Posted by admin on Jun 30, 2021 in |
Linalool is the first ingredient to synthesize many other substances of higher value for the pharmaceutical and fragrance industry; therefore, finding sources of essential oils containing Linalool is an important and necessary task. The purpose of this study is to investigate Linalool of plants containing essential oil in Vietnam to extract Linalool sources for the pharmaceutical and fragrance industry. By the method of fresh sampling of essential oil plants in Vietnam, essential oils are extracted by steam distillation and then analyze on high-resolution chromatography (HRGC) to search for Linalool sources. We have found that some areas with a lot of plants containing high Linalool content grow concentrated wild in forests as Coriandrum sativum Linn., Homalomena occulta (Lour.) Schoot, Cinnamomum parthenoxylon Meissn, and some of them can be planned to cultivate the essential oil source to obtain Linalool for the pharmaceutical and aromatic industry. During the survey, we discovered and made a list of 21 plants with essential oil containing Linalool in...
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Posted by admin on Jun 30, 2021 in |
The present study aimed to explore the primary metabolites present in leaf, fruit, and seed crude extracts of Syzygium cumini L by Gas chromatography – Mass spectrometry. The compounds in the leaf, seed, and fruit extracts resulted from the GC-MS analysis was relevant to the National Institute of Standards and Technology (NIST) library. The metabolite profiling of the extracts revealed the presence of carboxylic acid and fatty acid found to be common in leaf, fruit, and seed extracts. And metabolites 6-oxa-3-thiaoctanoic acid, bisoprolol, phenacetin, tropin, alizarin, gonodoic acid are present in seeds that are not found in leaves and fruit metabolite profile. In contrast, Tetra decanoic acid, Azelaic acid, Penicillamine and S (-)-Cathinone are found only in leaves. Leaf, fruit and seed extracts of Syzyzium cumini L contains various bioactive compounds and consequently has a variety of medicinal properties for the treatment of different diseases like thyroid cancer, heart diseases, kidney stones and rheumatoid arthritis. Some metabolites found to be active as antidiabetic, anti-inflammatory, anti-cancerous, antioxidant, anti-bacterial and antifungal...
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Posted by admin on Jun 30, 2021 in |
Azadirachta Indica has always been known to be the bestowed with good health for many centuries in India. It has been found that the Neem is native to Asian countries. There are three major active components in A. indica, namely nimbin, nimbidin, and nimbiene. The compound nimbidin was isolated by chromatographic techniques. A. indica leaves extract was prepared, and the phytochemical analysis was conducted, and the phytochemical screening manifested the presence of alkaloids, flavonoids, reducing sugar, phenol, saponins and cardiac glycoside in the neem extract. Then qualitative phytochemical analysis was conducted for flavonoids, alkaloids, saponins, and phenol. Plant sources are considered the major active source of antioxidant molecules for a long time in the history of humankind. In the current study, the anti-bacterial properties of Neem have been tested against gram-positive bacteria, namely, Staphylococcus aureus, Bacillus subtilis, and gram-negative bacteria, namely, Escherichia coli Pseudomonas aeruginosa, Klebsiella pneumoniae, and proteus vulgaris. Chloramphenicol was used as a standard to analyze the effect of the nimbidin compound. The compounds obtained from plants...
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Posted by admin on Jun 30, 2021 in |
Succinimide and its derivatives are important substitutes of many medicinal compounds in the pharmaceutical field. One of the essential objectives in heterocyclic and medicinal chemistry is the synthesis of molecules having importance as therapeutic agents. Heterocyclic compounds and their derivatives contain an imide ring that can easily cross biological membranes in-vivo. Mannich reactions are one of the fundamental methods of C-C bond forming reactions in organic synthesis and withstand a diversity of functional groups. In view of this, the Mannich base1-((2,5-dioxopyrrolidin-1-yl)phenyl)methyl)thiourea and a few of its transition metal complexes with Mn(II) and Co(II) have been synthesized. The newly synthesized ligand and its metal complexes have been characterized by elemental analysis, molar conductance and FT-IR, UV-Visible NMR, Mass spectral studies, and magnetic measure-ments. The ligand and the corresponding metal complexes were screened for their antibacterial and antifungal activities. The metal complexes have shown marked activity against selected microorganisms than the...
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Posted by admin on Jun 30, 2021 in |
Background: Phytochemical profile and antioxidant studies are based on exploring plants for their use in the development of novel therapeutic drugs. Oroxylum indicum (OI), a valuable medicinal plant is native to India, found mainly in the Himalayan foothills and the Western Ghats. It has been used by traditional medicinal practitioners for a variety of ailments and is categorized as vulnerable medicinal plant by the government of India. Objectives: The present study was carried out to evaluate the phytochemical profile and antioxidant potential OI stem bark ethanol extracts. Methods: Phytochemical profiling and in-vitro antioxidant potential of stem bark were determined using standard protocols. The crude extract was subjected to LC-MS analysis for the identification of bioactive compounds. Results: The phytochemical analysis revealed the presence of compounds, namely glycosides, alkaloids, flavonoids, and tannins. At various concentrations tested, the increase in the free radical scavenging activity was observed with an increase in the concentration of extracts. The reducing power of the extract increased in a dose-dependent manner with an increase in concentration....
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