Posted by admin on Dec 1, 2013 in |
Zanthoxylum rhetsa DC. shoot is highly priced and one of the most preferred folk vegetable among the Indigenous people of Arunachal Pradesh, India. It is also used as folk medicinal purpose among the Adi tribe of the state. The methanol extract of shoot were evaluated for total phenolic content (Folin-Ciocalteu’s method), total flavonoid content (colorimetric method) and antioxidant potential ((DPPH & ABTS). Folk use, various mode of cooking, demand as vegetable in the local market is also discussed in this paper. The methanol extract contains considerable phenolic (117.95±3.22 mg GAE/g) and flavonoid (120.14±2.31 µMRE/g) with no much significant correlation between the total content of phenolic and flavonoid and antioxidant potential was found as IC50 value of 271±3.5µg/ml were recorded in ABTS assay and IC50 value of 306± 4.21µg/ml was found in DPPH...
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Posted by admin on Dec 1, 2013 in |
Phytochemical, HPTLC and Heavy metal analysis of Leaf of Leonotis nepetaefolia was done. Qualitative phytochemical screening of Leaf was done using different solvents which showed the presence of various vital secondary metabolites. Neutraceutical studies revealed the presence of carbohydrates, proteins and aminoacids. HPTLC studies confirmed the presence of flavonoids, diterpene, phenolic class of compounds. Heavy metal analysis showed the presence of Lead, Cadmium, Chromium and copper in all the samples...
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Posted by admin on Dec 1, 2013 in |
The present study is carried out with the methanolic extract of leaves of Millettia pachycarpa benth. Traditional use of it inspired us to investigate the blood corpuscular protective power of this plant as it used as blood tonic in Chinese traditional medicine. By the phytochemical screening we have both flavonoids and steroids. There’s also alkaloids are found which have extensive physiologic action embodying analgesic activity. This investigation is made following the most simple, reliable and less time consuming method. As the human red blood corpuscular membrane is similar to lysosomal membranes that influence inflammatory process. Result obtained using methanolic extract of M. pachycarpa have better acceptance as it shows good response in inhibiting hemolysis (34.30%) at highest concentration and these investigation surely stimulate further screening and isolation...
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Posted by admin on Dec 1, 2013 in |
An attempt was made to formulate and evaluate the 18-β-glycyrrhetic acid (GA) transdermal drug delivery system. Preformulation studies on the drug 18-β-glycyrrhetic acid were done which included description, solubility and compatibility studies. Solvent casting technique was used to prepare the transdermal patches. Four formulations were made with 400mg of 18-β-glycyrrhetic acid and by using polymers Hydoxypropyl methylcellulose (HPMC) and Ethyl cellulose (EC) with different concentration of menthol (2%, 5%) as penetration enhancer. Interaction of drug and polymer was confirmed by FTIR studies. Transdermal patches were evaluated for the weight, thickness, percentage moisture uptake, folding endurance, water vapor transmission rate, in-vitro release and in-vivo release studies. This was done for four formulations F1, F2, F3, and F4. The F1 formulation showed a good release profile due to increase in concentration of penetration enhancer. The accelerated short term stability study indicated that the optimized formulation F1 has very good stability at 4 o / 40 o / 60 o for a period of 3...
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Posted by admin on Dec 1, 2013 in |
Herbal medicine refers to the use of any plant’s seeds, berries, roots, leaves, bark, or flowers for medicinal purposes. Kalanchoe pinnata is known as herbal medicine that having many special advantages. The objective of the study was to scientifically assess antimicrobial activity of 95% ethanolic, methanolic, 60% methanolic and aqueous extract of leaves from Kalanchoe pinnata on Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. It was found that 60% methanolic extract shows best result. The 60% methanolic extracts of the selected plants leaves were taken in different ratio randomly and antimicrobial tests were carried out. The most effective concentration was then determined by comparing the results of the zone of inhibition. Phytochemical screening of 60% methanolic extract was carried out and the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) was found significant activity against microorganisms. The literature survey show that this plant leaves has only antibacterial activity. But with this research it is conclude that the plant leaves not only have antibacterial activity but also antifungal...
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