Posted by admin on Mar 1, 2011 in |
The aim of the present investigation was to evaluate the antimicrobial efficacy of methanolic extract of whole plant of Nelumbo nucifera Gaertn. The methanolic extract of Nelumbo nucifera were tested for antibacterial efficacy against three gram positive bacteria & three gram negative bacteria and antifungal activity against three fungal strains by disc diffusion method. In present study Ciprofloxacin 100 mcg/ml (antibacterial) and Ketakonazole 100 mcg/ml (antifungal) used as a reference standard. The methanolic extract of Nelumbo nucifera at the concentration of 150mcg/ml were found significant antimicrobial activity against the entire organism was tested. This study scientifically supports the usage of whole plant as a remedy for various superficial bacterial and fungal infections in traditional...
Read More
Posted by admin on Mar 1, 2011 in |
This study was undertaken to investigate the antidiabetic activity effect of repeated oral administration of the methanolic extract of Caesalpinia digyna (Family: Leguminosae) in normal and streptozotocin induced diabetic rats, respectively. The effect of repeated oral administration of methanolic extract on serum lipid profile in diabetic rats was also examined. The doses, viz. 250 and 500mg/kg bw of methanolic extract of Caesalpinia digyna (CD) were evaluated and the dose of 500 mg /kg was found to be the most effective dose. The same dose of 500 mg/kg produce significant fall in blood glucose level after 1h during glucose tolerance test. The dose has almost similar effect as similar to that of glibenclamide (0.4 mg/kg bw). The diabetic rats treated daily with 500mg/kg bw for 15 days produced a significant reduction in the fasting blood glucose level and increase in body weight of diabetic rats was additional corroborating factors for its antidiabetic potential. Total cholesterol (TC), low density lipoprotein (LDL) and triglycerides (TG) levels were significantly (p<0.01) decreased when compared...
Read More
Posted by admin on Mar 1, 2011 in |
The aim of the present investigation was to evaluate the antimicrobial efficacy of methanolic extract of whole plant of Nelumbo nucifera Gaertn. The methanolic extract of Nelumbo nucifera were tested for antibacterial efficacy against three gram positive bacteria & three gram negative bacteria and antifungal activity against three fungal strains by disc diffusion method. In present study Ciprofloxacin 100 mcg/ml (antibacterial) and Ketakonazole 100 mcg/ml (antifungal) used as a reference standard. The methanolic extract of Nelumbo nucifera at the concentration of 150mcg/ml were found significant antimicrobial activity against the entire organism was tested. This study scientifically supports the usage of whole plant as a remedy for various superficial bacterial and fungal infections in traditional...
Read More
Posted by admin on Mar 1, 2011 in |
Mucoadhesive microcapsules of verapamil, a peripheral vasodilator, used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, have been prepared from sodium alginate, hydroxypropylmethyl cellulose- K4M & E5LV, Carbopol 934P using 10% w/v calcium chloride solution by ionic gelation method. Drug : polymer ratio was 1:1 in all formulations and polymer mixtures employed were 1:1, 2:1, 3:1, 4:1 of sodium alginate: polymer (hydroxypropyl methyl cellulose- K4M & E5LV, carbopol 934P). Calcium chloride was used for ionic gelatin and cross linking of sodium alginate molecules. Microcapsules were spherical in shape and of sizes between 580 microns to 831 microns. Carbopol 934P was found most effective in controlling drug release from microcapsules followed by hydroxypropyl methyl cellulose- K4M. Drug releases from the best formulations of carbopol 934P and hydroxypropyl methyl cellulose-K4M follow anomalous...
Read More
Posted by admin on Mar 1, 2011 in |
The aqueous, methanolic and saponin extracts of Zizyphus mauritiana barks has been screened for antimicrobial activities against some human vaginal pathogens Staphylococcus aureus, Pseudomonas aeruginosa, streptococcus facecalis, klebsiella pneumoniae, Escherichia coli, Enterobacter faecalis, Enterobacter faecium and Proteus mirabilis isolated from patient samples. Extracts were found to produce significant inhibition against all the pathogens. Saponin extract were observed to be more active than methanolic and aqueous fraction. Extracts are found to be more active against Staphylococcus aureus and Escherichia coli...
Read More
