Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
IN-SILICO DESIGN AND DOCKING STUDY OF SOME 4-(10-ACETYL-10H-PHENO-THIAZINES-3-YL)-1-PHENYLAZETIDIN-2-ONE DERIVATIVES
Background: The current study used computational approaches to investigate the molecular, physicochemical and drug-like properties of some 4-(10-acetyl-10H-phenothiazines-3-yl)-1-phenylazetidin-2-one derivatives. Methods: The structures of the compounds were drawn using Chemdraw ultra12 and smiles were generated using ACD chem sketch software. The physicochemical and molecular properties were calc...
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NOVEL FORMULATION AND ANALYTICAL EVALUATION OF BI-LAYERED TABLETS OF ENALAPRIL MALEATE, HYDROCHLOROTHIAZIDE AND NIFEDIPINE
The present research is intended for the formulation development, optimization, and in-vitro evaluation of bi-layer tablets containing Enalapril maleate, hydrochlorothiazide in the immediate release layer and Nifedipine in the sustained release layer based on GEMINEX technology. The impact of formulation variables such as combination of polymers and coating solution on the drug release was evaluat...
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GREEN SYNTHESIS OF SILVER NANOPARTICLES (AGNPS) USING MANILKARA ZAPOTA FRUIT EXTRACT: POTENTIAL ROLE IN CATALYTIC DEGRADATION OF METHYLENE BLUE DYE
Present study reported a simple, rapid, eco-friendly and economical method for efficient production of AgNPs utilizing Manilkara zapota (M. zapota) extract. UV-Vis spectroscopic analysis was employedto ascertain the formation and stability of the synthesized AgNPs. The AgNPs were further characterized using TEM (Transmission Electron Microscopy), DLS, FT-IR, and XRD. The AgNPs exhibited a clear SP...
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ANALGESIC ACTIVITY OF ETHANOLIC, HEXANE AND CHLOROFORM EXTRACTS OF SESAME SEED BY THERMAL HEAT METHOD IN ALBINO MICE
Background: Pain is a common symptom having huge public health importance. Conventional analgesics relieve pain effectively but cause various unwanted side effects. Hence the search for a novel analgesic with favourable risk-benefit profile is essential. Objectives: The current study was undertaken to investigate the analgesic activity of the ethanolic, hexane and chloroform extracts of sesame see...
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EXPLORING THE DIVERSITY OF ENTEROPATHOGENS IN NEONATES
Diarrhea alters the movement of ions and water that follows an osmotic gradient and leads to Loose, watery stools, abdominal cramps, abdominal pain, fever, bloating, blood, and mucus in the stool. Numerous critical cases have been observed in both infants and adults. The main objective of this study is based on an exploration of risk factors of diarrheal infection caused in neonates by entering pa...
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USING AN IMMUNOINFORMATIC APPROACH, IDENTIFICATION OF B-CELL ENVELOPE PROTEOME FOR MULTIPATHOGENIC DENGUE AND ZIKA VIRUSES
Mosquitoes are carriers of the DENV and ZIKV diseases. DENV and ZIKV are epitopes. The current performance and technique of some of the most frequently used B-cell epitope predictors used for DV and ZV proteomes are reviewed in this paper. Our specific prediction methods, ABC pred, BC pred, and AAP Methods, as well as FBC pred, were utilized to predict 1529 B cell epitopes. For the B cell epitops,...
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COMPARISON AND EVALUATION OF DISPENSING ERRORS FROM 2017 TO 2018 AT KING ABDULAZIZ MEDICAL CITY (KAMC) AND KING ABDULLAH SPECIALIZED CHILDREN’S HOSPITAL (KASCH), RIYADH, THROUGH THE SAFETY REPORTING SYSTEM (SRS)
Any errors in medical dispensing may threaten the patient's life. Hence, this research aimed to compare and evaluate the dispensing errors and to identify its prevalence and severity through the safety reporting system (SRS) and providing feedback at “King Abdulaziz Medical City, Central Region (KAMC-CR)” and “King Abdullah Specialized Children’s Hospital (KASCH)”.The KAMC-SRS was used t...
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CONTROLLED DELIVERY OF METFORMIN: FORMULATION DEVELOPMENT AND IN-VITRO CHARACTERIZATION OF MATRIX TABLETS USING NATURAL AND SYNTHETIC POLYMERS
Diabetes Mellitus is a chronic metabolic disorder that has become increasingly evident, necessitating more stable and continuous therapeutic monitoring. Metformin Hydrochloride, being the primary treatment choice in type II Diabetes, presents certain limitations like improper GI absorption and the need for multiple dosing. Controlled drug delivery proves to be a better option in such conditions to...
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EVALUATION OF RATIONAL DRUG USE AND EFFICACY OF VARIOUS COMBINATIONS OF ANTIHYPERTENSIVE DRUGS COMMONLY PRESCRIBED FOR THE MANAGEMENT OF HYPERTENSION IN CKD PATIENTS AT TERTIARY CARE HOSPITAL
To evaluate the rational drug use and efficacy evaluation of various combinations of Antihypertensive drugs commonly prescribed for the management of hypertension in CKD patients at tertiary care hospitals. This is an observational and comparative study. A randomized trial was carried out in 300 patients after obtaining the consent for 1 year in a tertiary care hospital in Mahabubnagar. The data c...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF NEWER COUMARIN DERIVATIVES AS ANTIMICROBIAL AGENTS
For the synthesis of a series of novel Coumarin derivatives, an efficient and easy approach has been designed. 1H-NMR and Fourier Transformed Infrared (FTIR) characterize the structures of freshly synthesized compounds, which are then evaluated for antibacterial activity in vitro by calculating the zone of inhibition and minimum inhibitory concentration. The antibacterial and antifungal activity o...
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