Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
ATTENUATION OF NEPHROTOXICITY INDUCED WITH CISPLATIN IN HEK 293 CELL LINES BY SAGADEVI NEI
Sagadevi nei is a Siddha polyherbal formulation indicated for Neerkattu and Neersurukku. The main ingredient of the formulation is Vernonia cinerea, belonging to the family Fabaceae, which has been proven scientifically to exhibit renal tubular regrowth. Based on Literature, each ingredient of the mixture has nephroprotective, diuretic, antioxidant, and anti-inflammatory properties. Cisplatin is a...
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IN-VIVO ANTI-ARTHRITIC EFFECT OF COMPARATIVE STUDY OF POLYHERBAL FORMULATIONS (MUNIPAYN, RUMALAYA FORTE) IN FCA INDUCED ARTHRITIC RATS
Rheumatoid arthritis (RA) is one of the most prevalent chronic inflammatory joint diseases which affect approximately 1% adult population in the worldwide. Polyherbal ayurvedic formulations (Munipayn and Rumalaya forte) reported to be effective as anti-inflammatory and anti arthritic activity. In-vitro anti-inflammatory of individual formulations (Munipayn and Rumalaya forte) were evaluated by alb...
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REVEALING SILYMARIN: HPTLC METHOD DEVELOPMENT AND VALIDATION
Silymarin, an intricate blend of flavonolignans obtained from Silybum marianum, or milk thistle, has drawn a lot of interest because of its possible medical uses. This study reports on the development and validation of an analytical technique that employs high performance thin layer chromatography (HPTLC) to estimate silymarin in pharmaceutical dosage forms (tablet) and bulk drug. Chloroform: meth...
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SYNERGISTIC CONVERGENCE: EXPLORING COMBINATIONS OF DIVERSE PHYSIOLOGICAL ACTIVITIES – A REVIEW
The development of effective therapeutic strategies for various remedial conditions often involves the exploration of synergistic interaction between two pharmacophores. The most frequent methods for multidrug therapy combining two or more active ingredients into a single, and creating hybrid molecular entities that can modulate numerous targets interaction gives a synergistic effect. As a result,...
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MEROPENEM INDUCED THROMBOCYTOSIS – A RARE ADVERSE DRUG REACTION
Thrombocytosis is defined as platelet count greater than 400, 000/mm3. Thrombocytosis can be either primary or secondary. Meropenem is a parenteral carbapenem antibiotic that has great bactericidal activity against almost all significant aerobes and anaerobes. Common adverse effects such as pain at the injection site, skin rash, transitory metabolic disorders such as increased liver enzyme ...
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STRENGTHENING IMMUNIZATION SYSTEMS THROUGH EFFECTIVE SUPPLY CHAINS: INSIGHTS FROM GLOBAL EFFECTIVE VACCINE MANAGEMENT INITIATIVE
The Expanded Programme on Immunization (EPI), launched in 1974, is the world’s major vaccination program against vaccine preventable diseases. Despite progress, the program’s success, measured through coverage rates, has recently stalled, especially in low-income countries where access to vaccines remains challenging. EPI’s effectiveness relies heavily on the Immunization Supply Chain, but t...
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IMPORTANT HUMAN GENES: THEIR LENGTH, LOCATION, PRODUCT, IMPORTANCE IN PROPER BODY FUNCTIONING AND INVOLVEMENT IN GENETIC DISORDERS
There are up to 25000 genes encoded by our genome however among them only some are being expressed on mass level. Some of these important genes are; ABO genes located at chromosome number 9, ALB genes located at chromosome number 4, BCL-2 genes located at chromosome number 18, CCR-5 genes located at chromosome number 3, CD4 genes located at chromosome number 12, CD8 genes located at chromosome num...
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BIOFILM INFECTIONS: A NEW THERAPEUTIC CHALLENGE
Biofilms are multicellular communities of bacteria. The ability to form biofilm is a universal attribute of bacteria and as bacteria can form biofilm in medical, industrial and environmental settings, it impacts human lives in many different ways. Bacteria undergo profound physiologic, morphologic and genetic changes as the transit from planktonic (free swimming, non-biofilm) form to surface attac...
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PATHOPHYSIOLOGY OF NEUROPATHIC PAIN: A SYSTEMIC REVIEW
Neuropathic pain is considered as an inappropriate response caused by a lesion or dysfunction in the PNS or CNS). Neuropathic pain can manifest itself as either without a stimulus (stimulus-independent pain) and/ or as pain hypersensitivity elicited after a stimulus (stimulus-evoked pain). Stimulus-independent pain includes symptoms described by the patient such as (a) continuous, burning pain (b)...
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RECENT TRENDS IN TREATMENT AND MANAGEMENT OF FILARIASIS
Filariasis is the name for a group of tropical diseases caused by various thread-like parasitic round worms (nematodes) and their larvae. The larvae transmit the disease to humans through a mosquito bite. Filariasis is characterized by fever, chills, headache, and skin lesions in the early stages and, if untreated, can progress to include gross enlargement of the limbs and genitalia in a condi...
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