Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
LITHIUM CHLORIDE RESCUES RETINAL GANGLION CELLS IN RAT MODEL OF GLUTAMATE EXCITOTOXICITY
Retinal ganglion cell (RGC) death is distinctive of many ophthalmic disorders, such as glaucoma, optic neuropathies, and various retinovascular diseases. N-methyl-D-aspartate (NMDA)-type glutamate receptor (NMDAR)-mediated excitotoxicity is thought to be an important contributor to RGC death. Uninterrupted activation of a large number of NMDARs leads to increases in intracellular calcium loads, in...
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FORCED DEGRADATION STUDY OF DARUNAVIR ETHANOLATE AND RITONAVIR COMBINATION IN ACIDIC, BASIC AND OXIDATIVE CONDITIONS ESTABLISHING DEGRADATION PRODUCTS
A simple, precise, and rapid stability indicating RP-HPLC method has been developed for the simultaneous estimation of darunavir ethanolate and Ritonavir in Pharmaceutical dosage form in the presence of degradation products. It involved the Zorbax bonus, 150 mm × 4.6 mm of 3.5 μm particles packing stationary phase. The separation was achieved using mobile phase a consists of ammonium acetate buf...
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C-TERMINAL CLAW STABILISATION IN CORVUS AVIAN BETA DEFENSIN 7 AND ITS MUTATION STUDIES
Antimicrobial peptides are considered as promising and potential next-generation antibiotics on account of their broad spectrum of antimicrobial activity and unique mode of microbial killing. For therapeutic application, it is essential to consider the hemolytic or cytotoxic property of AMPs along with antimicrobial function. In the current study, an avian beta-defensin 7 (AvBD7) gene was identifi...
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ISOLATION AND CHARACTERIZATION OF SOME PHYTOCHEMICAL COMPOUNDS FROM THE METHANOLIC EXTRACT OF SOLANUM TORVUM SWARTZ FRUITS
Solanum torvum Sw. belonging to the family Solanaceae is locally called as pea eggplant, sundai and cherry egg-plant in India. The fruits of Solanum torvum Sw. used to cure diseases of the diuretic, malaria, stomach aches, problems with the spleen, treat coughs, improve the eyesight, treats headaches which attribute many properties in Ayurveda, siddha, unani and local health traditions. The purpos...
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GREEN SYNTHESIS OF SILVER NANOPARTICLES USING ROOT EXTRACT OF AERVA TOMENTOSA FORSK. AND ANALYSE ANTIBACTERIAL AND ANTIOXIDANT PROPERTY
During the present investigations attempt was made to the green synthesis of silver nanoparticles using root extract of Aerva tomentosa Forsk. and to analyze its antibacterial and antioxidant activities. Exposure of the root extract of Aerva tomentosa to aqueous AgNO3 resulted in the formation of silver nanoparticles. The synthesis of silver nanoparticles was confirmed by UV-Vis spectrophotometer ...
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SCREENING AND EVALUATION OF ANTIDIABETIC POTENCY OF VERNONIA ARBOREA USING ZEBRAFISH MODEL
Introduction: Vernonia arborea, belonging to the Asteraceae family, found in the Western Ghats of India and Sri Lanka, was traditionally used in wound healing. It is proven that some of the plants of this genus have anti-diabetic properties. e.g., V. amygdalina. So this study was done to screen and to evaluate the anti-diabetic potency of the leaf extract of Vernonia arborea in diabetic Zebrafish ...
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ANTIBACTERIAL ACTIVITY OF THREE URTICA SPECIES
The antimicrobial activity of Urtica dioica L. and Urtica urens L. has been reported; however, there are no reports regarding Urtica mexicana Liebm., which is widely distributed in central Mexico. U. urens and U. mexicana were collected in Amecameca and U. dioica was collected in Toluca Valley, both located in the state of Mexico. Crushed leaves of the plants were soaked consecutively in hexane, d...
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IN-SILICO DOCKING OF BIOACTIVE COMPOUNDS DERIVED FROM CASSIA AURICULATA FLOWER EXTRACT AGAINST NS2B-NS3 PROTEASE OF DENGUE VIRUS
Dengue is a fatal disease connected to the environment that spreads rapidly. As there is currently no effective vaccine against dengue and no exact treatment for the disease, controlling and preventing dengue fever outbreaks are essential steps for keeping people healthy. Dengue viruses are a member of the Flaviviridae family, mosquito-borne, and causative agents for dengue fever. Bioactive compou...
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FABRICATION OF CHITOSAN ALGINATE NANOPARTICLE BASED FIBRE OPTIC BIOSENSOR
In this work, a highly sensitive and selective nanoparticle-based fluorometric biosensor has been reported for the detection of asparagine levels. The L-asparaginase loaded chitosan alginate nanoparticles of size 396 nm with 600 µL of L-asparaginase (44.4 IU/mg) showing 83.5% entrapment efficiency was fabricated via ionic gelation method. In the presence of enzyme L-asparaginase (biocomponent) th...
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EFFECT OF CHROMIUM ON MORPHOLOGICAL AND BIOCHEMICAL RESPONSES ON AQUATIC MACROPHYTE PISTIA STRATIOTES L. (WATER LETTUCE)
The current work reports an ecofriendly approach to study morphological and biochemical responses of Pistia stratiotes L. (Water lettuce) were investigated. The assessment of morphological, biochemical parameters, and accumulation of chromium in free-floating macrophyte exposed at its various concentrations viz. 0.25, 0.50, 1.25, and 2.5 ppm of chromium at the regular intervals of 4, 8, and 12 day...
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