Posted by admin on Sep 1, 2014 in |
Objective: To investigate the patient’s knowledge of hypertension fact with validated Morisky questionnaires and management of drug adherence. Materials and Methods: The aim of one present study was undertaken 100 patients attending the cardiology, outpatient department in various private sector hospitals in southern Tamilnadu and to assess the patient’s medication knowledge and drug adherence on hypertension with validated questionnaires method. Results: Out of 100 hypertensive patients (17%) of the subjects had adequate, (21%) of the patients had moderate medication knowledge about hypertension or maximum while (62%) were categorized as poor medication and adherence 35% of the people are in medium adherence only 3% are in high adherence. Conclusion: The disease knowledge of subjects’ rate was low, and patients were unsure of the benefits of continuous medication use and resulted in non-adherence. Educating hypertensive patients clarifying doubt regarding the benefits of adherence, medication uses, and control...
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Posted by admin on Sep 1, 2014 in |
The present study was carried out to investigate the protective effect of ethanolic extract of Madhuca latifolia (Roxb.) bark (MLE) and aqueous extract of Madhuca latifolia (Roxb.) bark (MLA) in aspirin-induced gastric ulcer. In both extract, acute toxicity performed according to guidelines for the selection of doses. The oral administration (400 mg/kg) of MLE & MLA extract reduced the ulcer index and prevents the development of gastric lesions by 76.57% and 81.14% (% of protection), respectively. The present studies provide preliminary data on the antiulcer potential of bark and support the traditional uses of the plant for the treatment of gastric...
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Posted by admin on Sep 1, 2014 in |
Aripiprazole is an anti-psychotic drug used in the treatment of psychosis, including schizophrenia, and during process development for Aripiprazole, we observed two related substances. This paper describes the preparation, identification and proposed structures of the impurities 7-(4-(4-(2-chlorophenyl) piperazine-1-yl) butoxy) – 3, 4 – dihydroquinoline – 2(1H) – one and 7- (4-(4-(3-chlorophenyl)piperazin-1-yl) butoxy)-3,4-dihydroquinoline-2(1H)-one formed during reaction of 7-(4-bromobutoxy)-3, 4-dihydroquinoline-2(1H)-one with 1-(2, 3-dichloro phenyl) Piperazine Hydrochloride to form...
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Posted by admin on Sep 1, 2014 in |
Background: High blood pressure has emerged as a leading cause of death and disability worldwide.1 Management of hypertension effectively has been a distant reality. Hypercum, a rationale combination of herbs has shown to reduce BP effectively along with other benefits as studied in the ancient literature and research publication. Objectives: The study aims to evaluate the safety and efficacy of “Hypercum” on mild to moderate hypertension, an open-labeled nonrandomized proof of concept study enrolled 16hypertensive associated with co-morbid conditions. Methods: patients who met the selection criteria. The efficacy was assessed by measuring the blood pressure at baseline and on every 15 days till the BP got controlled and then every month and followed up for 84 days. The effect of Hypercum on other co-morbid conditions was also evaluated. The quality of life was also assessed using SF-30. Planned student‘t’ test was applied. Results: At screening (before the enrollment for the study), the mean systolic blood pressure (SBP) was 161.25 mmHg, and their mean diastolic blood pressure (DBP) was 106.88...
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Posted by admin on Sep 1, 2014 in |
Endangered Indian medicinal plants have used as traditional and alternative Indian system of medicine (ISM) from last several ancient time. In 20th and 21th – century generation are becoming aware of the side effect and adverse reaction of synthetic drugs and so there is an increasing interest, Scope of innovating in herbal medicinal plants based Ayurvedic, Siddha, Unani (ASU) medicinal products. In the continuously using of Adulteration and Substitution, Spurious drugs on the place of original Indian endangered and costly ASU. Herbal medicinal plants hence today generate the major task of Indian drug regularity affaire, drug controlling approach, as well as herbal industries, face the burning problem. Resulted growing high altitude region many endangered and rare, costly original medicinal species such as these are Vatsnabh, (Aconitum Chasmanthumstapfex. Haimes), Ativishaor Atis, (Aconitumheterophylum Wall. Ex. Royal), Kutki, (Picrorhiza kurroa royleex), Kuth or Kustha, (Saussurea lappa C.B.CL.), Puskarmool, (Inularacemosa Hook.F.), Riddhi, (Hobenariainte media D. Don), Vriddhi, (Habenariaedge worthii Hook.f.ex.Collett), Kakoli, (Roseea purpurrea Smith), Kshirakakoli, (Fritillariar oylei Hook) and (Lilium polyphyllum D. Don),...
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