Posted by admin on Aug 1, 2013 in |
Aim: The present study investigates the effect of Ramipril on blood sugar level and interaction with the oral anti-diabetic drugs in alloxan induced diabetic rats. Method: Rats were divided into 10 groups (n = 6) where Group I –II were normal and Group III –X were diabetic. Ramipril at the dose of 0.9 mg/kg body weight were administered to the normal and diabetic rats. In diabetic groups, the Ramipril was given concomitantly with the each of three Oral anti-diabetic drugs to find-out the effect on blood sugar level .All drugs administered orally once a day for 13 days and at the end of the experimentation Oral Glucose Tolerance Test (OGTT) was conducted. Results: It was observed that in normal rats the Ramipril slightly reduced the blood sugar level which was insignificant (P>0.05) except at ‘30’ min time point. In contrast in, it exhibited the anti-hyperglycemic activity significantly (P≤0.01) at all-time points in alloxan induced diabetic rats. Conclusion: The present study has concluded that The Ramipril has significant anti-hyperglycemic activities...
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Posted by admin on Aug 1, 2013 in |
Aim: Cellulite treatment incorporates iso-slim complex to reload the skin with minerals and trace elements to achieve absolute effectiveness in treating cellulite condition. The revitalizing effect of anticellulite helps to refine and reshape the silhouette and give the body a more toned, defined and firmer appearance. Aim of present work was to develop and investigate a novel delivery system for the fatty skin in the form of liposome delivery system. Method: Phosphatidylcholine, Cholesterol and iso-slim complex were dissolved in chloroform/methanol (2:1, v/v) mixture and subsequently transferred into a pear-shaped flask connected to a Rotavapor (Buchi- type). Rotary evaporation method was used for the formulation of liposomes. Result: Liposome prepared was evaluated for particle size measurement, percent drug entrapment, formulation of dosage forms, Stability Study and in vivo study. Optimized batch had particle size 18.62 um, percent drug entrapment 96.70%. Hence, optimized was batch further evaluated for in vivo study and stability study. Conclusion: The present study has been a satisfactory attempt to formulate and evaluate liposome of iso-slim complex...
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Posted by admin on Aug 1, 2013 in |
The common cause of leg ulceration in Western countries is venous disease of the lower limb.Venous insufficiency causes appreciable disability. Venous ulcer is one of the most prevalent diseases in the western countries and India, which can hamper personal and professional life of individual. After various methods of modern medicinal treatment and management there is a chance recurrence .This case study is a prospective and intervention to combat long standing & recurring venous ulcer aided by...
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Posted by admin on Aug 1, 2013 in |
Ayurvedic formulations are used to treat a wide variety of diseases including Diabetes Mellitus Standardization of Herbal Formulation is Essential in order to assess the Quality of drugs. The Present Study Reports for Standardization of Eight Herbal Anti-diabetic drugs- Momordica charantia (seeds), Syzigium cumini (seeds), Trigonella foenum (seeds), Azadirachta indica (leaves), Emblica officinalis (fruits),Curcuma longa (rhizomes), Gymnema sylvestre (leaves),Pterocarpus marsupium (heart-wood) individually and in the form of Polyherbal marketed samples of Baidyanath Madhumehari Churna, Shivayu Madhuhari Churna and were compared to the in-house preparation for Physicochemical properties as per WHO Guidelines. The Limits obtained from the different Physicochemical Parameters of the individual Eight Herbal drugs and the Marketed Formulations could be used as Reference Standard for Standardization of the Anti-diabetic drugs in a Quality Control...
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Posted by admin on Aug 1, 2013 in |
Various medicinal properties have been attributed to natural herbs. The use of traditional medicine is widespread in India. These herbal remedies are an important source for the discovery of new antimicrobials against the resistant strains of bacteria. Asavas and Arishtas are specially prepared ayurvedic medicines. They are alcoholic solutions containing all the active ingredients of the drugs of which they are compounded. Asavas are prepared by using herbal juices or herbs soaked in water while Arishtas are prepared by decoction. Different parts of medicinal plants are used traditionally for the preparation of specific asava or arishta that is effective against specific disorder. About 25 different medicinal plants commonly used were selected. Dried powders of these plants were extracted in water. The antibacterial activity of the extracts were then tested by agar well diffusion method against standard cultures of Escherichia coli, Klebsiella aerogenes, Proteus vulgaris, Salmonella typhimurium, Staphylococcus aureus and Bacillus thuringenesis. The individual extracts of Emblica officinalis, Terminalia chebula, Terminalia belerica andWoodfordia fructicosa, Jaggery were active against the test...
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