Posted by admin on Feb 1, 2010 in |
The antimicrobial activities of aqueous, ethanolic and petroleum ether extracts of the leaves of Basella rubra were evaluated in the present study by measuring the inhibition zones using Cup Plate Diffusion method. The inhibition zones were significantly different (P<0.001) in each plant extract. The ethanolic extract showed maximum activity with zone of inhibition (14.3±1.82 mm) against E.coli, followed by aqueous extract (13.4±1.2 mm) and petroleum ether (5.6±0.62 mm) at a concentration of 50g/ml. Ciprofloxacin was used as the standard drug having zones of inhibition(17±0.34 mm) against E.coli and 19±0.18 mm against A. niger. Microbial inhibition was in the order E.coli (12.57±0.99), A. niger (11.68±0.71), V. cholera (11.42±0.60), S. aureus (10.71±0.46), S. typhi (9.80±0.90) , respectively with all the extracts. The extracts were not able to inhibit the growth of P....
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Posted by admin on Feb 1, 2010 in |
Vasicine is a pyrralazoquinazoline monobasic alkaloid obtained from the Plant Adhatoda vasica. In the present paper, the experiment were carried out to synthesis the various analogs of Vasicine, where the five membered ring C, was converted to seven membered ring, thus producing 7,8,9,10-Tetrahydroazepino[2,1-b] quinazolin-12(6H)one (RLX), was reported to be 6-10 times more potent than aminophylline as a bronchodilatory agent. A series of new compounds were synthesized, as modification in ring A and in ring B. The resulted compounds were evaluated for the antihistaminic activity to synthesis even more potent compounds....
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Posted by admin on Feb 1, 2010 in |
Thespesia populnea is a reputed ever green tree belonging to the family malvaceae; commonly known as Indian tulip tree. The plant is distributed tropical regions and coastal forest in India. It is well known and all the parts are used in traditional system of medicine. The plant has been used as astringent, antibacterial, hepatoprotective, haemostatic, anti-diarroheal and anti-inflammatory. The shade dried bark powder of Thespesia populnea was subjected to successive extraction using the solvents (Pet. ether, chloroform, alcohol and water). The diuretic potential of various extract of the barks was assessed in albino rats. The Volume of urine, urinary concentration of Na+, K+ and Cl– ions were the parameters of the study. Fursemide (100 mg/kg) was used as standard. The extract (400 mg/kg) has shown significant increase in the volume of urine, urinary concentration of Na+, K+ and Cl–. From the present study it may be concluded that the extract possess polyphenolic compounds, carbohydrates, proteins and possess natriuretic and diuretic...
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Posted by admin on Feb 1, 2010 in |
Nyctanthes arbortristis Linn. (Oleaceae) which has been used as an antiepileptic remedy in tribal people of India (Orissa and Bihar) along with its use in Ayurveda, Sidha and Unani systems of medicine was evaluated for anticonvulsant activity against experimental seizures. The leaves ethanolic and aqueous extracts of N. arbortristis protected mice against tonic convulsions induced by maximal electroshock and especially by pentylenetetrazole. Neurotoxicity (sedation and motor impairment) of the extract was assessed by the rota rod test. Preliminary phytochemical analysis showed the presence of alkaloids, tannic acid, flavonoids, iridoid glucosides and Desramnosylverbascoside in the extracts. The acceptable acute toxicity of the extracts recommends further studies to determine the mechanism(s) and compound(s) involved in the anticonvulsant...
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Posted by admin on Feb 1, 2010 in |
Root Extracts of Beta vulgaris; Smilax regelii; & Cucurbita maxima. seed is effective for reducing fats individually as well as its combination effort through different mechanism. First one is used to flush out fats from the system and the second & third is used to regulate thyroxine. The extract of A,B & C were taken with diffusion extraction, ethanol extraction through soxhlet apparatus and through Kjeldahl extraction method. Toxicity LD50 study was taken into 15 mices in three divided categories – B, C and A&B&C gives 2.82+0.35, 4.48+0.130 & 2.82+0.277 respectively. Affectivity was evaluated to the extracts of Beet, Sarsaparilla, Pumpkin seed and its combination which gives 500 mg, 250 mg, 150 and 500 mg /kg/day, after administered orally, effectiveness to reduce fats were done in 5 guinea pigs giving results of mean weights 909.6 + 2.07 (control), 905.8 + 2.16 (extract-A), 906.42 + 2.24 (extract-B), 905.42 + 2.05 (extract-C), 905.42 + 2.05 (extract-B&C), 904 +1.499 (B&A), 902.53 + 1.7 (A&B&C). The t-test and the P value of C;...
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