Posted by admin on Sep 30, 2015 in |
Introduction: Drug related problems occur commonly in patients who often receive polypharmacy with multiple co-morbid conditions. This constitutes a major health problem because of their negative consequences with increased morbidity and mortality. Aims and Objectives: The aim of the study was to assess the impact of clinical pharmacist interventions in drug therapy in hospitalized diabetes mellitus patients with hypertension. Methodology: A Prospective interventional study was carried out in the medicine wards of a tertiary care teaching hospital over a period of 10 months from September 2013 to June 2014. The drug therapy details of the patients were collected from inpatient case records. Clinical pharmacist reviewed the drug therapy, identified the drug related problems during ward rounds and discussed with the physicians and suitable suggestions was provided which had been documented. Results: A total of 147 drug therapy problems were identified from 111 patient case records. The number of drug related problems was predominant in males than females. Drug related problems were commonly seen in patients aged between 61-80 years...
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Posted by admin on Sep 30, 2015 in |
Objective: Comparative screening of Polyherbal preparations for anti-diabetic and antioxidant activity in rats. Materials and Methods: The blood glucose lowering activity of the Polyherbal preparation 1and 2 was studied in normal rats and alloxan-induced diabetic rats after oral administration at doses of 1.0 ml/kg body wt. Blood samples were collected from the tail vein method on 1,7, 15, and 23rd day. Biochemical parameters like SGOT, SGPT, Liver Glycogen, Urea, Creatinine, LDL, Cholesterol etc were evaluated. Effect was also observed on antioxidant activity and learning and memory dysfunction in diabetes. The data was compared statistically using the one-way ANOVA method followed by the Dunnett test. Results: The Polyherbal preparation 1and 2 produced significant (P<0.05,0.01) reduction in the blood glucose level and other biochemical parameters in diabetic rats after 23 days of study compared with that of control and Metformin. They also have significant antioxidant activity effective in diabetic neuropathy and learning and memory dysfunction. Conclusion: The Polyherbal preparation 1 and 2 showed antidiabetic in diabetic rats. This preparation can be...
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Posted by admin on Sep 30, 2015 in |
The wood apple (Feronia limonia), called as elephant apple, has several medicinal properties. It is antiscorbic (prevent scurvy), a disease caused by lack of vitamin C (ascorbic acid). It is an antidote for poison and also helps in curing sore throat. The objective of the study was to incorporate medicinal properties of wood apple in fruit bar, a well accepted food product. The fruit bar was prepared by using different proportions of wood apple and mango. Fruit bars were analyzed for chemical composition at monthly interval of one month storage at room temperature (16-35°C). Increasing trend in carbohydrate, acidity, TSS and reducing sugar was observed where as decrease in ascorbic acid, pH and total sugar was noted throughout the storage period. Organoleptic qualities of wood apple mango blended bar (50:50) were evaluated in comparison with control sample (wood apple fruit bar). The results on sensory parameters indicated that blended bar was superior in most of the quality attributes. Storage upto six months could be possible with wood apple mango...
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Posted by admin on Sep 30, 2015 in |
Clinical pharmacists are integral part of patient healthcare team. They tend to serve as key element in patient care provide quality of care to reduce ADR (adverse drug reactions),improve patient compliance, effective drug cost and make role of pharmacist evident in healthcare sector and society. For the purpose of evaluating patient outcome failure from treatment, a retrospective study conducted where clinical pharmacist were directed to pay their role in evaluating mechanism behind failure of treatment. About 300 patients from different healthcare sector were included particularly of with chronic illness and those reported with poor compliance. They disclose many horrible facts and identify mechanism in poor response of therapy. By special counseling in separate area by clinical pharmacist patient reveals many fact in failure about 31% due to improper counseling, 61% undesirable taste, 5% ADR,41% due to psychological burden of long treatment and only 11% were receiving psychological treatment with 59% were not satisfied with physician response. After introduction of clinical pharmacist, there is a remarkable improvement in outcome of...
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Posted by admin on Sep 30, 2015 in |
The non-invasive adhesive tape stripping technique was used to evaluate dermato-pharmacokinetics of nanometric titanium dioxide in tropical albinistic skin. Ten sequential strippings were conducted on exposure sites on the forehead, inner and upper forearms of three oculocutaneous albinism individuals 26+/- 4 years old, 15 minutes post dosing of 6.75mg/cm2 of a 5% titanium dioxide cream specifically designed to retard actinic damage in albinistic persons. The strips were subsequently acid treated and analyzed for titanium content by ICP-AES. All the applied titanium was recovered from the surface and upper layers of the stratum corneum of all participants from all body sites. The average recovery of titanium was 98.50± 0.66%.No titanium was detected in strips 9 and 10 from all sites. On the inner forearm, on average 67.92± 0.95% titanium was localized on the surface (strip1and the cotton swab), 29.41± 0.60%was recovered in the upper stratum corneum strips 2-5. The small remainder was recovered from the lower strippings. On the upper forearms the average recoveries were 61.86± 0.72% Ti (surface), 34.29±...
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