Posted by admin on Apr 1, 2013 in |
Urinary tract infection is the most common disease in females and males which is big threat of kidney failure. The increasing interest is in the powerful biological activity of medicinal plant containing bioactive compounds which paves way for the importance to determine their antibacterial activity. The bioactive chemical determination revealed the presence of bioactive constituents’ steroids, alkaloids, tannins and flavonoids due the color change in the reaction tubes. While the absence of terpenoids saponins and glycosides as there was no color change in the reaction tubes. The total flavonoid content was 16mg/gram while total phenolic compound was 0.9grams in the leave extract of Camellia sinensis. The reducing power was found 0.13grams/gram of leave extracts. The phenolic extract of Camellia sinensis showed the antibacterial activity against Pseudomonas fluorescens and Serratia Spby showing maximum zone of inhibition around the bacterial colonies when compared with standard antibiotics Cotrimaxazole, Norfloxacin, Chloramphenicol, and Nalidixic...
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Posted by admin on Apr 1, 2013 in |
The antimicrobial and antioxidant activity of four different solvent extracts of P. florida were investigated. The antimicrobial activities of different solvents were tested against different bacteria and fungi using disc diffusion method. Total antioxidant, reducing power and total phenolic content effect of the extracts was determined by phosphomolybdenum assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and Folin-Ciocalteu method. Results indicated that the maximum antibacterial and antifungal activity was observed in ethanol extract of P. florida was found at 23 mm and 20mm against Streptococcus sp and E. floccosum respectively. Ethanolic extract of P. florida produced minimum inhibitory concentration (MIC) at 25mg/ml against E. coli followed by K. oxytoca (25mg/ ml), P. murabilis (75mg/ml) and Streptococcus sp. (50mg/ml). The ethanol extract exhibited good antioxidant activity (230 µg equivalent of BHT/g), strongest reducing power inhibition (79.24%) and also contain high phenolic content (6.25 mg gallic acid/g of dry extract). The results provided evidence that the ethanolic extracts of P. florida might indeed be potential sources of natural antioxidant and antimicrobial...
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Posted by admin on Apr 1, 2013 in |
Cow urine therapy and all traditional practices from Indian systems of medicine have a strong scientific base. The cow has proved to be a boon in the areas of agriculture, science and technology, industry, energy, medicine etc for the development of any nation, in addition being eco-friendly in nature. In the present study the antibacterial potentials of cow urine were investigated. Total 14 pathogenic and non-pathogenic bacterial cultures were used as test organism against 10 different cow urine samples. The highest zone of inhibition was shown by sample G against P aeruginosa NCIM 2945 (1.8cm) while the smallest zone of inhibition was shown against E. coli NCIM 2065(0.3 cm) by sample A. Based on cumulative effect against the test organism, the urine sample G was found to be the most efficient inhibiting all the 14 test cultures. The antibacterial activity reported by sample G was comparable with standard antibiotics. A higher zone of inhibition was observed by sample G against P aeruginosa NCIM 2945 as compared to that of...
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Posted by admin on Apr 1, 2013 in |
Impacts of sodium and potassium in diet to determine offspring gender in hamsters have been investigated. Sex determination has scientific basis for prevention of genetic diseases in addition to social backgrounds.20 healthy hamsters chosen from the first generation of the previous experimental hamsters, were divided in to two groups in the hamsters male to female 1:5. The first group was Na and K, the second group was control unit without Na and K. It was found that the delivered offsprings male to female ratio were 2.06:1and 1:1, for the first and second groups respectively. Also, it was found that hamsters fed with (Na, K) food yields, numbers of offspring (135), while hamsters fed with normal food yields, numbers of male offspring...
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Posted by admin on Apr 1, 2013 in |
We have synthesized some new pyridazine-3-one derivatives and characterized by means of IR, NMR & mass spectral data. Compounds were evaluated for in-vitro antibacterial activity by disc diffusion method and further subjected to molecular properties prediction and drug-likeness by Molinspiration software. All compounds were found in compliance with Lipinski ‘Rule of Five’ and presented a good drug-likeness score with no violations. Compound I and IV having substitutent (6-phenyl, 6-chloro phenyl) has documented good antibacterial activity against S. aureus & S. epidermidis. Compound III & V (4’-chloro-benzylidine, 4’-methoxy-benzylidine)has reported good activity against P. aeruginosa & E....
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