Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 5.2 | 2.73 | 0.64 |
SCREENING OF MEDICINAL PLANTS USED FOR PREVENTION AND TREATMENT NEURODEGENERATIVE DISEASES: A REVIEW
Amyotrophic lateral sclerosis (ALS), Parkinson's disease, Alzheimer's disease, and Huntington's disease occur as a result of the neurodegeneration process. No specific treatment was found to reduce or stop neurodegenerative diseases. In conventional medicine, many plants have been used to treat neurodegenerative diseases. Natural products play an important role in the prevention and treatment of v...
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COMPARATIVE REVIEW OF MOMORDICA CHARANTIA AND MOMORDICA DIOICA: AN UPDATE
Momordica charantia and Momordica dioica species belong to the Cucurbitaceae family. Momordica charantia and Momordica dioica climbing creeper plants are used both in the prevention and cure of various diseases and in the food of humans. Momordica charantia is also known as bitter gourds, bitter melon, karela, and balsam pear. Momordica charantia contain phytochemical constituents such as alkaloid...
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THE ANTICANCER ACTIVITY OF BIOACTIVE COMPOUNDS FROM MEDICINAL PLANTS: AN REVIEW
Cancer is a serious health concern in both developed and developing nations. Cancer causes due to unwanted growth of cells and irregular cell division. Medicinal plants have been used by village folk from ancient times. The plants contain various bioactive compounds that can be used for treating cancer. Some of the phyto compounds isolated from plants have shown promising results; these include ...
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ANDROGRAPHOLIDE AND HESPERIDIN – A BRIEF OVERVIEW
Andrographolide is a labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata Nees (Acanthaceae). Andrographolide is isolated by various processes and the simple method is the maceration process. It is bitter in taste and used as hepatoprotective, cholinergic, antispasmodic, stomachic, anthelmentic, alterative, blood purifier, and febrifuge. It promotes the secretion of bi...
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PHARMACOLOGICAL STUDIES OF MEDICINAL PLANT CITRULLUS COLOCYNTHIS: A REVIEW
The medicinal plant Citrullus colocynthis is very significant for indigenous medicine. The pharmacological effects of root, fruits, seeds, leaves, and the whole C. colocynthis have been practices for the treatment of diseases. Phytochemical screening of the fruits of C. colocynthis has observed several bioactive compounds. The glycosides, flavonoids, alkaloids, carbohydrates, fatty acids, and esse...
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CYTOTOXIC AND ANTIPROLIFERATIVE STUDIES OF ISOCORDOIN AND SOME DERIVATIVES AGAINST PROSTATE CANCER CELL LINES
The proposed study was to evaluate the in-vitro cytotoxic and antiproliferative activities on prostate cancer cell lines of isocordoin (1) and 2’,4’-dihydroxy-3’-(g,g-dimethylallyl) dihydrochalcone (2), chalcones isolated from roots of Lonchocarpus xuul Lundel, together with four analogues of 1. Isolation of compounds 1 and 2 from L. xuul roots and chemical modification were in accordance wi...
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ANALYSIS OF THE EFFECT OF LOW DOSE DOPAMINE IN TREATMENT OF PRERENAL AZOTEMIA IN ADULT PATIENTS ATTENDING NEPHROLOGY UNIT IN NAUTH, NNEWI, NIGERIA
Background: This was a conventional comparative treatment-controlled study designed to analyze the effect of dopamine infusion in the treatment of prerenal azotemia (PRA). Material and Methods: thirty randomized consecutive adult patients (group A= 15, B=15) aged 18 and 58 years with PRA were recruited. Group a received conventional treatment only (fluid replacement and frusemide), while group B r...
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DESIGN AND EVALUATION OF CHRONOTHERAPEUTIC ANTI-HYPERTENSIVE COMBINATION THERAPY USING MINI-TABLETS TECHNOLOGY
Hypertension or elevated blood pressure (BP) is a serious medical condition that significantly increases the risks of heart, kidney, brain, and other diseases. In persons with normal BP and uncomplicated essential hypertension, BP falls to the lowest levels during the nighttime sleep, and rises suddenly with morning awakening, and reaches the peak during the initial h of diurnal activity. The opti...
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STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION OF REMOGLIFLOZIN ETABONATE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY RP-HPLC
An accurate, precise, and simple stability-indicating and RP-HPLC method was developed and validated for the estimation of Remogliflozin Etabonate in bulk and pharmaceutical dosage forms. Primacel C18 (150 × 4.6mm, 5µm) column, with mobile phase Acetonitrile: Water (70:30, v/v) at isocratic mode, was used for the development of this method. At wavelength 280nm, and flow rate of 1ml/min was maint...
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FORMULATION DEVELOPMENT AND EVALUATION OF NANOGEL LOADED WITH MONTELUKAST SODIUM NIOSOMES
Niosomes are vesicular carriers in the drug delivery system that are reported in the seventies. They are formed by self -assembly of non –ionic surfactant and cholesterol upon hydration with aqueous media resulting in lamellar structures that encapsulates both polar and non polar drugs. In the present research work, Montelukast sodium niosomes were prepared by using non –ionic surfactant span ...
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