Posted by admin on Nov 1, 2011 in |
The present study was to evaluate the in vitro cholesterol esterase enzyme inhibitory and in vitro antioxidant activity of the methanol extract of the leaves of Camellia sinensis (L.). Phytochemical screening of the extract shows the presence of flavonoids, phenolics and terpenoids. The extract shows ability to inhibit the enzyme with IC50 (82.46±0.74µg/ml) where as that of standard, Orlistat (24.15±0.59µg/ml). Antioxidant and free radical scavenging activity were also assessed by using the methods, IC50 values for Nitric oxide radical scavenging activity (396.83±0.83µg/ml), whereas for standard curcumin (260.38±0.66µg/ml), hydroxyl radical scavenging activity (47.04±2.26µg/ml) and for quercetin (70.99±1.31µg/ml). Moreover, the extract was found to scavenge the superoxide with 50% inhibition at 308.17±23.25µg/ml and standard ascorbic acid at 225.08±2.44µg/ml, IC50 for ferrous chelating ability assay (44.12±4.63µg/ml) and of ascorbic acid (47.25±.89µg/ml). Total content of flavonoids present in 1mg of extract was 19.8±0.11 µg quercetin equivalents/mg. Results indicated that the extract shows potential bioactive compounds which might have a beneficial impact on diseases related to cholesterol synthesis and showed potential antioxidant and free...
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Posted by admin on Nov 1, 2011 in |
Adhatoda zeylanica Medicus is a well-known plant drug in Ayurvedic, Unani-Tibbi, Siddha, Allopathic, Homeopathic, Naturopathic & Home Remedies. The present communication deals with the pharmacognostic evaluation on the stem and root of Adhatoda zeylanica Medicus (Acanthaceae). Macroscopic and microscopic examinations of the different organ, observations, and differential microchemical test has been carried out for the authentication of the samples. Physiochemical values such as the percentage of total ash, acid insoluble ash, acid soluble ash, extractive values like petroleum ether-soluble extractives, alcohol-soluble extractives and water-soluble extractives were calculated as well as histochemical tests and colour reactions with different chemicals were performed....
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Posted by admin on Nov 1, 2011 in |
The potential antioxidant effect ethanol induced liver damage was investigated using crude methanolic extract of the whole plant of Mollugo pentaphylla Linn. The standard drug used was ascorbic acid mg / kg/day. Serum cholesterol, triglycerides aspartate amino transferase (AST) and alanine amino transferase (ALT) levels were measured as antioxidant indicators. There was a significant reduction in the elevated serum enzymes, triglycerides and total cholesterol levels. The histopathologial studies revealed that the liver cells undergoing hydrobic and fatty changes indicating hepato cellular damage in the case of ethanol administration while extract treated animals showed mostly normal hepatocytes and mild hydrobic changes. Hence the study concluded that the plant exhibits antioxidant property....
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Posted by admin on Nov 1, 2011 in |
This study was designed to present the observation of the pharmacological properties to the bulb of the plant. The extract of the bulb of Urginea indica Kunth were collected by using of alcoholic extraction. The anti-inflammatory action of the alcoholic Extract of the bulb of the plant Urginea indica was evaluated in rats (female) against carrageenan induced edema i.e., using plethysmographic method. Besides this method, this extract was also assessed for Cotton pellet test and Hot plate test for anti-inflammatory and analgesic effects respectively. The effects of the extract were compared with the classical anti-inflammatory drug – Ibuprofen. The crude extract and the standard drug were orally administered. A significant anti-inflammatory effect was produced with the Alcoholic Extract of the plant part. This effect was then compared with the effect from the classical anti-inflammatory...
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Posted by admin on Nov 1, 2011 in |
Analysis of fatty acid composition in fixed oil extracted from Sterculia foetida Linn. (Sterculiaceae) seed was done with the help of GC-MS. The structural identification was done by preparing FAME of the fixed oil and then subjected to GC-MS wherein Flame Ionization Detector was used. The oil constituted of 7 fatty acids whose carbon chain length, degree and position of unsaturation were determined from the characteristic ionization and fragmentation of FAME resulting from GC-MS electron impact, chemical ionization modes. The fatty acids found in the oil were methyl esters of tetradecanoic acid (Myristic acid) (1.65%), hexadecanoic acid (Palmitic acid) (11.87%), 9-Octadecenoic acid (Oleic acid) (20.50%), 7, 10-Octadecadienoic acid (Linoleic acid) (20.50%), 8-(2-Octacyclopropen-1-yl)octanoic acid (Sterculic acid)...
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