT MUSSAENDA FRONDOSA LINN: A HOLISTIC INVESTIGATION
Medicinal plants provide numerous benefits to human health. Mussaenda frondosa Linn belongs to the Rubiaceae family, which has 500 genera and 5300 medicinal plant species. Mussaenda is a flowering plant genus with many beautiful species. Ayurveda, an ancient Indian healing system, describes many herbs, oils, and minerals. People have known about plants' medicinal value since prehistoric times. Mus...
2641
3202
ANTI-INFLAMMATORY EFFECT OF DISEASE-MODIFYING ANTI-RHEUMATIC DRUG, LEFLUNOMIDE: A REVIEW
The epidemiology, pathophysiology, clinical capabilities, diagnosis and scientific route of rheumatoid arthritis (RA) and the function of disorder-editing anti-rheumatic tablets (DMARDs) in its remedy are reviewed. RA, a giant disorder affecting humans of all races and sexes around the sector, has an unknown and perhaps multifactorial etiology. Conflicting proof supports RA's immune-complex, infec...
1691
1040