Posted by admin on Oct 1, 2010 in |
Infectious diseases are the second leading cause of death worldwide. Treatment of infections continues to be problematic in modern time because of the severe side effects of some drugs and the growing resistance to antimicrobial agents. Butea monosperma (L) bark ethanolic and aqueous extract has shown good efficacy against Bacillus cereus. Pseudomonas aerugenosa and Escherichia Coli in concentration dependent manner which were grown on MH- Agar medium. 1000mg/ml has shown better zone of inhibition (ZOI) in all the cases of above micro...
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Posted by admin on Oct 1, 2010 in |
Guava is one of the most liked fruit items in Ethiopia and has its own economical importance. In concern with that a project experiment cum survey was carried out on the prevalence of post-harvest diseases of guava was conducted in Aksum in the months of January and March, 2009. During the experiment, 80 samples of diseased guava fruits were collected from different sites of Aksum, Ethiopia. The isolation of post harvest pathogen and analysis of diseased guava fruits was carried out and found that the prevalence of maximum fungi found to be Pestalotia psidii about 32.16% was the major post harvest pathogen isolated from the samples, followed by Rhizopus stolonifer (16%), Aspergillus niger (10.40%), Penicillium expansum (7.20%), Rhizoctonia solani (3.20%) and Fusarium sp. (1.6%). This study is an initiation for the effective post harvest management practice to increase the shelf life of guava and minimize the loss of post harvested guava in the coming...
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Posted by admin on Oct 1, 2010 in |
This study evaluated the in vitro antioxidant and cytotoxic potential of methanolic extract of the rhizome of Costus speciosus (Zingiberaceae). The different antioxidants assays including total antioxidant activity, DPPH, nitric oxide (NO) scavenging, total phenolic content and flavonoid content were studied. Costus speciosus exhibited potent total antioxidant activity which was expressed as an equivalent of ascorbic acid mg/g plant extract. In addition, Costus speciosus had effective free radical scavenging, nitric oxide scavenging activity, total phenolic content and flavonoid content depending on concentration. These various antioxidant activities were compared with the standard antioxidants ascorbic acid and quercetin. The extract of the rhizome of Costus speciosus also demonstrated a strong cytotoxic activity against brine shrimp nauplii with an LC50 value of 31.55...
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Posted by admin on Oct 1, 2010 in |
The dried aerial parts of Cardiospermum halicacabum Linn were subjected to extraction using the solvents (petroleum ether, chloroform, Ethyl acetate and ethanol) in increasing order of polarity. The prepared extracts were then subjected to preliminary phytochemical analysis. It was found plant possesses carbohydrates, alkaloids, sterols, flavanoids and saponins. All extracts were selected for further study. The analgesic activity of all extracts of aerial parts was assessed in albino mice using thermal stimulus model. morphine and Paracetamol were used as standard. The results indicate that, petroleum ether extract showed 34% (0.15mg/ml) and 58 %( 0.3mg/ml) significant activity, when compared with morphine. Comparison with Paracetamol the pet ether extract showed 48% (0.3mg/ml) and 82% (0.3mg/ml) significant activity. The ulcer activity was determined by pylorus ligation technique. Ranitidine (50mg/kg) used as standard. The ethanol extract showed 48.2% (18.75mg/2ml) significant antiulcer activity compared with standard drug. From the present study it may be concluded that the constituents present in all the extracts may be responsible for both...
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Posted by admin on Oct 1, 2010 in |
The present study was undertaken to evaluate antioxidant and hypolipidemic activity of Vedic guard, a polyherbal formulation comprising of Terminalia arjuna, Withania sominefera, Bacopa monnierii, Tinosporia cardifolia, Commiphora mukul and many other plant extracts, all of which are classifieds in Ayurveda as Rasaayanas which are reported to promote antioxidant and hypolipidemic activity. Antioxidant activity has been established in young adult rats against antitubercular drug induced hepatotoxicity but not in geriatric rats. Antioxidant activity was evaluated by hepatoprotectivity against carbon tetrachloride induced liver toxicity for 21 days in geriatric rats using Silymarin as reference standard, and by pyrogallol induced immunosupression for 28 days in young adult rats using levamisole as reference standard. Hypolipidemic activity was evaluated using triton WR1339 induced hyperlipidemic rats as experimental model in acute study. Oxidative damage was evidenced by occurrence of liver cirrhosis, elevation of AST, ALT, and ALP, total bilirubin in blood serum and increased LPO, reduced CAT and GSH in liver homogenate. Vedic guard treatment in geriatric rats with doses of 90mg/kg, 180mg/kg b....
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