Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
BACOPAMONNIERA, A NOOTROPIC HERB ALLEVIATES ABNORMAL MOLECULAR AND IMMUNOHISTOCHEMICAL CHANGES EVOKED BY CHRONIC EXPOSURE OF METHYLMERCURY IN RAT CEREBELLUM
Methylmercury (MeHg), a highly toxic environmental pollutant, induces oxidative stress and dysfunction in many cell types. Bacopa monniera is a perennial herb, and is used as a nerve tonic in ayurveda, a traditional medicinal system in India. This study was aimed to evaluate the effect of Bacopa monniera extract (BME) on MeHg-induced toxicity in rat cerebellum. Male Wistar rats were administered w...
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VASORELAXATION EFFECT PROMOTED BY THE CALCIUM CHANNEL BLOCKER VERAPAMIL COORDINATED TO RUTHENIUM (II): CHEMICAL AND BIOLOGICAL PROPERTIES
This paper presents the synthesis and physical-chemical characterization of a new terpyridine (tpy) ruthenium complex coordinated to the L-type calcium blocker channels verapamil (vera) obtained from commercial pill. Elemental analysis (%C N H), infrared (IR) and ultraviolet-visible (UV-vis.) spectroscopy, mass spectrometry (MS), and 13CNMR (nuclear magnetic resonance), and HPLC (high performance ...
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MEMBRANE SENSORS FOR THE SELECTIVE DETERMINATION OF TOLTERODINE TARTRATE IN PRESENCE OF ITS DEGRADATION PRODUCT
The construction and electrochemical response characteristics of polyvinyl chloride (PVC) membrane sensors for determination of Tolterodine tartrate (TT) in presence of its oxidative degradation product are described. The sensors are based on the ion association complexes of TT cation with sodium tetraphenyl borate (TT-TPB) [sensor 1] or phosphomolybidic acid (TT-PMA) [sensor 2] counter anions as ...
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EFFECT OF PROCESSING ON AMINO ACIDS CONTENTS OF FOUR SPECIES OF THE FAMILY CUCURBITACEAE
This study was carried out to evaluate the effect of boiling on amino acids contents of the fruits of four species of the family Cucurbitaceae which were Cucurbita maxima D, Cucurbita pepo L, Cucurbita moschata and Lagenaria siceraria variety supreme court. In this study, fresh fruit of the four species were subjected to conventional processing technique which is boiling as well as drying. The dry...
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QUANTIFICATION OF A CRUDE EXTRACT FROM HEDERA COLCHICA
Crude extract from the leaves of Hedera colchica (C. Koch) C. Koch proved to have an antiulcer activity in pharmacological experiences. Hederacolchisid F (HCF) is being the chemical marker of this plant, a simple and reliable HPLC method is developed for the quantitative evaluation of the extract using this compound. The chromatographic separation was achieved using an Eclipse XDB-Phenyl c...
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EFFECT OF ETANERCEPT AGAINST MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN MALE MICE
Objective: This study was undertaken to investigate the potential role of etanercept in amelioration of myocardial I/R injury induced by ligation of coronary artery in a mice model. Materials & methods: Adult male Swiss Albino mice were randomized into 4 equal groups. Group (1) sham group: mice underwent the same anesthetic and surgical procedure as the control group except ligation of LAD cor...
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COMPARATIVE ANALYSIS OF MOLECULAR INTERACTIONS BETWEEN DRUGS OF AQUEOUS PROPYLENE GLYCOL WITH CERTAIN ALCOHOLS AT 308.15K: AN INSIGHT FROM DENSITY AND VISCOSITY STUDIES
Density, ρ and viscosity, η of drug of aqueous solution of propylene glycol (PG) (3 m and 7 m) with tert-butanol/2-propanol have been measured over the entire composition range of alkanols at 308.15 K. From this experimental data, excess molar volume, , deviation in viscosity, Δη, and excess Gibbs free energy of activation of viscous flow, ΔG*E have been determined. Positive values of Δη, ...
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EMBLICA OFFICINALIS ENHANCES CARDIAC TISSUE REGENERATION IN TADPOLES OF THE FROG RANA CYANOPHLYCTIS (SCHNEIDER)
Emblica officinalis and its derivative (Ascorbic acid) have profound effect on development and regeneration and are widely used in the Indian System of medicine for the treatment of different type of disease. Here, we discussed the comprehensive account of the effect of aqueous extract of the fruit of E.officinalis with special reference to cardiac tissue regeneration in frog tadpoles. E.officinal...
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SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF 2-SUBSTITUTED BENZOTHIAZOLE DITHIOMIDOCARBONATE DERIVATIVES
A series of novel 2- substituted benzothiazole dithiomidocarbonate derivatives were synthesized by the reaction of 2-amino benzothiazole with various halides. The test compounds were screened for their antimicrobial activity (antibacterial and antifungal) by disc diffusion method and the results of the microbial activity indicates that the test compounds exhibited varying degree of antimicrobial a...
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FORMULATION DEVELOPMENT AND EVALUATION OF FENOFIBRATE AND ROSUVASTATIN IN COMBINATION TABLETS AND RELEASE RATE IMPROVEMENT
The work was aimed to develop an immediate release tablet formulation of Fenofibrate and Rosuvastatin in combination for better treatment as well as management of hypercholesterolemia and prevention of cardiovascular diseases. The target was also set to improve the dissolution profile of poorly soluble Fenofibrate. For manufacturing these immediate release combined formulation tablets, Hot-Melt Te...
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