Posted by admin on Apr 1, 2013 in |
The antimicrobial and antioxidant activity of four different solvent extracts of P. florida were investigated. The antimicrobial activities of different solvents were tested against different bacteria and fungi using disc diffusion method. Total antioxidant, reducing power and total phenolic content effect of the extracts was determined by phosphomolybdenum assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and Folin-Ciocalteu method. Results indicated that the maximum antibacterial and antifungal activity was observed in ethanol extract of P. florida was found at 23 mm and 20mm against Streptococcus sp and E. floccosum respectively. Ethanolic extract of P. florida produced minimum inhibitory concentration (MIC) at 25mg/ml against E. coli followed by K. oxytoca (25mg/ ml), P. murabilis (75mg/ml) and Streptococcus sp. (50mg/ml). The ethanol extract exhibited good antioxidant activity (230 µg equivalent of BHT/g), strongest reducing power inhibition (79.24%) and also contain high phenolic content (6.25 mg gallic acid/g of dry extract). The results provided evidence that the ethanolic extracts of P. florida might indeed be potential sources of natural antioxidant and antimicrobial...
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Posted by admin on Apr 1, 2013 in |
Cow urine therapy and all traditional practices from Indian systems of medicine have a strong scientific base. The cow has proved to be a boon in the areas of agriculture, science and technology, industry, energy, medicine etc for the development of any nation, in addition being eco-friendly in nature. In the present study the antibacterial potentials of cow urine were investigated. Total 14 pathogenic and non-pathogenic bacterial cultures were used as test organism against 10 different cow urine samples. The highest zone of inhibition was shown by sample G against P aeruginosa NCIM 2945 (1.8cm) while the smallest zone of inhibition was shown against E. coli NCIM 2065(0.3 cm) by sample A. Based on cumulative effect against the test organism, the urine sample G was found to be the most efficient inhibiting all the 14 test cultures. The antibacterial activity reported by sample G was comparable with standard antibiotics. A higher zone of inhibition was observed by sample G against P aeruginosa NCIM 2945 as compared to that of...
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Posted by admin on Apr 1, 2013 in |
Impacts of sodium and potassium in diet to determine offspring gender in hamsters have been investigated. Sex determination has scientific basis for prevention of genetic diseases in addition to social backgrounds.20 healthy hamsters chosen from the first generation of the previous experimental hamsters, were divided in to two groups in the hamsters male to female 1:5. The first group was Na and K, the second group was control unit without Na and K. It was found that the delivered offsprings male to female ratio were 2.06:1and 1:1, for the first and second groups respectively. Also, it was found that hamsters fed with (Na, K) food yields, numbers of offspring (135), while hamsters fed with normal food yields, numbers of male offspring...
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Posted by admin on Apr 1, 2013 in |
We have synthesized some new pyridazine-3-one derivatives and characterized by means of IR, NMR & mass spectral data. Compounds were evaluated for in-vitro antibacterial activity by disc diffusion method and further subjected to molecular properties prediction and drug-likeness by Molinspiration software. All compounds were found in compliance with Lipinski ‘Rule of Five’ and presented a good drug-likeness score with no violations. Compound I and IV having substitutent (6-phenyl, 6-chloro phenyl) has documented good antibacterial activity against S. aureus & S. epidermidis. Compound III & V (4’-chloro-benzylidine, 4’-methoxy-benzylidine)has reported good activity against P. aeruginosa & E....
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Posted by admin on Apr 1, 2013 in |
Fertility was tested in 0.5 mM/kg b. wt. (i.p) Lanthanum chloride exposed mice. Beneficial effects of “Fortege” an ayurvedic medicine (Alarsin co. Bombay) were also tested. Lanthanum chloride affected sperm count and motility. Lanthanum chloride could have affected Sertoli cells adversely and that have reduced sperm’s ability of uptake of fructose and as a result of it sperms became unable to reach ovum and thus antifertility was shown. Maximum effects of Lanthanum chloride were on the weight of seminal vesicles and their fructose content. When such mice were exposed to “fortege” for 21 days and the efficacy obtained, was 87.5%. Only way to overcome Lanthanum toxicity is to remove Lanthanum from the tissues. For the removal of Lanthanum from the body tissues, the chelating activity of some alkaloids of these plants can be considered as the one of the main reason and it is supplemented by improvement in testosterone and LH...
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