Posted by admin on May 1, 2011 in |
To study the anti-inflammatory effect of different extract of leaves of Diplazium esculentum in rats. Anti-inflammatory activity was screened by measuring the reduction in carrageenan induced hind paw edema. The potency of various extracts of leaves was compared with each other and standard Ibuprofen (100mg/kg) for anti-inflammatory activity. The results indicated that all the extracts of Diplazium esculentum showed anti-inflammatory activity. Percentage inhibition of inflammation observed in chloroform extract group was more than other treated...
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Posted by admin on May 1, 2011 in |
Biodiesel is produced from vegetable oils (edible & non edibles) and animal fats. The methyl ester of vegetable oils, known as biodiesel are becoming increasingly popular because of their low environmental impact and potential as a green alternative fuel for diesel engine and they would not require significant modification of existing engine hardware. At present, biodiesel is commercially produced from the refined edible vegetable oils such as Schlichera oleosa seeds oil, etc. by alkaline-catalyzed esterification process. This process is not suitable for production of biodiesel from many unrefined non-edible vegetable oils because of their high free acid value. Hence, a two-step esterification method is developed to produce biodiesel from high FFA vegetable oils. The biodiesel production method consists of acid-catalyzed (H2SO4) pretreatment followed by an alkaline-catalyzed (KOH) transesterification. Methyl ester of Schlichera oliosa is derived through esterification and transesterification...
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Posted by admin on May 1, 2011 in |
Objective: To assess and educate about home medicine cabinet among randomly selected houses of people in community of Greater Noida city & to carry out the survey of medicines proper storage, safe use, list of total and expired drugs, their disposal and maintenance of home medicine cabinets. Method: This study was a simple randomised prospective survey study. This prospective study was carried out for a period of six months in selected areas of Greater Noida City. The study site was the homes sited in those areas by simple randomization. Key findings: Randomly selected 102 houses were visited to educate and assess the people about Home Medicine Cabinet. A total of 392 people were surveyed in 92 houses with exception of 10 houses. During the period of the study, most of the expired drugs are in the category of analgesics and NSAID’s (23.93%) followed by nutritional supplements (22.56%), antibiotics (14.94%), expectorants and mucolytics (6.77%), bronchodilators (5.31%) and antacids (6.53%),Number of House members involved in self medication decreased from 72 houses...
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Posted by admin on May 1, 2011 in |
The present study deals with the Pharmacognostical and preliminary phytochemical studies of fruit pulp of Aegle marmelos. Macroscopy, organoleptic characters, microscopic features, physiochemical standardization parameters such as total ash, acid insoluble ash, water soluble ash, alcohol, water and other organic solvent extractives, preliminary phytochemical assay, fluorescence analysis and microbial limit assay were performed using standard textual methods. The Pharmacognostical results showed the following observations that are total ash (3.8%), acid insoluble ash (2.05%), water soluble ash (2.9%), water extractives (12%), alcoholic extractives (10.4%), foaming index (333.3U), and swelling index (3.3%). Fruit pulp reveals the presence of steroids, terpenoids, flavonoids, Saponins, phenolic compounds, lignin, fat and oil, proteins, carbohydrates, amino acids and reducing sugars. These observations would be of immense value in the botanical identification and standardization of drugs in a crude...
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Posted by admin on May 1, 2011 in |
Salbutamol (SAL) and Ambroxol (AMB) is used for the treatment of asthma and bronchitis. Two simple, economical, accurate, and precise methods for simultaneous estimation of Salbutamol Sulphate (SAL) and Ambroxol Hydrochloride (AMB) in tablet dosage form have been developed. The methods are absorbance correction method (I) and first order derivative method (II). In first method ambroxol hydrochloride (AMB) was determined directly from calibration plot by measuring absorbance at 300nm and salbutamol sulphate (SAL) was determined after correction for absorbance of ambroxol hydrochloride (AMB) at 223 nm. Second method is based on first order derivative spectroscopy to overcome the spectral interference from the other drug. Wavelength 252 nm was selected for SAL and 232 nm for AMB. Both the methods showed linearity in the concentration range of 2-10µg/ml for SAL and 2-20 µg/ml for AMB. The accuracy and precision of the methods were determined and the methods validated stastically. No significant difference was observed between the results obtained by the two...
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