Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PREPARATION AND IN-VITRO EVALUATION OF APREMILAST EFFERVESCENT FLOATING TABLETS
Apremilast, the new PDE4 inhibitor drug, exhibits low solubility and low permeability; therefore, shows variable bioavailability. Effervescent floating tablets of apremilast were developed to sustain the drug release rate by increasing gastric retention time. These tablets were prepared by wet granulation technique, using different polymers like carbopol 934P, hydroxypropyl methylcellulose K4M, tr...
1152
645
DEVELOPMENT AND EVALUATION OF GINGER TRANSDERMAL PATCH AND ITS IMPLICATIONS IN MIGRAINE THERAPY
The potential of transferosomal formulation for transdermal delivery of Ginger constituents was investigated. The aim was to reduce the dosage and improve patient acceptance. Transferosomes were formulated by ethanol injection technique using Phospholipids (Lipoid P-100), cholesterol, various edge activators (tween 80, Span 80), and other excipients. Transdermal patches were prepared by solvent ca...
1523
692
A NEW RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF TOLCAPONE AND QUINAPRIL IN ITS PURE AND PHARMACEUTICAL DOSAGE FORM
A short selective, precise, accurate, and sensitive method for the estimation of Tolcapone and Quinapril was done by RP-HPLC. The assay of Tolcapone and Quinapril was performed with tablets, and the % assay was found to be 100.19 and 100.45, which shows that the method is useful for routine analysis. The linearity of Tolcapone and Quinapril was found to be linear with a correlation coefficient of ...
862
410
FORMULATION AND EVALUATION OF NANOSTRUCTURED LIPID CARRIER FOR THE MANAGEMENT OF PSORIASIS
The objective of the research work was to design NLCs gel of Acitretin and perform an in-vitro evaluation of different formulations. FTIR and DSC studies revealed that there was no interaction between drug and polymer and with the respective surfactant. A new generation of NLCs consisting of a lipid matrix with a special nanostructure has been developed. These nanostructures improve drug loading a...
1321
676
2D QSAR ANALYSIS OF DIPEPTIDE NITRILE BASED CATHEPSIN S INHIBITORS
Cathepsin S enzyme has been considered as an evolving target for the development of novel therapeutic agents for the treatment of numerous autoimmune disorders and other inflammatory diseases. Using TSAR 3.3 2D QSAR has been performed on a series of dipeptide nitrile nucleus. Attempts have been made to derive and comprehend a correlation between biological activity and the generated descriptors. T...
1422
485
PHARMACOGNOSTIC STANDARDIZATION OF POLYHERBAL FORMULATION PALASHA BEEJADI CHOORNA
Herbs are the main source of Ayurvedic formulations. Polyherbalism concept of Ayurveda enables fortified therapeutic effect when compared to single herb. The potency of polyherbal formulations depends on their ingredients. Plants tend to vary in their efficacy due to the influence of environmental factors, such as temperature, humidity, light, oxygen, moisture content. The quality of polyherbal fo...
1218
715
TO STUDY THE EFFECT OF NATURAL POLYMER ON THE RELEASE OF OSMOTIC TABLET FOR COLON SPECIFIC DRUG DELIVERY SYSTEM
Controlled and targeted drug delivery system is more advantages than conventional dosage in various aspects. In the case of treating colonic disorders such as inflammatory bowel disease, the drugs do not reach the site of action in appropriate concentration. Thus there is a need to develop effective and safe therapy for the treatment of these colonic disorders, using site-specific drug delivery ap...
905
407
INVESTIGATION OF THE ANTI-CANCER POTENCY OF NANOMEDICINE, GREEN SYNTHESIZED FROM SPIRULINA PLATENSIS, AGAINST BREAST CANCER
Breast cancer is the most common type of cancer found in women. Although considerable advances have been achieved in the diagnosis and treatment of breast cancer, medical research routinely thrives towards the development of newer technologies for the treatment of breast cancer. The current study aimed at the development of nanomedicine, in the form of silver nanoparticles from the aqueous extract...
994
460
HEPATOPROTECTIVE ACTIVITY AND OXIDATIVE STRESS OF THE AQUEOUS EXTRACT OF SEED FROM PINTO BEAN (PHASEOLUS VULGARIS L.) IN STREPTOZOTOCIN INDUCED ALBINO WISTAR RATS
The aim of the study was to evaluate the anti-diabetic and antioxidant effects of aqueous extract of Phaseolus vulgaris L. seeds in normal and streptozotocin (STZ) induced diabetic rats. Female Albino Wistar rats were divided into 6 groups of 6 rats; each was assigned into diabetic and non-diabetic groups. Diabetes was induced in rats by single intraperitoneal administration of STZ (55 mg/kg body ...
1053
410
DEVELOPMENT AND CHARACTERIZATION OF SOLID LIPID NANOPARTICLES OF LINAGLIPTIN
The main objective of the present research work was to formulate and characterize the linagliptin-loaded solid lipid nanoparticles (SLNs). SLNs possess distinctive characteristics like small and spherical shapes with an average diameter between 1to 100 nm. Linagliptin is used for the treatment of type II diabetes and it is a dipeptidyl peptidase 4-inhibitor and its oral bioavailability is 30%. The...
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