Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME N’-(SUBSTITUTED BENZYLIDENE)-2-(7-BROMO-PHENYLQUINAZOLIN-4-YLOXY) ACETOHYDRAZIDE DERIVATIVES
Quinoline or 1-aza-naphthalene or benzo [b] pyridine is a weak tertiary base. In the study, the synthesis of compounds and their antimicrobial activity which is not done earlier and is quite significant. An attempt has been made for the synthesis of N'-(substituted benzylidene)-2-(7-bromo-2-phenylquinazolin-4-yloxy) acetohydrazide (5-15). The titled compounds were prepared by the reaction of bromo...
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ANTIOXIDANT AND ANTIMICROBIAL POTENTIALS OF THE EXTRACTS OBTAINED FROM THE FIVE MARINE SPONGES COLLECTED OFF THE COASTS OF AGUSAN DEL NORTE, PHILIPPINES: AXINYSSA SP, PLOCAMIONIDA SP, FORCEPIA SP, PACHYMATISMA SP AND PLACOSPONGIA SP
Five marine sponges were collected off Carmen, Agusan del Norte, Philippines and taxonomically identified as Axinyssa sp., Plocamionida sp., Forcepia sp., Pachymatisma sp and Placospongia sp. The “non-polar” (EtOAc-MeOH) and “pola”r (EtOH-H2O) extracts of the marine sponges were prepared and subjected to 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, a total antioxidant ca...
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SOLID STATE MANIPULATION OF TELMISARTAN VIA MECHANOCHEMICAL ACTIVATION WITH KAOLIN: AN ASSESSMENT OF BIOPHARMACEUTICAL PROPERTIES OF AMORPHOUS PHASE AND ITS PHYSICAL STABILITY
The objective behind this study is to investigate the affinity between a carboxylic model drug telmisartan and kaolin. Telmisartan was comilled in solid state with kaolin in different weight ratios and characterized by Fourier transform infrared spectroscopy, Differential scanning calorimetry, X-ray powder diffractometry, scanning electron microscopy to examine the extent of transformation from cr...
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STATISTICAL ANALYSIS ON EFFECT OF SITAGLIPTIN AND GLIMEPIRIDE ON PANCREATIC BETA-CELLS DURING THE TREATMENT OF TYPE-2 DIABETIC MELLITUS
The study aimed to analyze the treatment of Sitagliptin with Glimepiride to improve pancreatic beta-cells in T2DM patients. Beta cells are a type of cell found in the pancreatic islet and also synthesize, secrete insulin and amylin. Sitagliptin is found to be maintaining the beta-cells function and glycemic control in T2DM patients. Randomly diabetes mellitus type-2 (T2DM) patients’ data is coll...
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IN-VITRO CULTURE CHARACTERISTICS OF YOUNG AND OLD RAT MESENCHYMAL STEM CELLS
Mesenchymal stem cells are a small number of undifferentiated cells located in various tissues of the body. They have the ability to self-renew and differentiate into lineages of mesenchymal origin. They serve as most promising candidates for various regenerative medicine and tissue engineering applications. Their use in various clinical applications depend on their proliferative capacity to expan...
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IN-VITRO ANTHELMINTIC EVALUATION OF HIBISCUS ROSA-SINESIS (L) AND AZADIRACHTA INDICA (L) LEAVES AGAINST HELMINTH PARASITE OF THE GOAT: A COMPARATIVE STUDY
The comparative study designed to evaluate the anthelmintic potential of the methanolic extracts of Hibiscus rosa-sinesis (L) and Azadirachta indica (L) leaves against helminth: Haemonchus spp., an abomasal parasite For this study various concentrations (1, 2.5, 5.0, 10.0 mg/ml) of both the extracts were screened. 1 mg/ml concentration of Albendazole (ABZ) was used as a positive control (referen...
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EVALUATION OF ANTI-DEPRESSANT ACTIVITY OF ROFLUMILAST IN ALBINO MICE
Depression is a collective term used for the mental condition characterized by loss of interest, inability to concentrate, eat or sleep, reduced energy levels, together with reduced self-esteem. To date, the medicines available are often associated with several adverse conditions and fail to treat comorbidities it entails. Phosphodiesterase (especially its inhibitors) are recently gaining attent...
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SPECTRAL ANALYSIS AND HYPOGLYCEMIC EFFECT OF CRUDE SAPONIN EXTRACTED FROM PHOENIX PUSILLA ROOT
In this present study, the objective was to extract crude saponins from the root of Phoenix pusilla (PP) and to check its inhibitory potential of α- amylase and α- glucosidase enzyme. Saponins were isolated by partitioning between butanol and water. Further, the presence of saponin was confirmed by the foam test. Then the crude saponins were analyzed by UV- spectroscopy in the range of 200-400 n...
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PHYTOCHEMICAL EVALUATION AND STANDARDIZATION OF POLYHERBAL ETHYL ACETATE EXTRACT AND ITS GEL-BASED FORMULATION OBTAINED FROM BERRIES AND FLAXSEED (EAPEG-BF)
Berries, fruits, and flaxseed have nowadays have increased in research studies. The berries such as Rubus idaeus (Red raspberry), Vaccinium macrocarpon (cranberry), Vaccinium angustifolium (blueberry) and Fragaria x ananassa Duch. (strawberry) have health beneficial compounds like anthocyanins, ellagitannins, ellagic acids, polyphenolic compounds and whereas in flaxseed the polyunsaturated fatty a...
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SOLUBILITY ENHANCEMENT OF BCS CLASS II DRUGS
One of the major barriers in the development of oral dosage form is poor solubility. Poor water solubility obstructs drug bioavailability and decreases its pharmaceutical development. Many drugs are in the pipeline to enhance solubility to formulate dosage form to be taken by the most preferred route of administration that is the oral route. Etodolac is nonsteroidal anti-inflammatory drug having a...
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