Posted by admin on Feb 25, 2015 in |
The complexes of Ru(III) having general formula [Ru(L)Cl(PPh3)] where L= azo Schiff base derived from 2-aminopyridine, 2-hydroxy naphthaldehyde /vanillin and ethylene diamine have been synthesized. The ligands as well as complexes have been characterized by elemental analysis, molar conductance, magnetic susceptibility, infra-red and electronic spectral data. The azo Schiff base ligand acts as a tetradentate ligand co-ordinating to Ru through azomethine nitrogen and phenolic oxygen atoms. An octahedral geometry has been proposed for the complexes based on electronic spectra and magnetic susceptibility studies. Low molar conductance values revealed the non-electrolytic nature of the complexes. The complexes have been screened for antimicrobial and anticancer...
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Posted by admin on Feb 25, 2015 in |
The plants used for the present study viz., Psidium guajava L and Citrus aurantium belong to the family Myrtaceae and Rutaceae respectively. Guava is native to tropical America. The young leaves are used as tonic in digestive disorders. Bitter orange is native of South Eastern Asia; grow in Tamil Nadu, Karnataka, Maharashtra, Punjab and Uttar Pradesh. It is a rich source of provitamin A. The present investigation on the fluorescent characters of the leaf powder showed varied colours like green, pale green, dark green, brown and yellow under different chemical treatments in both the medicinal plants used for the...
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Posted by admin on Feb 25, 2015 in |
The present communication is mainly focused to study the antioxidant activities of the four different extracts (benzene, chloroform, acetone and methanol) of five algae including Aphanothece pallida, Anabena variabilis, Aphanothece saxicola, Lyngbya major, Nitella flagelliformis. The total phenolic content varied from 2.99±0.23 to 25.38±0.22 mg/g, 4.20±0.135 to 14.10±0.13 mg/g, 3.07±0.22 to 27.03±0.11 mg/g and 2.34±0.03 to 4.87±0.14 mg/g dry material in the benzene, chloroform, acetone and methanol extracts of the algae respectively. The flavonoid content and flavonol content were found to be highest in the chloroform extract of Nitella flagelliformis and the least amount of flavonoids present in the acetone extract of Lyngbya major (4.88 ± 0.14 mg/g). The 1, 1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging effect of the extracts were determined spectrophotometrically. The highest radical scavenging was observed in the acetone extract of Nitella flagelliformis with IC50 = 0.15±0.01 mg dry material. The greater amount of phenolic compounds leads to more potent radical scavenging effect as shown by the acetone extract of Nitella flagelliformis. The reducing power of the...
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Posted by admin on Feb 25, 2015 in |
In this investigation, Miconazole Nitrate topical gels were designed by employing various bioadhesive polymers like polyacrylates (carbopol 940), cellulose derivatives (hydroxyl propyl methyl cellulose and sodium carboxy methyl cellulose) and natural polymers (sodium alginate) alone and in combination. The prepared gels were also characterized for different parameters like visual appearance, pH, consistency, rheological studies, drug content, in vitro release studies, stability studies and antifungal activity. From the results it was found that all the formulations were free of gritty particles and were found to be uniform in consistency. The values of pH were within the range of the skin pH that is in between 5.9 and 6.8, which indicates these gels cannot cause any local irritation to the skin surface. The consistencies of the gels were found to be excellent. The viscosity values of the gel increased in the following manner: carbopol and HPMC >carbopol>carbopol and SCMC >carbopol and sodium alginate > Sodium alginate >SCMC: indicating that carbopol in combination with HPMC was found to be the most viscous...
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Posted by admin on Feb 25, 2015 in |
Complexes of Co(II) with macrocylic ligands i.e., 2, 3, 9, 10 tetraphenyl – 1, 4, 8, 11 – tetraazacyclotetradeca – 1, 3, 8, 10 tetraene (BDP), 2, 4, 10, 12 – tetramethyl – 1, 5, 9, 13 tetraazacyclohexadeca 1, 4, 9, 12 tetraene (ADP), 2, 3, 9, 10 tetramethyl 1, 4, 8, 11 tatraazatetredeca – 1, 3, 8, 10 tetraene (DDP) have been synthesized. All these complexes were characterized by elemental analysis, molar conductance magnetic susceptibility measurement, electronic and epr spectral studies. On the basis of elemental analysis the complexes were found to have composition CoLX2. Molar conductance measured in DMF solution indicates that complexes are non-electrolytic in nature except Co(BDP)SO4 which are 1 : 2 electrolytes. Thus the complexes may be formulated as [CoCLX2]. Magnetic moments and the electronic spectra indicate six coordinated distorted octahedral geometry for the complexes. The ligand field parameters were calculated using various energy level diagrams. In vitro synthesized compounds and metal salts have also been tested against same species of plant pathogenic fungi...
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