Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
ENHANCEMENT OF SOLUBILITY AND DISSOLUTION RATE OF ERLOTINIB HYDROCHLORIDE BY SOLID DISPERSION TECHNIQUE WITH POLOXAMER 188: PREPARATION AND IN-VITRO EVALUATION
Solid dispersions (SDs) of Erlotinib hydrochloride (ETN) were prepared to enhance the solubility by solvent evaporation (SE) and Melting (MM) method using poloxamer 188 (PL 188) in the ratio of 1:1, 1:3 and 1:5 (w:w). The solubility of the drug was increased in a concentration-dependent manner of polymer and follow linearity order. The solid dispersion was characterized by Fourier transform infrar...
2081
797
THE EVALUATION OF VITAMIN C SUPPLEMENTATION ON NUTRITIONAL STATUS OF PATIENTS WITH ACUTE MYELOID LEUKEMIA UNDERGOING CHEMOTHERAPY
Background: Leukemia is the seventh common cancer in Iran, and AML is considered as the most common type. Malnutrition is common among patients with cancer. Vitamin C deficiency has a high prevalence among patients with cancer, which may influence a patient's survival chance. This study was aimed to evaluate the effect of vitamin C supplementation on nutritional status and serum albumin in patient...
1823
702
PHARMACOLOGICAL EVALUATION OF THE IN-VIVO ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF THE ESSENTIAL OIL FROM CYMBOPOGON OLIVIERI (BOISS.) BOR.
Cymbopogon olivieri (Poaceae) is a native plant to the south of Iran and is used for the treatment of some inflammative based disorders and as a pain killer. Regarding the presence of volatile terpenoids in the aerial parts, we were prompted to investigate the analgesic and anti-inflammatory activities of the essential oil from C. olivieri in animal models. The oil was also analyzed by GC and GCâ€...
1576
755
DESIGN AND CHARACTERIZATION OF SOME NEW NON-SYMMETRIC SUBSTITUTED TRIAZINES AND TRIAZINE DERIVATIVES
Attempts were made to carry out the laboratory synthesis of non-symmetric mono-, di- and tri- substituted 1, 3, 5-triazines by the action of the electron-donating substituent on 2, 4, 6-trichloro-1, 3, 5-triazines by aromatic nucleophilic substitution reaction mechanism (SNAr reaction) by temperature controlled. The introduction of the amino group (-NH-), ether (-O-) and thiol (-S-) Linker Bridge ...
1519
1260
ANTIFUNGAL ACTIVITY OF AMPHOTERICIN-B ETHOSOMAL GEL AGAINST CANDIDA ALBICANS: A COMPARATIVE STUDY
Amphotericin B is among the gold standard antifungal agents used for the treatment of the wide range of fungal infections. Work aimed to formulate the amphotericin B (AmB) ethosomal gel (EF), evaluate its antifungal activity against fungal isolates of human origin and compare its antifungal activity with marketed liposomal gel (MLG). AmB ethosomal gel (EF) was formulated and characterized for thei...
2136
835
THE PROTECTIVE ROLE OF RAPHANUS SATIVUS ROOTS IN REVERSING THE RENAL ALTERATIONS AND OXIDATIVE DAMAGE AGAINST STREPTOZOTOCIN INDUCED DIABETES IN RATS
Oxidative stress and hyperglycemia are two major factors implicated in the development of renal damage. Roots of Raphanus sativus have been reported to possess both ant diabetic and antioxidant activities. So, the present study was aimed to investigate whether aqueous root extract of Raphanus sativus (ARRS) is effective in reversing the renal alterations and oxidative damage against streptozotocin...
2088
842
A STUDY ON PARAMOUNTCY OF COGNITIVE PHARMACEUTICAL CARE IN DRUG-DRUG INTERACTION AMONG IN PATIENTS
Drug-drug interactions (DDIs) are known for their potential to cause adverse clinical outcomes, rate of morbidity and mortality. An integrated approach to cognitive pharmaceutical care (CPS) would decrease the incidence of DDIs in hospitalized patients. This prospective interventional study was carried out among the inpatients admitted to a tertiary care multispecialty hospital in Chennai. A total...
1585
778
SYNTHESIS AND MOLECULAR DOCKING STUDY OF BIOACTIVE QUINOLINO- BENZIMIDAZOLE DERIVATIVES
A series of some quinolino-benzimidazole/thiazole derivatives (3a-3h) have been synthesized from2-hydroxyquinoline-3-formaldehyde derivatives (1a-1d) and 1, 2-phenylenediamines/2-aminothiophenols (2a-2c). The synthesized compounds were characterized by FTIR, 1H-NMR and Mass Spectrometry. All the compounds were screened in-vitro for their antibacterial activity against Mycobacterium tuberculosis (H...
1470
712
PHYTOCHEMICAL SCREENING, SILVER NANOPARTICLE SYNTHESIS AND ANTIBACTERIAL STUDIES ON THE LEAVES OF AESCHYNOMENE ASPERA L.
Green synthesis is one of the best routes for the silver nanoparticles (AgNPs). The present study revealed that the aqueous leaf extracts of Aeschynomene aspera, which contains alkaloids, flavonoids, phenols, terpenoids, anthocyanidins, indoles, glycosides, saponins and tannins, is found to be responsible for bioreduction during the synthesis of silver nanoparticles (SNPs). The colour change from ...
1568
912
ISOTRETINOIN ANTI-ACNE GEL FOR THE MANAGEMENT OF P. ACNE INFECTION
The object of the paper is the development of anti-acne gel of isotretinoin and evaluated for as potential formulation to treat Acne vulgaris. The isotretinoin based anti-acne gel was prepared by using carbopol 940 polymers and evaluated for solubility, drug interaction, drug release, pH, viscosity and spreadability. In-vitro drug release through Franz diffusion cells, acute skin irritation test a...
2402
676