Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
TEMPLATE SYNTHESIS AND SPECTRAL STUDIES OF BIOLOGICALLY ACTIVE NI(II), AND CU(II) TRANSITION METAL COMPLEXES OF TETRADENTATE AZA-OXO (N2O2) MACROCYCLIC LIGAND
A novel series of transition metal complexes of [M(C19H18N2O2S)X2], where M = Ni(II), Cu(II), X = Cl-, NO3-, ½ SO42- and (C19H18N2O2S) moiety corresponds to the tetradentate aza-oxo macrocyclic species, were synthesized by template condensation reaction of 1,4-bis(2-formylphenoxy)butane and thiourea in the presence of divalent metal salts in 1:1:1 ratio. The metal complexes were characterized and...
3354
1922
ASSESSMENT OF ANXIOLYTIC POTENTIAL OF SPIRULINA PLATENSIS
Spirulina platensis, planktonic blue-green algae, has been used as a source of protein (60-70%) and vitamin supplement for more than 15 years without any unknown adverse events. Traditionally, Spirulina platensis has been used as an antioxidant agent. However, no pharmacological work has been done to evaluate the anti-anxiety activity. The present study was premeditated for the evaluation of the ...
4665
1856
ANTIDIABETIC ACTIVITY AND POTENTIAL MECHANISM OF MUKIA MADERASPATANA LINN. IN RATS INDUCED BY HIGH FAT DIET AND LOW DOSE STZ
To evaluate the anti-diabetic effects of the Mukia maderaspatana Linn. (MML), and to explore the possible mechanism. High-fat diet and STZ (35 mg/kg) induced diabetic rats were administered with MML at two dose levels (200 and 400 mg/kg/day, p.o.) for 21 days. Fasting blood glucose, lipid and lipoprotein levels such as triglyceride (TG), total cholesterol (TC), high-density lipoprotein-cholesterol...
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FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF AMBROXOL HYDROCHLORIDE USING NATURAL POLYMER
Ambroxol hydrochloride is a potent mucolytic agent capable of inducing bronchial secretions used in the treatment of respiratory disorders. The Sustained release matrix tablets containing 75 mg Ambroxol hydrochloride were developed using different drug: polymer ratios. Sustained release matrix tablets were prepared by wet granulation method. Granules were prepared and evaluated for loose bulk dens...
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2936
ANTIFUNGAL GLYCEROGELATIN: ATTEMPT AT FORMULATION AND EVALUATION OF A POTENTIAL TRANSUNGUAL DRUG DELIVERY SYSTEM
Onychomycosis representing about 30% of mycotic cutaneous infections is the fungal infection that affects the nails. Although not life-threatening, it adversely affects the psychology of the patient whose nails become yellow, discolored, brittle, and unsightly. It may also pose serious problems in immunocompromised individuals. The current market of products for the treatment of onychomycosis incl...
7226
2310
A SURVEY ON LINE OF MANAGEMENT OF HYPERTENSION BY PRIMARY HEALTH CARE PHYSICIANS IN PUDUDCHERRY
Hypertension is one of the most important public health problems globally. If the blood pressure is effectively controlled, many of the disastrous complications of hypertension such as myocardial infarction, stroke, kidney failure, heart failure, and death can be prevented or delayed. Patients usually attend the family physicians first for any illness they are suffering, including hypertension. He...
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1329
METAPHORICAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP (2D & 3D-QSAR) ANALYSIS OF TYLOPHORINE DERIVATIVES AS EFFICACIOUS IN ANTIMALARIAL DRUG DESIGN
Quantitative Structure-Activity Relationship (QSAR) for tylophorine derivatives acting as Plasmodium kinases inhibitors has been developed. The proposed 2D-QSAR model was found to be statistically significant concerning training, cross-validation, and external validation. The contribution of carbon chains with aromatic and electronegative features are found to be the most important descriptors in ...
4033
1531
CORRELATION BETWEEN URINARY MICROALBUMIN, GLYCOSYLATED HAEMOGLOBIN AND SERUM MAGNESIUM IN TYPE 2 DIABETIC PATIENTS
Background and Objectives: Diabetes mellitus comprises a group of common metabolic disorders that share the phenotype of hyperglycemia. One of the leading causes of diabetes mellitus related morbidity and mortality is diabetic nephropathy. The earliest stage of diabetic nephropathy is Microalbuminuria, which is the excretion of extremely small quantities of albumin in the range of 30 - 300 mg/day....
3909
1820
QSAR STUDIES ON PPARγ AGONIST 2- ALKOXYDIHYDROCINNAMATES WHICH USE AS LEAD MOLECULE FOR THE SYNTHESIS OF NEW COMPOUNDS TO TREAT DIABETES AND NEUROLOGICAL DISORDER
Quantitative Structure-Activity Relationships (QSAR) is based on the assumption that the activity of a certain chemical compound is related to its structure. More precisely, this approach says that the activity or the property is related to the chemical structure through a certain mathematical algorithm or rule. Quantitative structure-activity relationship (QSAR) analysis used to understand the st...
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1401
EXPERIMENTAL EVALUATION OF TIGECYCLINE AND TEIKOPLANIN IN THE TREATMENT OF IMPLANT RELATED METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) OSTEOMYELITIS
Treatment of implant-related MRSA osteomyelitis is a real challenge both for the physician and the patient. We evaluated the comparative efficacy of tigecycline, a novel broad-spectrum glycycline antibiotic and the glycopeptide antibiotic teicoplanin in the treatment of implant-related MRSA osteomyelitis in an experimental rat model. Implant related MRSA osteomyelitis was studied in the tibial met...
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