Posted by admin on Sep 30, 2015 in |
The effects of AM fungi on Salvia miltiorrhiza under different selenium levels was researched using pot technology. The results showed that inoculation of AM fungi significantly increased the plant height, root length, each part weight, chlorophyll, protein and selenium content of Salvia miltiorrhiza under the same selenium level, in addition, MDA and proline contents decreased significantly. It can be seen that AM fungi could promote the growth of Salvia miltiorrhiza, enhance disease resistance and improve the uptake of nutrient elements. The contents of tanshinone IIA in inoculated plants were higher than non inoculated plants. While the selenium concentration was 40μg.ml-1, the content of tanshinone IIA in inoculated plants was highest, that was 0.272%. The growth of Salvia miltiorrhiza, soluble sugar, MDA and the content of tanshinone IIA increased firstly and then decreased, but the contents of inoculated plants were higher than non inoculated plants, they reached the maximum at Se1(20μg.ml-1)~Se2(40 μg.ml-1). From that proper concentration was cooperated with AM fungi on improving the growth and accumulating of medicinal components....
Read More
Posted by admin on Sep 30, 2015 in |
Background: Periodontal disease is one of the two main and most prevalent oral diseases all over the world. Treatment strategies are diverse. To date, scaling and root planing (SRP) is still the gold standard non-surgical therapy for periodontitis. Systemically administered antibiotics can be used as an adjunct to SRP to improve the treatment outcome of periodontitis. Purpose: To compare clinical outcome of systemically administered doxycycline versus combination of amoxicillin and metronidazole as an adjunct to SRP in the management of chronic periodontitis patients. Methods: This study was conducted on forty-two moderate to severe generalized chronic periodontitis patients who received non-surgical periodontal therapy. Following SRP, patients were randomly allocated to one of the following groups; group (I) received Doxycycline (loading dose 200 mg and maintenance dose 100 mg/day) for fifteen days, group (II) received a combination therapy of amoxicillin and metronidazole (750 mg/day) for eight days and group III (control group) which was treated by SRP without administration of systemic antibiotic therapy. The periodontal parameters; Plaque index (PI), Gingival index...
Read More
Posted by admin on Sep 30, 2015 in |
Cordia obliqua Willd var. obliqua. is a medium sized, broad leaved deciduous tree. It is found growing not only all over Asia but nearly the whole of the globe. Cordia obliqua (F. Boraginaceae) is traditionally used against fever, chest disease, leprosy, gonorrhoea and helminthes. Bark is bitter, mild astringent and tonic and used in general debility and convalescence. Decoction of the bark is used as a gargle in sore mouth. Juice obtained from the bark relieves severe colicky pains. Bark is anthelmintic, constipating, cooling, depurative and used in vitiated conditions of kapha, pitta and leprosy. In view of its medicinal importance, a complete study on macroscopic, microscopic characters and analytical parameters of stem bark have been made and presented. Histological studies were conducted by infiltration method. Anatomical features of the bark were studied using transectional, radial and tangential longitudinal sections. Powder characters were analysed and micrometrial measurements of the cells/tissues were carried out. Analytical parameters include ash values, extractive values and crude fibre content. Findings of this work are...
Read More
Posted by admin on Aug 31, 2015 in |
Background: Plants are enriched with various types of phytoconstituents present in the form of secondary metabolites that ensure its medicinal value. Keeping this in view, the present investigation was carried out focusing on its antioxidant property that may mainstay of exploring other therapeutic potency. Hence, phytochemical investigation followed with antioxidant property was evaluated in the leaf extracts of the selected plant Canthium coromandelicum (Burm.f.) Alston, collected from eastern coastal belt of south Odisha. Objective: To carry out the phytochemical studies of various leaf extracts and fractions of Canthium coromandelicum (Burm.f.) Alston. In vitro antioxidant activities were also estimated to justify the leaves being used in traditional medicine as an antioxidant. Methods: In vitro antioxidant activity was assayed by DPPH scavenging activity and 2-deoxy-D-ribose degradation. Estimation of total phenolic content and total flavonoid content were done. Further HPTLC finger print of active fractions was performed to isolate and purify the active components presence in them. One of the isolated purified compounds was characterized by various spectral methods. Results: Preliminary phytochemical...
Read More
Posted by admin on Aug 31, 2015 in |
A novel approach was tested utilizing mucoadhesive in-situ gelling (ISG) Gellan Gum /HPMC solutions containing dispersions of methazolamide (MZA) loaded Spanlastic Vesicular systems (SVs). The tested systems were designed to combine high corneal permeability of SVs as well as ease of application and prolonged eye retention of ISGs. SVs consisted of Span 60 mixed with different ratios of edge activators (EA) (Tween 60, Tween 80, Brij 35 and Brij 58) were initially prepared and examined to select formulae that had small vesicle size and high drug entrapment. The evaluation of SVs systems included measurement of particle sizes, entrapment efficiencies (EE %) and relative deformability. SVs in ISG systems were characterized by in vitro release, viscosity, intraocular pressure (IOP) measurement after their administration to rabbit eyes and histopathological examination. It was found that SVs containing 10% Tween 60 (90:10) in ISG solutions (SG1) produced the highest reduction in IOP with the highest prolongation of MZA...
Read More
