Posted by admin on Sep 1, 2011 in |
A reverse phase HPLC method is described for the determination of Ziprasidone HCl capsule by analytical method. Chromatography was carried out on an ODS C18 column using a mixture of buffer solution, acetonitrile and methanol (45: 40: 15v/v/v) as the mobile phase at a flow rate of 1.5mL/min. Detection was carried out at 230nm. The retention time of the drug was 7-9 min. The method produced linear responses in the concentration range of 50-150µg/mL of Ziprasidone .The method was found to be applicable for determination of the drug in...
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Posted by admin on Aug 1, 2011 in |
Objectives: The present study was carried out to evaluate the anti-inflammatory effect of extracts of leaves of Vitex trifolia Linn. (Verbaneaceae). Methods: The anti inflammatory activity of plant extracts at different dose intervals was evaluated by using two models Carrageenan induced rat paw edema and Xylene induced ear edema in Mice. Acute inflammation in rats was induced by injecting Carrageenan (0.1 ml of 1% suspension in 0.9% saline) in subplantar region and topical application of xylene (0.03ml)to the anterior and posterior surface of mice ear. The mean paw volume and percent reduction in ear edema were evaluated. Results: Significant reduction in Paw volume (P<0.01) and ear edema were observed in all treated groups. Alcoholic extract showed more activity than aqueous extract and also in dose dependent manner. Conclusion: The study showed that the leaves of Vitex trifolia Linn. (Verbaneaceae) possess an anti-inflammatory...
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Posted by admin on Aug 1, 2011 in |
Incidence of cancer in northeast is the highest in India. Nutrition intervention plays a vital role in the management of postponement of cancer. Objectives: To find out the prevalence rate of different types of cancer among the selected male tribal population of Shillong and dietary habits of these tribes the present study was carried out. Methods: Three hospitals from the city of Shillong was followed up for a period of three months, a total of 125 male inpatients and outpatients visiting during the period were interviewed with well-structured interview to collect data on background information, disease history, anthropometric measurement, clinical assessment, biochemical assessment, lifestyle or health hazards, dietary hazards and dietary assessment including weighment survey to assess for the nutrient intake of the cancer patients for three consecutive days. The PGSGA scoring was done to find the suitable level of intervention strategies. Nutrition intervention through Macrobiotic Approach was given to the patients and their family members using pamphlets, booklet and an e-content. Results: It was found out during the...
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Posted by admin on Aug 1, 2011 in |
Bindens pilosa L. is a cosmopolitan weed, originally from South America and common in all tropical and subtropical areas of the world. It is a small annual weed occurring all over the country. Roots, leaves and seeds have been reported to possess antibacterial, antidysentric, anti-inflammatory, antimicrobial, and hypotensive activities. Extracts of this plant is used in southern Africa to cure malaria. In tropics also it is used on snakebite and malaria. It is used in traditional medicine as a remedy to treat glandular sclerosis, wounds, colds, flu and urinary tract infections. Leaf extracts in petroleum ether, chloroform, acetone, methanol and distilled water were tested against five bacteria. Maximum zone of inhibition was produced by acetone and petroleum ether extract against Proteus vulgaris, and least activity by methanol and aqueous extract against bacillus...
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Posted by admin on Aug 1, 2011 in |
Since ancient times, plants have got medicinal importance. Ethno medicinal use of plants is very common in rural parts of India. Various constituents of these plants have shown profound therapeutic and prophylactic activities. The present research work is conducted to investigate invitro antimicrobial activity of various extracts of seeds of plant Cleome viscosa Linn. The petroleum ether, chloroform, ethyl acetate, ethanol & water extract of seeds of plants were screened against eight microbial species. Clinical samples of pus from earache patients were also used. The test materials have shown significant antimicrobial activity. The zones of inhibition are found to be between 10 mm to 17 mm. The minimum inhibitory concentration (MIC) values of extracts are also determined against microorganism which ranges from 0.1 to...
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