Posted by admin on Nov 1, 2011 in |
Many herbal remedies have been employed in various medicine systems for the treatment and management of the different diseases. The Tamarinds indica commonly known as ‘imali’ has been recognized in different system of traditional medicines for the treatment of different diseases and aliments of human being. This review supports of all updated information on its pharmacognostical, pharmacological activity and traditional uses. Preliminary phytochemical screening of this plant revealed the presences of, flavonoids, steroid, glycoside alkaloid and Triterpenoids. It has been reported as Anti-helminthic, antimicrobial, antiseptic, antiviral, asthma, astringent, bacterial skin infections, constipation (chronic or acute), and diabetes. There is no report available on isolated constituents of bioactive compound from plant bark of Tamarinds indica which supports it’s further to isolating a useful pharmacologically active compound as a...
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Posted by admin on Nov 1, 2011 in |
The present study was to investigate the anti-obesity effects of the freeze dried powder of ethanolic extract of Licorice (Glycyrrhiza Glabra) (LP) in a rat model of high-fat diet induced obesity and hyperlipidemia. Male wistar rats were fed with a high-fat diet for 8 weeks to induce obesity and hyperlipidemia. High fat diet induced obese rats exhibited increases in body weight gain, adipose tissue mass and levels of serum glucose, triglycerides and total cholesterol compared to rats fed a normal chow diet. However, administration of LP (100-400 mg/kg, o.d., p.o) along with high-fat diet for 8 weeks significantly reduced high fat diet-induced increases in body weight gain and adipose tissue mass in a dose dependant manner. Moreover, LP attenuated high fat diet induced increased levels of serum glucose, triglycerides and total cholesterol. The antiobesity effects of LP were comparable to orlistat, a well reported pancreatic lipase inhibitor. The antiobesity activity of LP appears to be mediated by decreasing dietary fat absorption from the intestine as LP dose dependently attenuated...
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Posted by admin on Nov 1, 2011 in |
Bacopa monnieri Linn. is an important medicinal plant belonging to family scrophulariaceae. Bacopa is a neurotonic, immuno-modulator, tranquilizing, memory and learning enhancing, cerebral activator, anti-ulcer, antispasmodic, anti-asthmatic. It is also used in Epilepsy, anxiety and depression. Major component of Bacopa are saponins Bacoside A and Bacoside B. The cell suspension culture of Bacopa monnieri was treated with 0.2%, 0.6% and 1% concentrations of DMSO (Dimethyl sulphoxide), a cell permeabilizing agent for 3 and 6 hours. The samples were analyzed for the content of bacoside A using HPTLC technique to identify and quantify the amount of released product. Maximum release of bioactive compound, Bacoside A was observed (4.6±0.02µg/mg) in suspension culture treated with 1% DMSO for 3 and 6 hrs treatment durations compared to control (2.1±0.05 and 3.2±0.01,...
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Posted by admin on Nov 1, 2011 in |
Purpose: Primary fallopian tube carcinoma (PFTC) is a rare tumor that histologically and clinically resembles to epithelial ovarian cancer (EOC). The purpose of this study is to present a case history, treatment & review the current available literature on PFTC. Material, methods and results: Early clinical presentation and prompt investigation often lead to diagnosis at an early stage. The diagnosis of PFTC is rarely done preoperatively and is usually detected by the pathologist. Surgical staging, management and the use of combination chemotherapy based on concepts similar of epithelial ovarian cancer (EOC).The timely diagnosis of PFTC leads to better survival compared with EOC. However, as with EOC, stage and residual tumors are the most important prognostic variables. Conclusion: Tumors of the fallopian tube can be suspected pre-operatively with current radiological facilities. Aggressive clinical search should also be made for a concomitant primary or as an isolated metastatic secondary of another primary cancer. Until more extensive clinical research has been performed, ovarian carcinoma management principles should be used in clinical...
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Posted by admin on Nov 1, 2011 in |
Fluoxetine hydrochloride (FH) in combination with Olanzapine (OZ) is used in treatment of depressive episodes associated with bipolar disorder. The first derivative spectrophotometric method for simultaneous determination of fluoxetine hydrochloride (FH) and olanzapine (OZ) from two component tablet dosage form has been developed and validated. Chromatographic methods viz. HPLC and HPTLC methods were reported in the literature for the simultaneous determination of FH and OZ from combined dosage forms. In the present investigation an attempt has been made to develop accurate, reproducible, rapid and cost-effective method for simultaneous determination of FH and OZ in pharmaceutical formulation. The wavelengths selected for determination of FH and OZ is 235.5nm and 296nm, respectively. The beer’s law was obeyed in the concentration range of 8-80μg/mL and 2-20μg/mL for Fluoxetine and Olanzapine, respectively. The proposed methods were validated and successfully applied to the determination of FH and OZ in tablet formulations. The results suggested that the proposed procedures can be used for routine quality control of tablets containing FH and...
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