Posted by admin on Mar 1, 2013 in |
Time dependent density functional theory (TDDFT) calculations have been carried out to study the electronic structure and the UV absorption spectra of Triamterene. The UV spectra have been investigated with inclusion of solvent effect. The B3LYP functional with a 6-31G(d, p) basis sets have been used to compute absorption energies. The solvent effects have been described within the polarizable continuum model (PCM). The geometries are optimized using density functional theory (DFT) with B3LYP functional combined with 6-31G(d, p) basis sets. The vertical absorption energies both in gas phase and in polar solvents such as ethanol, methanol and water were computed. Red-shift of the absorption maximum in the polar solvents is discussed in terms of electrostatic interaction energy, oscillator strength and dipole...
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Posted by admin on Mar 1, 2013 in |
The focus of this exploratory study was to determine if community pharmacists order laboratory tests, why they order the tests, type of tests they order and what they do with the outcome of such tests. Self-administered pre-tested 34-item semi-structured questionnaires were used to carry out this study among superintendent pharmacists’ of registered pharmacy premises in two south-western states in Nigeria. Descriptive statistics (frequency and percentages), Mann-Whitney U and Kruskal-Wallis tests were used to appropriately summarize the data obtained. All the respondents who consented to take part had ordered laboratory tests for patients prior to this study. The types of invasive and non-invasive tests ordered, ranged from simple dipstick pregnancy test to more varied tests like: fasting blood glucose 24(36.9%), blood pressure measurement 58(89.2%), malaria parasite test 47(72.3%), full blood count 16(24.6%), widal reaction test 45(69.2%), urinalysis 10(15.4%) mantoux test 3(4.6%) and hepatitis B & C test 3(4.6%). Some of the perceived benefits derived from interpreting laboratory test results were patient trust and confidence in pharmacists 28(43.1%), job satisfaction and...
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Posted by admin on Mar 1, 2013 in |
A series of some new Isoxazoline derivatives derived from 3-(4’-dimethylamino-phenyl)-1-(2-hydroxyphenyl)-Propenone(chalcone) derivatives using hydroxylamine hydrochloride is reported. These newly synthesized compounds were screened for their antimicrobial potencies which reflect moderate to good activity against different strains of bacteria and fungi employed. The promising feature of this reaction is mild reaction condition and excellent yield with high purity of compounds synthesized. All the synthesized compounds were confirmed by IR, 1HNMR and...
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Posted by admin on Mar 1, 2013 in |
In this study, the antioxidant capacity during UV exposure has been investigated by using a laser-based trace gas detector for the detection of gaseous ethylene as an indicator for lipid peroxidation. Biocream was used as a control and ascorbic acid, butylated hydroxytoluene, phloroglucinol and hydroquinone were added as antioxidants in a mixing concentration of 2.5% (w/w). The experimental results show that there is a decrease in the number of ROS due to the presence of antioxidants, from which ascorbic acid is the most effective. The detection method offers a direct and on-line way to evaluate the capability of antioxidant in reducing the harmful effect of the UV...
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Posted by admin on Mar 1, 2013 in |
Background: Leprosy is one of the infectious diseases of public health importance; it is the leading cause of permanent physical disability as aresult of nerve damage. Individuals with leprosy have emotional stress and anxiety, which may lead to both psychological and psychiatric co-morbidity. Objective: This study was conducted to estimate the prevalence of mental distress among leprosy patients attending ALERT Specialized, Addis Ababa, Ethiopia. Method: Institution based cross-sectional study was conducted from April 2011-June 2011. Alternate patients from the daily register of outpatients were interviewed for symptoms of mental distress using the Self Reporting Questionnaire (SRQ-20). This questionnaire was administered by two trained nurses. Data was analyzed using SPSS version 15. Odds ratio were calculated to see the association of dependent variable with each independent variable. P-value <0.05 were considered as statistically significant. Result: The prevalence of mental distress was found to be 30.9%.Physical disability was also associated with mental distress. This study showed that mental distress was significantly higher in patients with leprosy. Conclusion: This piece of study...
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