Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
TRANSCORNEAL PERMEATION OF OFLOXACIN BY AMINO ACID TRANSPORTERS
The research was carried out to formulate and evaluate ophthalmic solutions of Ofloxacin with amino acid transporters and compare the transcorneal permeation of Oflaxacin with that of the standard. In the study three different eye drop formulations were prepared by conjugation of the drug with different amino acids such as Alanine, Glycine and Leucine by solvent evaporation technique, the extent o...
4383
1823
EFFECT OF COMPACTION PROCESS IN GRANULOMETRY
Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The aim of the present study is to evaluate the effect of manufacturing process on critical quality attribute on In-process parameters (Granules). Quetiapine fumarate was selected as a model drug for sustained release drug delivery system manufactured ...
6913
2643
FORMULATION AND CHARACTERISATION OF SUSTAINED RELEASE CARVEDILOL TABLET FROM RESERVOIR PELLETS
Sustained release Carvedilol tablets constituting reservoir pellets developed in this study is an attempt to investigate the effect of drug release from matrix. The sustained release Carvedilol tablets were prepared by using different combination with release modifier (ethyl cellulose 10 cps and Eudragit RS 100). Tablets containing disintegrant pellets (Crosspovidon) with active ingredient demonst...
6526
2210
ROLE OF THE INCRETINS IN HYPOGLYCEMIC EFFECT OF PHLOGACANTHUS THYRSIFLORUS NEES IN CHEMICALLY INDUCED DIABETIC MICE
Objective: This study was aimed to evaluate the role of GLP-1, GIP in the hypoglycemic activity of Phlogacanthus thyrsiflorus Nees. Materials and Methods: We have evaluated the influence of Phlogacanthus thyrsiflorus Nees, a traditionally used antidiabetic medicinal plant on some metabolic parameters, glucose homeostasis, insulin production, glucagon like peptide 1 (GLP1) and gastric Inhibitory Po...
4000
1983
IDENTIFICATION OF AEROTOLERENCE GENE BATA AND BATB IN SUBGINGIVAL MICROFLORA: AGGREGATIBACTER ACTINOMYCETEMCOMITANS, TANNERELLA FORSYTHIA AND PREVOTELLA INTERMEDIA
Subgingival obligate anaerobes present within the biofilm such as Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia and Aggregati bacter actinomycetemcomitans have been implicated in the initiation and progression of periodontal disease. Recent documentation has demonstrated that P.gingivalis is capable of maintaining its viability when exposed to oxidative stress by expressing...
4189
1939
THE EFFECT OF DOXYCYCLINE HYDROCHLORIDE ON MMP-2 AND 9 IN EXPERIMENTALLY INDUCED PERIODONTITIS – AN ANIMAL STUDY
The periodontal tissues undergo constant changes of remodelling when subject to bacterial infection and the resultant host response. The balance between enzymes secreted by the host such as matrix metalloproteinases (MMPs) and their antagonists tissue inhibitor of metalloproteinases (TIMPs) are major contributors to the progression of periodontal destruction. A sub-type of MMPs referred to gelatin...
4162
1853
EFFECTS OF STREPTOZOTOCIN- INDUCED TYPE I DIABETES MELLITUS ON CATION CONTENTS IN URINARY BLADDER TISSUES OF THE RAT
Diabetes mellitus is known to induce microvascular changes and alterations to neuronal functions. Diabetic neuropathy and diabetic nephropathy are two of the major long-term complications of diabetic mellitus (DM). The main aim of the comparative study is to investigate the role of cations contents compared to the age matched control.Adult rats were humanely killed and detrusor muscles of urinary ...
3958
1629
TO INVESTIGATE THE EFFECTS OF GINGER-JUICE (ZINGIBER OFFICINALE ROSCOE) ON AMPHETAMINE-INDUCED LOCOMOTOR ACTIVITY IN RAT
To investigate the effects of ginger-juice (Zingiber officinale roscoe) on amphetamine-induced locomotor activity in rat. Methods: (A) Albino rats (n=6-12) were administered G.J at the single doses (4 ml/rat, p.o) as single administration (acute) and chronic treatment over period of 7 days. Following this assessment was done. Effect of treatment with G.J acutely and chronically (7days) administere...
4176
2110
THE CLINICOPATHOLOGICAL PROFILE IN PATIENTS WITH EPITHELIAL OVARIAN CARCINOMA
The malignant tumors of ovary are a group of disease with varying clinical and biological behavior. It is fifth leading cause of death from cancer in women and the leading cause of death from gynecological cancer. This retrospective study has been undertaken to analyze patients of epithelial ovarian cancers. These cases were analyzed for various features like age, stage at presentation, histologic...
4447
1611
COMPARATIVE ANALYSIS OF DRUG-INDUCED PARKINSONISM LIKE BEHAVIORS IN C57BL6 BLACK MICE USING A FORCE PLATE ACTIMETER.
This study aims to compare the Parkinsonism behavior induced by two drugs: Tacrine (9-amino-1,2,3,4-tetrahydroaminoacridine hydrochloride hydrate and MPTP (1-methyl, 4-phenyl 1,2,3,6 tetrahydropyrolidine) using a Force Plate Actimeter (FPA). 25 C57BL/6 black mice were equally divided into two groups for 5mg/kg tacrine and 30mg/kg MPTP experiment. Both groups contained sham, 5mg/kg tacrine or 30mg/...
4307
2249