Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
EFFECT OF COMPACTION PROCESS IN GRANULOMETRY
Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The aim of the present study is to evaluate the effect of manufacturing process on critical quality attribute on In-process parameters (Granules). Quetiapine fumarate was selected as a model drug for sustained release drug delivery system manufactured ...
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FORMULATION AND CHARACTERISATION OF SUSTAINED RELEASE CARVEDILOL TABLET FROM RESERVOIR PELLETS
Sustained release Carvedilol tablets constituting reservoir pellets developed in this study is an attempt to investigate the effect of drug release from matrix. The sustained release Carvedilol tablets were prepared by using different combination with release modifier (ethyl cellulose 10 cps and Eudragit RS 100). Tablets containing disintegrant pellets (Crosspovidon) with active ingredient demonst...
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A NEW SINGLE STABILITY INDICATING RP-ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY (RP-UPLC) METHOD FOR EVALUATION OF ASSAY OF BICALUTAMIDE FROM DOSAGE FORM AND SUITABILITY OF METHOD FOR DETERMINATION OF DISSOLUTION RATE AND RESIDUE ANALYSIS.
A new single stability-indicating isocratic reversed phase ultra-performance liquid chromatographic (RP-UPLC) method with a shortest run time of 2.5 minutes is developed for the determination of assay of bicalutamide an anti-cancer drug from its finished dosage form in the presence of its forced degradation products. The method is developed using Waters Aquity BEH C18 column with mobile phase cont...
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1321
ROLE OF THE INCRETINS IN HYPOGLYCEMIC EFFECT OF PHLOGACANTHUS THYRSIFLORUS NEES IN CHEMICALLY INDUCED DIABETIC MICE
Objective: This study was aimed to evaluate the role of GLP-1, GIP in the hypoglycemic activity of Phlogacanthus thyrsiflorus Nees. Materials and Methods: We have evaluated the influence of Phlogacanthus thyrsiflorus Nees, a traditionally used antidiabetic medicinal plant on some metabolic parameters, glucose homeostasis, insulin production, glucagon like peptide 1 (GLP1) and gastric Inhibitory Po...
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SYNTHESIS AND CHARACTERIZATION OF [16]- MEMBERED DIOXA DIAZA NAPTHALDEHYDE BASED MACROCYCLIC LIGAND AND ITS COMPLEXES OF Co(III), Ni(II) AND Cu(II) PERCHLORATE IONS
An hitherto new unreported [16]-membered dioxadiazanapthaldehyde based macrocyclic ligand (L) 2,11-dioxa-23,30-diaza heptacyclo [30.4.0.04,9.012,21.014,19.024,29.034,39] -tetraconta-12,14,16, 18,20,22, 24,26,28,30,32,34,36,38,40-pentadecaene, has been synthesized by two different synthetic routes each involving two stages. 2-Hydroxy-1-Napthaldehyde in the presence of potassium carbonate was trea...
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EFFICACY OF SODIUM HYPOCHLORITE IN CONTROLLING BACTERIAL INFECTIONS IN FIFTH INSTAR LARVAE OF ANTHEREAE MYLITTA DRURY (DABA TV)
Bacterial diseases are highly virulent and cause significant crop loss in Anthereae mylittadrury (Daba TV).Therefore an attempt has been made to evaluate the efficient concentration of sodium hypochlorite in controlling bacterial infection through studies on mortality, Total haemocytes, Protein carbonyl content, Alanine transaminase, Aspartate transaminase in the fifth in star larvae. Results reve...
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ALTERATIONS IN PLASMA ANTIOXIDANT ENZYME LEVELS AND SERUM LIPID PROFILE PARAMETERS IN RELATION TO LIPID PEROXIDATION IN INDIVIDUALS WITH MATERNALLY INHERITED TYPE 2 DIABETES MELLITUS
Aim: The present study aimed to evaluate the antioxidant potential and lipid profile parameters, in relation to lipid peroxidation in patients with maternally inherited type 2 diabetes mellitus and in healthy normal individuals. Methods: All standard methods were used to estimate enzymatic antioxidants [Catalase, Copper containing Superoxide Dismutase (CuSOD), Manganese containing Superoxide Dismu...
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THE EFFECT OF DOXYCYCLINE HYDROCHLORIDE ON MMP-2 AND 9 IN EXPERIMENTALLY INDUCED PERIODONTITIS – AN ANIMAL STUDY
The periodontal tissues undergo constant changes of remodelling when subject to bacterial infection and the resultant host response. The balance between enzymes secreted by the host such as matrix metalloproteinases (MMPs) and their antagonists tissue inhibitor of metalloproteinases (TIMPs) are major contributors to the progression of periodontal destruction. A sub-type of MMPs referred to gelatin...
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EFFECTS OF STREPTOZOTOCIN- INDUCED TYPE I DIABETES MELLITUS ON CATION CONTENTS IN URINARY BLADDER TISSUES OF THE RAT
Diabetes mellitus is known to induce microvascular changes and alterations to neuronal functions. Diabetic neuropathy and diabetic nephropathy are two of the major long-term complications of diabetic mellitus (DM). The main aim of the comparative study is to investigate the role of cations contents compared to the age matched control.Adult rats were humanely killed and detrusor muscles of urinary ...
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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTIFICATION OF BETULINIC ACID IN VITEX NEGUNDO L. AND ITS POLYHERBAL FORMULATIONS
The Vitex negundo, which is traditional Indian medicine, has been used for treatment of various diseases. A simple, sensitive, precise and accurate RP-HPLC method has been developed for the analysis of Vitex negundo L. samples and its polyherbal formulations for their Betulinic acid content. The extraction was checked using different solvents like methanol, chloroform, 95% ethanol, acetone and dic...
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