Posted by admin on May 31, 2022 in |
Determine the fungicidal activity of five disinfectants on Candida auris of clinical and environmental origin. Assess the fungicidal efficiency of each disinfectant on the microorganism. Calculate the percentage of efficiency (% E) of each disinfectants on Candida strain and determine the specific death rate (k) and decimal reduction time for microorganisms. Analytic and experimental research with quantitative methods. We realized a strain’s workbench by culturing it in corresponding culture media. Analysis was a challenge essay, performed on four surfaces and at different exposure times; 1, 5, 15, and 30 minutes of contact between disinfectant and yeast. Once the disinfection process was carried out, what was expected was that after 15 minutes of contact between the yeasts and the disinfectants, a percentage of inhibition of the microorganism between 90 and 95% was presented, thus guaranteeing the duration of elimination of the infectious agent by disinfectants. Results show that after one minute of contact between Candida auris and disinfectant in a gloved hand, the yeast was removed when the clinical and...
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Posted by admin on May 31, 2022 in |
Background & objectives: Diallyl disulphide (DADS) is an active component of garlic that has been claimed to have hypoglycemic effect and are beneficial in achieving glycemic control in diabetes mellitus (DM). The present study was conducted to assess the glucose utilization in erythrocytes in diabetic subjects after the exposure of DADS. Methods: The blood samples were collected from diabetic subjects; the plasma and erythrocytes were separated. The fasting plasma glucose levels were measured and the separated erythrocytes from diabetic blood samples were preincubated and posted incubated with DADS. The glucose utilized by erythrocytes and the percentage of glucose utilization were measured. Results: The present study results showed that diabetic erythrocytes exposed to DADS showed a significant rise of glucose utilization compared to untreated erythrocytes, which signifies the positive influence of DADS on glucose utilization in diabetic patients’ erythrocytes. Conclusion: DADS, through the formation of thiol derivatives, promotes glucose utilization by mimicking the actions of insulin in diabetic erythrocytes after post-incubation. This study can be concluded that DADS can be...
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Posted by admin on May 31, 2022 in |
Alcoholic peripheral neuropathy is a potentially incapacitating complication of long-term excessive consumption of alcohol characterized by pain and dysesthesias, primarily in the lower extremities. The neurological effects of ethanol consumption are complex, encompassing both the central and peripheral nervous systems. It breaks into acetaldehyde which impairs and destroys the majority of neuronal functions. As a result, signals become intensified from the injured neurons and the nearby surrounding neurons, resulting in a painful condition. The study aims to evaluate the different doses of Erythropoietin, i.e., 250U/kg and 500U/kg, in alcohol-induced peripheral neuropathy. The present study involved evaluating the neuroprotective activity of Epo in alcohol-induced PN in rats by assessing behavioral, biochemical and electrophysiological, liver function tests, parameters. This study concludes that the two doses of Epo improved sciatic nerve conduction, behavioral studies and antioxidant activity in sciatic nerve homogenate. Among the two different doses of Epo, 500U/kg was most effective besides showing neuroprotective properties against alcohol-induced...
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Posted by admin on May 31, 2022 in |
The medicinal plant Jasminum flexile is reported in traditional medicine as an antidiabetic and anti-inflammatory agent. There is no scientific report on the antibacterial and anti-inflammatory activity of extracts of Jasminum flexile. This study investigated the antibacterial and anti-inflammatory potential of the hydroethanol extract of leaves of Jasminum flexile, its column fractions and constituent compounds. The column fractions MF14, MF9 and MF5 expressed a zone of inhibition of 12 mm against Streptococcus mutans and the isolated compound JFLC1 showed a zone of inhibition of 10 mm against Streptococcus mutans, Escherichia coli, and Klebsiella pneumoniae comparable to that of the standards ampicillin, kanamycin and chloramphenicol respectively at the same concentration. The highest anti- inflammatory potential was found for the column fraction MF3 (55.14%) as assessed from the percentage of haemolysis. The results reveal that the isolated compounds and extracts of leaves of Jasminum flexile possess significant antimicrobial and anti-inflammatory...
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Posted by admin on May 31, 2022 in |
Aim of study: A Randomized controlled trial was planned to evaluate the Clinical efficacy of Nidigdhikadileha an Ayurveda multi-dimensional herb preparation in children suffering from Recurrent Respiratory tract infection in children. Nidigdhikadileha contains Nidigdhika (Solanum Xanthocarpum), Pippali (Piper longum), Amrita (Tinospora cardifolia), and Nagar (Zingiber officinale). All these drugs have been described to have anti-tussive and antimicrobial properties. Material & methods: A total of 90 children, including male and female children, were studied for complaining of Recurrent Upper Respiratory Tract infections and were registered and divided into 3 groups (Group A, B, C). In group A, children were administered Nidigdhikadileha, dose180-200 mg/kg/dose twice a day for 2 months in children suffering from RURTI. In group B, honey drops were administered to 30 children at a dose of 1ml/kg/day, and in Group C there is also 30 patients were administered Sitopaladi churna at a dose 100 mg/kg/day. All the treated cases were assessed at each follow-up on the 14th day, 28th day, 42nd day, and 56th day, and post-follow-up was...
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