Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
VITAMIN C, THIAMINE AND HYDROCORTISONE IN SEPTIC SHOCK: A RETROSPECTIVE ANALYSIS
Background: Sepsis leads to approximately 11 million deaths annually. Objectives: We studied the effectiveness of using a combination of intravenous hydrocortisone (50mg QID), Ascorbic Acid (1.5g QID), and Thiamine (200mg BD) (HAT) to reduce mortality among septic patients compared to a historical control group. Materials and Methods: This retrospective, observational study was conducted between J...
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EVALUATION OF SEEDS OF AN INDIAN SACRED PLANT AEGLE MARMELOS, FOR THEIR ANTIOXIDANT AND CYTOTOXIC POTENTIAL
Introduction: The seeds of Aegle marmelos (bael) are less explored for their therapeutic activity; cytotoxic activity of bael seeds was yet to be studied. The present study aims at finding the cytotoxic activity of the successive extracts and the flavonoid fraction from the methanolic extract of the seeds. Methods: The extracts were prepared using solvents (petroleum ether, chloroform, ethyl aceta...
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ANTIBIOTICS SENSITIVITY PATTERN OF E. COLI SPECIES ISOLATED AT TERTIARY CARE HOSPITAL
Worldwide antimicrobial resistance is a serious problem and differs from region to region. This study has designed the determination of the incidence and sensitivity pattern of Escherichia coli (E. coli) and discusses the general issues related to antimicrobial resistance. Prospective study was carried out between JAN to April 2020. Samples of urine, blood, pus and miscellaneous (fluids, swabs and...
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ROBUST SIMPLE ANALYTICAL TECHNIQUE FOR DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR ESTIMATION OF TENELIGLIPTIN IN PHARMACEUTICAL DOSAGE FORM
As per the ICH guidelines and regulatory authorities' worldwide, it has become mandatory to establish a stability-indicating assay method (SIAM) for the drug substance (DS) and drug product (DP) to generate the stability data. It was undertaken to develop a precise, accurate, reliable, rapid, simple and specific method for estimating Teneligliptin free of interference from its probable degradation...
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EVALUATION OF ANTI-ALZHEIMER ACTIVITY OF ETHANOLIC EXTRACT OF ORIGANUM VULGARE LEAVES IN WISTAR ALBINO RATS
Alzheimer's disease, the most frequent cause of dementia, is a major global health concern with enormous societal and individual ramifications. Some of the hallmarks linked with AD include a decrease in acetylcholine (ACh) levels in the synapse, the buildup of extracellular beta-amyloid plaques, and tau protein intraneuronal tangles. Low levels of ACh have been linked to memory and reasoning probl...
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STUDY OF SPECIFICITY, SENSITIVITY, EFFICIENCY & CLINICAL CORRELATION BETWEEN TIMP-1 AND MIF PROTEIN AS BIOCHEMICAL MARKERS IN COLORECTAL CANCER PATIENTS
Background: Colorectal cancer is the fifth most common cancer and the leading cause of cancer-related deaths in India. The incidence, mortality, and prevalence rates are consistently higher. Precautionary measures in preventing colorectal cancer still remain a challenging issue. Aims and Objectives: This study was undertaken to correlate the specificity, sensitivity & efficiency of TIMP-1 and ...
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CARDIOPROTECTIVE EFFECT OF SANDAL WOOD (SANTALUM ALBUM LINN.): AN EXPERIMENTAL TRAIL
Background: In the Unani System of Medicine, Sandal safed (Sandalwood) is used in many cardiac problems as it possesses Mufarreh (exhilarant) and Muqawwi Qalb (cardiotonic) activities. The present study was designed to evaluate the cardioprotective effect of Sandal safed in Isoproterenol-induced Myocardial Infarction. Methods: Male Wistar rats, weighing 150-200gm, divided into five groups of ten i...
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DESIGN AND MOLECULAR DOCKING STUDIES OF N1-CHLOROACETYL-7-SUBSTITUTED- 4-METHYL-1, 5-BENZODIAZEPINE-2-ONE DERIVATIVES
Molecular Docking is an effective and competent tool for in-silico screening. It is playing an important and ever-increasing role in rational drug design. The main application lies in this structure-based virtual screening is the identification of new active compounds towards a particular target protein. In present investigation, few N1-chloroacetyl-7-substituted- 4-methyl-1, 5-benzodiazepine-2-on...
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COMPARATIVE EVALUATION OF ANALGESIC ACTIVITY OF SSRI (FLUOXETINE) AND SNRI (DULOXETINE AND VENLAFAXINE) IN EXPERIMENTALLY INDUCED CHRONIC NEUROPATHIC PAIN MODEL
Objectives: To investigate and compare the analgesic effect of fluoxetine (FLU), duloxetine (DUL) and venlafaxine (VEN) in animal models of chronic pain. Methods: Chronic pain was induced in albino rats using spared nerve injury and vincristine. Rats were divided into Control group/ Normal Saline (NS5), DUL group, FLU group, and VEN group. In spared nerve injury, sural branch of sciatic nerve was ...
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ANTI-DIABETIC ACTIVITY OF THE METHANOLIC EXTRACT OF SEEDS OF SYZYGIUM CUMINI IN STZ-INDUCED TYPE I DIABETES IN RATS
Background: Syzygium cumini (SC) usually acknowledged as Jamun. All components of the Jamun may keep used medicinally because of a wide range of diseases like cough, diabetes, dysentery and inflammation. Objectives: Present investigational on the anti-diabetic activity of the methanolic extract seeds of SC in STZ-induced Type I Diabetes in rats. Methods: Extracted SC was to be evaluated the toxici...
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