Posted by admin on Sep 1, 2012 in |
Tinospora cordifolia is known for a wide range of medicinal properties. In this study, cardiovascular and antimicrobial properties of aqueous and ethanolic extracts of Tinospora cordifolia were evaluated. Dose dependent negative ionotropic and chronotropic effects were observed with both aqueous and ethanolic extracts. The effects were antagonized by atropine indicating involvement of muscarinic receptors. Maximum antimicrobial activity was found with ethanolic extract of Tinospora cordifolia (15mm) against Pseudomonas aeruginosa. The organism showed resistance to aqueous extract giving an inhibition zone of 0.3mm. The data suggest that Tinospora cordifolia could be of benefit in arrhythmias and microbial infections....
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Posted by admin on Sep 1, 2012 in |
Tridax procumbens L. is a well known medicinal plant. In the present study alkaloids from pedicle and buds of the plant were extracted and evaluated for antimicrobial activity by ‘Disc Diffusion Assay’ against selected bacteria (Escherichia coli, Staphylococcus aureus and Proteus mirabilis) and fungi (Aspergillus flavus, Aspergillus niger, Candida albicans and Trichophyton mentagrophytes). Minimum inhibitory concentration, minimum bactericidal/fungicidal concentration and total activity of each active extract were also evaluated. Significant antibacterial activity was recorded by alkaloids of pedicle against P. mirabilis (IZ 20mm, AI 0.83 and same MIC, MBC 0.039 mg/ml) and antifungal activity was recorded by buds against C. albicans (IZ 9.2mm, AI 0.92, MIC 0.625 mg/ml and MFC 1.25 mg/ml). MIC ranged from 0.039 mg/ml-0.625 mg/ml and MBC/MFC ranged from 0.039 mg/ml-1.25 mg/ml against susceptible pathogens. It is noteworthy that MIC values of active extracts was found very low (0.039 mg/ml-0.625 mg/ml) and was recorded below 1 mg/ml against inhibited pathogens, thus ascertain their strong antimicrobial potential against selected microbes. Thus, the result of the present study...
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Posted by admin on Sep 1, 2012 in |
Cassia nodosa Bunch.is an ornamental tree belonging to family Leguminosae, popularly known as Pink Shower is a perennial tree. Laboratory evaluations were made to asses the study of primary metabolites in different plant parts of Cassia nodosa Bunch. The highest amount of soluble sugars (10.27mg/ gdw), lipids (32.36mg/gdw), phenols (20.0mg/gdw), DNA (11.78mg/gdw) and Chlorophyll- a+b (0.94mg/gdw) was observed in pods, ascorbic acid (0.867 mg/gdw), proteins (115.0mg/gdw), RNA (4.60mg/gdw) and carotenoids (0.554mg/gdw) in leaves and starch (10.02mg/gdw) in stems. Similarly lowest amount of proteins (39.48mg/gdw), phenols (4.67mg /gdw), RNA (0.49mg/ gdw) and DNA (1.76mg/gdw) was observed in leaves, starch (3.76mg/gdw) in flowers, soluble sugars (2.45mg/gdw), lipids (3.48mg /gdw), ascorbic acid (0.089mg/gdw) in...
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Posted by admin on Sep 1, 2012 in |
The fruits of Garcinia pedunculata Roxb. ex Buch.-Ham., G. xanthochymus Hook. f. and G. morella (Gaertn.) Desr. collected from Sonitpur district of Assam, India were evaluated for the antioxidant potential and total phenolic content. The methanolic extract of these fruits were subjected to DPPH (2,2-Diphenyl-1-picrylhydrazyl) assay for determining the free radical inhibition property and Folin Ciocalteu’s method for quantification of total phenolic content (TPC). G. pedunculata Roxb. ex Buch.-Ham. showed highest antioxidant potential with IC50 value 47.03±13.48 µg/ml. All species contains low phenolic content ranging between 1.83±0.62 to 88.2±2.19 mg GAE/g dry extract. No significant correlation between total phenolic content and antioxidant potential was...
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Posted by admin on Sep 1, 2012 in |
Pollution have a serious impact on human health and environment. The incidences of various diseases are becoming prominent with the increase in rate of population. The diseases mainly include respiratory disorders, cardiovascular disorders, throat inflammation, skin infections etc. In the present study, widely claimed crude drug Dashamularishta, have been screened for their antibacterial activity against Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum. Phytochemical screening and antimicrobial activity of petroleum ether, chloroform, benzene, ethyl acetate and ethanol and distilled water extracts of Dashamularishta have been screened. Phytochemical screening recorded positive results for reducing sugar in all six extracts, terpinoids present in pet. ether, ethyl acetate, methanol and distilled water extract, Flavonoids present in ethyl acetate and distilled water, Tannin present in chloroform and methanol, saponins present in pet. ether, benzene, ethyl acetate and distilled water extract. The results were expressed in terms of the diameter of the inhibition zone: The maximum efficacy of ethyl acetate extract was...
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