Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
THE POTENTIAL PROTECTIVE EFFECT OF STRAWBERRY EXTRACT AGAINST INDOMETHACIN-INDUCED LIVER TOXICITY AND GASTRIC ULCERATION IN RATS: BIOCHEMICAL, HISTOPATHOLOGICAL AND GENETIC STUDIES
The objective of this study was to determine the hepatoprotective effect of strawberry extract (150 mg/kg.b.w) in rats against Indomethacin sodium-induced gastric ulceration. Oral indomethacin administration (5 mg/kg.b.w.) resulted in a substantial rise in total plasma cholesterol, triglycerides (HDL), factor-alfa (TNF-α), nitric oxide (NO), liver and stomach necrosis, tumor necrosis factor-alfa ...
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ETHANOLIC SEED EXTRACT OF AFRAMOMUM MELEGUETA PROTECTS AND PRESERVES THE FUNCTIONS AND MICROARCHITECTURE OF THE OVARY OF ADULT FEMALE WISTAR RATS AGAINST PARAQUAT INDUCED TOXICITY
Aframomum melegueta (Alligator pepper) is a tropical plant that belongs to the Zingiberaceae (Ginger) family, consumed for its culinary and health benefits. This study investigated the therapeutic efficacy of ethanolic seed extract of Aframomum melegueta at ameliorating paraquat-induced ovarian toxicity in rat models. Thirty female Wistar rats were divided into control and five test groups (n=5). ...
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BIOAVAILABILITY ENHANCEMENT OF ACYCLOVIR USING HIGH-DENSITY GASTRO-RETENTIVE PELLETS
The objective of the present study was to improve the oral bioavailability using high-density gastro-retentive pellets containing solid dispersion of acyclovir. Solid dispersion prepared with polyvinylpyrrolidone (PVP K30) and hydroxypropyl methylcellulose (HPMC) using different ratios 1:1, 1:2, 1:3, 1:4, and 1:5 by solvent evaporation method and characterized for solubility study, dissolution stu...
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IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF SALIX ALBA L. ALONG WITH SIMULTANEOUS HPTLC ANALYSIS OF SALICIN AND FERULIC ACID
Now a day’s interest towards natural and has been growing due to the unhealthy consequences of chemicals in the health industry; though, herbal substances possess several quality control and confirm pharmacological action issues. This present study was designed to determine the effects of Salix alba L. methanolic extract (MESAL) for its antioxidant and anti-inflammatory activity in rat models. F...
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PHYTOCHEMICAL CHARACTERIZATION OF COLD MACERATED METHANOLIC LEAF EXTRACT OF CADABA INDICA LAM. USING GC-MS
Cadaba indica Lam (Indian Cadaba), an Indian traditional medicinal plant has been used for various diseases. The cold macerated methanolic leaf extract of Cadaba indica was assessed using Agilent GC 7890A gas chromatography connected with an MS- 5975C mass spectrometer and the mass spectra were matched with NIST 14.0 – data library. Several chemical constituents were identified within 28 min of ...
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SYNTHESIS, CHARACTERIZATION AND IN-VITRO ANTICANCER SCREENING OF VITIS VINIFERA SEED ETHANOLIC EXTRACT LOADED CHITOSAN NANOPARTICLES IN H-29 COLON CANCER CELL LINE
Nanotechnology can be applied to deliver and protect antioxidants in order to control the oxidative stress phenomena in several chronic pathologies. Chitosan (CS) and its carboxymethyl derivatives are smart biopolymers that are non-toxic, biocompatible, and biodegradable, and, hence, suitable for various biomedical applications, such as drug delivery gene therapy and tissue engineering. Vitis vini...
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ISOLATION OF PHYTOCONSTITUENTS AND EVALUATION OF JUSTICIA GENDARUSSA LEAF EXTRACTS FOR ANTI PARKINSONIAN ACTIVITY
The present study investigates the anti-parkinsonian activity of various extracts of Justicia gendarussa (JG) leaves in MPTP-induced neurotoxicity mice. Parkinson’s disease (PD) is a neurodegenerative syndrome belongs to a group of motor symptoms disorders. In PD, brain cells degenerated in some parts of the brain which produce dopamine. JG herb is widely distributed in tropical regions of the w...
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BIOTRANSFORMATION OF QUERCETIN BY ASPERGILLUS NIGER FROM ALLIUM CEPA
Biotransformation is a biological process in which the microbes are converting one form of compound to the another form. In the present research work, we studied about the conversion of Quercetinto kaempferol, which is having more therapeutic potential. Flavonoids are diverse group of secondary metabolites found especially in all plants. Flavonoids have Anti-carcinogenic, Anti-inflammatory, antiox...
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STRESS STUDIES OF METFORMIN AND GLICLAZIDE BY HPLC METHOD AND EXTENSION OF METHOD APPLICATION FOR ELUTION OF SOME ANTIVIRAL, ANTI-BACTERIAL AND ANTI-INFLAMMATORY DRUGS
A simple reverse phase SI-HPLC method was developed for the simultaneous estimation of antidiabetic combination of metformin and gliclazide. The method was based on HPLC separation on a reversed-phase C18 column using a mobile phase consisting of phosphate buffer: acetonitrile (40:60, v/v) at a flow rate of 0.8 ml/min. UV determination was achieved at 240 nm. The analytes were subjected to various...
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EVALUATION OF ANTI-PARKINSON’S ACTIVITY OF CYAMOPSIS TETRAGONOLOBA METHANOL PLANT EXTRACT WITH BEHAVIORAL AND BIOCHEMICAL ANALYSIS
In the present study, we evaluated the Anti-parkinson’s activity of Cyamopsis tetragonoloba methanol plant pod extract by Haloperidol Induced Catalepsy and Tacrine induced vacuous jaw movements for behavioral parameters and in-vivo assays to estimate neurochemical parameters like (GSH, LPO, and SOD). The behavioral analysis performed using Haloperidol Induced Catalepsy produces Parkinson’s dis...
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